Sentences with phrase «suppresses tumorigenesis»
«In the absence of catastrophic DNA damage these low levels of p53 were enough to suppress tumorigenesis.»
https://www.salk.edu/
Can MDM2 itself be inhibited in unique ways to reactivate TP53 and suppress tumorigenesis?
Not exact matches
Studies in the last two decades revealed that telomeres and telomerase have dual functions in suppressing and facilitating tumorigenesis: In the adult human, the activity of telomerase is mostly restricted to the stem cells and is absent from the vast majority of human cells.
Moreover; the PI3K / AKT pathway also can contribute to melanoma tumorigenesis through mutations or loss in PTEN and dysregulation in expression of AKT, which positively regulates the G1 / S phase progression in cell cycle, suppresses apoptosis and promotes cellular survival.
Molecular Targeting of TRF2 Suppresses the Growth and Tumorigenesis of Glioblastoma Stem Cells.
Lozy F, Cai - McRae X, Teplova I, Price S, Reddy A, Bhanot G, Ganesan S, Vazquez A, Karantza V. ERBB2 overexpression suppresses stress - induced autophagy and renders ERBB2 - induced mammary tumorigenesis independent of monoallelic Becn1 loss.
The paper, Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis, http://cancerres.aacrjournals.org/content/76/8/2115, April 2016 found that colorectal cancers associated with B. fragilis could be suppressed, not just by eradicating the microorganism, BUT ALSO BY REDUCING INFLAMMATION.