But he adds that, as with any drug that
suppresses autoimmunity, the risk that a diminished immune response could lead to infection remains a concern.
Not exact matches
Suppressing those signals could limit the
autoimmunity that causes inflammation in rheumatoid arthritis patients.
Experimental animal models have been used to investigate many aspects of the clinical disease such as the sex bias in myocarditis where testosterones in males promote
autoimmunity in the heart while estrogens in females
suppress virus infection and
autoimmunity.
On the other hand, boosting the ability of Tregs to
suppress other types of immune cells could prevent
autoimmunity, by preventing these cells from attacking organs and other tissues.
This proposed role for GM1 (and indirectly GD1a) provides a rationale for its potency in
suppressing diabetes in NOD mice (10) and disease onset in other animal models of
autoimmunity.
If you've got parasites or you've got chronic bacterial infections like H. pylori that's
suppressing your ability to make stomach acid, you've got the list undigested food because of the H. pylori that's affecting your gut barrier creating leaky gut, therefore allowing the immune system to get under attack and create
autoimmunity.
Nutritional deficiencies or imbalances as well as exposures to various chemicals, drugs and toxins present a continual immunological challenge which can
suppress immune function, especially in those animals genetically susceptible to immune dysfunction (immune deficiency,
autoimmunity, allergies).