Sentences with phrase «suppressor for»

Though he left boeing at age 31, after inventing / developing a hydraulic resounce suppressor for the 747 or was at least part of the team that developed the suppressor.

If you want a modification like a suppressor for those stealthy robberies or an extended magazine to mow down heavily armored SWAT agents, you'll have to cough up even more cash.

Magnum bullets or a suppressor for your pistol?

He may be no fan of cell phones, but he's a master craftsman, recycling used auto parts to build a sound suppressor for the assassin's rifle.

Replacement small grain flow suppressor for NutriMill Plus grain mill.

Not exact matches

In addition to holding the Ingram itself, its swat case has room for three spare clips (totaling 96 rounds of 9 mm, or 48 rounds of the awesome.45 caliber ammunition), a flash suppressor (whose weight also stabilizes the barrel and keeps it from «climbing» during full automatic firing), a loading tool and cleaning accessories.

The red suppressor is for small grains and the gray suppressor is for large grains such as beans.

(a rifle having at least 2 of: folding or telescoping stocks, pistol grip, bayonet mount, flash suppressor or threaded barrel for one, barrel attached grenade launcher.

For a variety of male mammals, vasectomy (sometimes reversible) and castration are the most common contraceptive methods, though there has been success in some species with hormone suppressors called GnRH agonists.

«Combination therapy strengthens T cells in melanoma pre-clinical study: Findings have implications for treating tumors lacking tumor suppressor gene PTEN.»

Looking to target a key pathway in order to interfere with the processes that lead to tumor spread, a research team led by Irwin H. Gelman, Ph.D., of Roswell Park Cancer Institute (RPCI) has identified a new suppressor of cancer metastasis that may point the way toward development of more effective treatments for prostate cancers and other malignant solid tumors.

One known miR - 182 target is CHEK2, a known tumor suppressor and suspected genetic risk factor for high - tension glaucoma.

Inherited mutations of the tumour suppressor gene CDKN2A are the strongest known risk factors for familial melanoma and mutations in this gene also increase the risk of other cancers.

A UNC Lineberger Comprehensive Cancer Center discovery of just how a certain tumor suppressor molecule works to prevent tumor growth could lead to a personalized treatment approach for colon cancer.

The researchers found that high expression of the tumor - suppressor ZMYND11 is associated with longer survival for patients with triple - negative breast cancer.

The findings provide proof of principle that restoring the function of a single tumor suppressor gene can cause tumor regression and suggest future avenues for developing effective cancer treatments.

In their research on young mice, for instance, all the subjects died when they were infected with the Nodamura virus, but when Ding's researchers removed the suppressor protein called B2 from the virus, the infected mice began producing huge armies of the virus - attacking siRNAs and lived, unaffected by the otherwise lethal infection.

«Our data strongly suggest that KIF1Bβ, which is localized on chromosome 1p36, might be such a neuroblastoma tumor suppressor gene,» says principal investigator Susanne Schlisio at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet and Assistant Member at the Ludwig Institute for Cancer Research in Stockholm, Sweden.

The studios use computer - controlled scratch suppressors when preparing old music for release on CDs.

After working on the genetics of yeasts during a Ph.D. in pharmacy at the University of Valencia, Gil moved to the United States for a postdoc on human suppressor genes.

BRCA1 and 2, genes whose proteins are supposed to work as tumor suppressors and also repair DNA damage, were the first known risk factor genes for familial breast cancer as well as ovarian and other cancers.

They tested these drugs one at a time for lethal interaction with 112 different tumor - suppressor gene mutations in human cancer cells growing in the lab.

«We knew that Smchd1 was an epigenetic suppressor — a factor that switches off genes that are unnecessary for that particular cells» function — but we were in the dark about where and how it was acting on the DNA.»

«This study provided a conceptual framework for the discovery of «traceable» targets in cancers harboring specific tumor suppressor deficiencies.»

«Identifying targets essential to cell survival in tumor suppressor genes has long been an investigational goal with the aim of offering cancer - specific vulnerabilities for targeted therapy,» said Ronald DePinho, M.D., professor of Cancer Biology, MD Anderson president, and senior author for the Nature paper.

By searching for gene deletion patterns in cancer through a concept the investigators call «synthetic essentiality,» the team identified a synthetic essential gene known as chromatin helicase DNA - binding factor (CHD1) as a therapeutic target for prostate and breast cancers lacking a tumor suppressor gene called phosphatase and tensin homolog (PTEN).

«We reasoned that this retained synthetic essential gene might be required for cancer - promoting actions when the cancers lose specific tumor suppressor genes.»

They propose that normal tissue becomes primed for cancer when oncogenes are activated and tumor suppressor genes are silenced or lost, but that cancer develops only when a cell in the tissue reverts to a more primitive, embryonic state and starts dividing.

A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes.

«Videos of these confrontations showed that the fish injected with the methylating agent were much more likely to be the winners, while those receiving the methylation suppressor typically lost the fight for dominance.

If the targeted RNA encodes a tumor suppressor protein, as scientists have found for some, the ultimate effect of the microRNA could be to promote cell — and tumor — growth.

In each pair, one male was injected with a methylating agent while the other received a methylation suppressor, and the two fish fought for dominance.

For example, they produce proteins called cytokines that tell infection - fighting immune cells to back off and recruit «suppressor» cells directly from the bone marrow that help cancel the immune attack.

Center for Elephant Conservation, elephants have 38 additional modified copies (alleles) of a gene that encodes p53, a well - defined tumor suppressor, as compared to humans, who have only two.

«This function for BAI1 may have implications for cancer biology, since MDM2 can function as an oncogene by degrading important tumor suppressors like p53.»

While it's too early to grasp all the factors involved, elite suppressors should help us finesse the cure and eradicate AIDS for good.

Then essentially what you are looking for is suppressor mutations, things which alter other genes, which change the sensitivity of the organism for insulin.

Now, results of a new study by Johns Hopkins Kimmel Cancer Center scientists suggests a powerful role for the protein in normal breast cells, acting as a tumor suppressor that halts abnormal cell growth.

They found that while elite suppressors often have the rare set of genes that code for HLA - B, those genes are «neither necessary nor sufficient» for controlling the virus.

Recently, for instance, the team found a group of elite suppressors with elevated levels of p21, a cancer - fighting protein that disrupts key aspects of the HIV life cycle in the lab.

2003 Chinese company Shenzhen SiBiono GeneTech gains approval for treating head and neck cancer with Gendicine, a modified adenovirus carrying a tumour - suppressor gene.

Now, researchers at The Wistar Institute have discovered how STAT3 behaves in immature myeloid cells known as myeloid - derived suppressor cells (MDSCs), and they believe they have found the basis for a much more effective method of using STAT3 inhibitors to stop cancer progression in its tracks.

Pten (short for phosphatase and tensin homolog) is a tumor suppressor that is defective in about 20 - 25 percent of all patients with cancers.

«A new tumor suppressor gene for breast cancer in mice.»

The current discovery that MAX acts as a tumor suppressor in lung cancer provides evidence that an aberrant SWI / SNF - MYC / MAX network is essential for lung cancer development.

Importantly, about 70 percent of LFS families have a mutation in their version of the gene TP53, which is the blueprint for protein p53, well known by the nickname «the tumor suppressor.»

It has been known for a number of years that PREX2 is a GTP / GDP exchange factor that inhibits a tumor suppressor protein called PTEN, and that this process can promote tumorigenesis by activating the PI3K signaling pathway (Fine et al., 2009; Hodakoski et al., 2014; Figure 1A).

«Through further functional studies we found that myosin IIa is also required for activation of the main guardian of the genome — a tumor suppressor protein called p53.»

LA JOLLA, CA — A close collaboration between researchers at the Salk Institute for Biological Studies and the Institute for Advanced Study found that the tumor suppressor p53, long thought of as...

As a powerful tumor suppressor, p53 turns on genes that either halt cell division to allow time for repair of damaged DNA or, when all rescue attempts prove futile, to prevent cells with genetic defects from dividing, as this would fuel the development of cancer.