The latter could be caused by the former, but also by other conditions such as progressive
supranuclear palsy (a rare brain disorder that destroys nerve cells) or multiple system atrophy (a degenerative condition originating in parts of the brain).
They include some forms of frontotemporal dementia, as well as progressive
supranuclear palsy (PSP), a movement disorder that can also affect mood and thinking.
The scientists say a clinical trial using salsalate to reduce tau levels in progressive
supranuclear palsy, another tau - mediated neurological condition, has already been initiated.
Non-fluent progressive aphasia, depression, and OCD in a woman with progressive
supranuclear palsy: Neuroanatomical and neuropathological correlations
This case highlights the fact that frontotemporal lobar degeneration / progressive
supranuclear palsy (FTLD / PSP) and other «tauopathies» represent a complex group of neurodegenerative disorders that may masquerade for many years as refractory psychiatric disorders.
Progressive
supranuclear palsy: Diagnosis, pathology and therapy, eds Tolosa, Duvoisin and Cruz - Sanchez.
Magnetic resonance imaging (MRI) has been used to help researchers pin down the nature of a rare but debilitating and ultimately fatal disorder known as progressive
supranuclear palsy (PSP).
Elevated tau is associated not just with Alzheimer's but with a range of lesser - known neurodegenerative diseases, such as progressive
supranuclear palsy and corticobasal ganglionic degeneration.
Progressive
supranuclear palsy has no cure and is hard to diagnose.
The illness was later renamed progressive
supranuclear palsy (PSP) to describe the weakness or paralysis (palsy) patients develop when brain areas that control eye movements are affected by the syndrome — which produces the classic symptom of motionless eyes described by Dickens.
As a result, tau accumulates inside cells to form the infamous clumps that are considered hallmark pathology in neurodegenerative disorders such as Alzheimer's and progressive
supranuclear palsy.
He had progressive
supranuclear palsy for four years, according to the East Hampton Star.