The mutations may be in genes governing some aspect of the immune system but they might also be in tumor
suppressor genes whose job it is to seek out and destroy cancerous cells, genes that control cell division, genes that control normal cell death, and other types as well.
Applying their technique to head and neck cancers, they've discovered seven new tumor -
suppressor genes whose role in cancer was previously unknown.
«This study shows that NF - kB might coordinate a network of immune -
suppressor genes whose products enable tumor cells to evade adaptive immunity,» he adds.
Not exact matches
BRCA1 and 2,
genes whose proteins are supposed to work as tumor
suppressors and also repair DNA damage, were the first known risk factor
genes for familial breast cancer as well as ovarian and other cancers.
In addition, some CFSs overlap tumor
suppressor genes,
whose inactivation further fuels tumor progression.
Dr. Verma's major research interests are oncogenes and tumor
suppressors, normal
genes whose alteration can cause cancer, and the development of techniques for
gene therapy.