Their study explained changes in the assembly of a large
supramolecular protein complex involving RNA polymerase.
Not exact matches
Back then, most researchers were working on making
supramolecular systems that were able to perform either linear or rotational motions — «but Jean - Marie said, when I arrived in the lab, «You know, the most important mechanical motion in the world is the coiling motion of the
proteins in the biological world,»» Barboiu recalls.
As the leader of a research group devoted to biomimetic
supramolecular chemistry, he creates «unnatural» molecules with defined, predetermined shapes that closely resemble the major biological polymers,
proteins and DNA, found in cells.
The PNNL scientists found that RNAP exists as a large
supramolecular complex whose
protein composition substantially changes in response to growth conditions.
This will require the cooperative efforts of researchers across a wide range of disciplines: scanning probe microscopy,
supramolecular chemistry,
protein engineering, self assembly, robotics, materials science, computational chemistry, self replicating systems, physics, computer science, and more.
London, UK About Blog BMC Biochemistry is an open access, peer - reviewed journal that considers articles on all aspects of biochemical processes, including the structure, function and dynamics of metabolic pathways,
supramolecular complexes, enzymes,
proteins, nucleic acids and small molecular components of organelles, cells and tissues.