Tumors also release microparticles containing PS, ultimately
suppressing immune response to the tumor by keeping the host's immune system busy fighting particles and dead cells.
Not exact matches
Scientists have found a way
to target elusive cells that
suppress immune response, depleting them with peptides that spare other important cells and shrink
tumors in preclinical experiments, according
to a paper published online by Nature Medicine.
These types of engineered
tumors are much more difficult
to treat than human
tumors implanted in mice, because they
suppress the
immune response against them.
SHP2 also
suppresses T - cell activity against growing
tumors through regulation of the adaptive
immune response by binding
to PD - 1 and dephosphorylating CD28 and the protein LCK.
Based on this data, researchers concluded that learned helplessness in rats who couldn't escape the shocks must have
suppressed the
immune response known
to fight off cancer cells in
tumors of this sort.