Sentences with phrase «surface of a human cell»

Not exact matches

The human body has about 1,000 kinds of such receptors, structures on the surface of cells, which let the body respond to a wide variety of chemical signals, like adrenaline.

For the first time, researchers used human cells to build a model of the surface of the eye that's equipped with a fake eyelid that mimics blinking.

But the London researchers have shown a few small changes in the shape of a surface protein were all it took to enable the bird version of Spanish flu to bind onto human cells.

Researchers studied the structure of proteins from one strain of the H7N9 virus that caused the outbreak and tested how strongly one of the proteins bound to molecules on the surfaces of bird and human cells.

Researchers at Harvard T. H. Chan School of Public Health and the Broad Institute have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

Scientists have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

Currently, seasonal flu vaccines are designed to induce high levels of protective antibodies against hemagglutinin (HA), a protein found on the surface of the influenza virus that enables the virus to enter a human cell and initiate infection.

Since then, evidence has emerged that the crucial human proteins are HLA antigens, proteins that appear on the surfaces of cells and vary from person to person.

MERS CoV (CoV stands for coronavirus) has on its surface an array of spike - shaped proteins that bind to host cells — specifically to receptor proteins called DPP4 on the surface of cells that line human airways.

A radio - labeled human antibody binds to the viral gp41 protein expressed on the surface of the HIV - infected human lymphocyte and the cell is killed by alpha radiation delivered by the antibody.

They found that adding a hydrocinnamoyl ester on to the sugar stabilized the ligand and kept it close to the surface of the antigen - presenting cell, thereby enhancing its ability to dock with and stimulate human iNKT cells.

The health of the human vagina depends on a symbiotic / mutually beneficial relationship with «good» bacteria that live on its surface feeding on products produced by vaginal skin cells.

With gene - editing tools such as CRISPR, scientists can now eliminate immune - provoking sugars from the surface of pig cells, introduce human genes that regulate blood coagulation to prevent dangerous clots, and snip out viral sequences that some fear could infect a human host.

The use of cell surface markers to isolate specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA expression is a powerful new way enabling the study of small cell niches in nongenetically modified animal models and human tissue.

The researchers are the first to grow human vaginal skin cells in a dish in a manner that creates surfaces that support colonization by the complex good and bad communities of bacteria collected from women during routine gynecological exams.

Then, by placing surface proteins of each HCV virus onto these pseudoviruses, the researchers were able to efficiently infect human cells with the HCV strains in tissue culture.

A study of the way malaria parasites behave when they live in human red blood cells has revealed that they can rapidly change the proteins on the surface of their host cells during the course of a single infection in order to hide from the immune system.

In human medicine EGFR is frequently used as the target of cancer immunotherapy because many cancer cells bear this receptor on their surface.

«Making the movements of HIV visible so that we can follow, in real time, how surface proteins on the virus behave will hopefully tell us what we need to know to prevent fusion with human cells — if you can prevent viral entry of HIV into immune cells, you have won,» says Dr. Blanchard, who is also associate director of Weill Cornell's chemical biology program.

The Discher Lab has since shown that a protein on human cells called CD47 functions as a «marker of self» by interacting with a protein on the surface of macrophages called SIRPA.

These organoids form all of the cell types present in human intestine, but they grow as cysts surrounded by thick extracellular matrix gels with their «apical» cell surface (which is normally exposed to the content of the gut) facing an enclosed lumen.

Dr. Shiloh and his team currently are working to discover the human cell - surface receptors for Mtb that are involved in the bacteria's M - cell translocation, as well as to determine the exact machinery used by the cell to move the bacteria from the surface to the bottom of the cell.

He then injected human endothelial cells into the collagen structures of blood vessels to recolonise the surfaces of blood vessels.

Researchers at the Babraham Institute and the Karolinska Institute report today in Cell Stem Cell that they have identified a set of proteins (molecular «flags») that are present on the surface of either naïve or primed human embryonic stem cells.

The new coronavirus latches onto a protein called dipeptidyl peptidase 4, or DPP4, which decorates the surface of many cells, including some in human airways and kidneys, Bart Haagmans of Erasmus Medical Center in Rotterdam, the Netherlands, and colleagues report in the March 14 Nature.

Researchers have identified a set of molecular «flags» that are present on the surface of human stem cells.

The protein LecA on the surface of the bacteria binds to sugar on special lipid molecules, so - called Gb3 lipids, which are present in the outer membrane of human cells.

Human - associated bacteria disperse into and throughout the built environment by three primary mechanisms: (1) direct human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden partiHuman - associated bacteria disperse into and throughout the built environment by three primary mechanisms: (1) direct human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden partihuman contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden partihuman skin cells, hair and other bacteria - laden particles.

Weiss A, Imboden J, Shoback D, Stobo J. Role of T3 surface molecules in human T - cell activation: T3 - dependent activation results in an increase in cytoplasmic free calcium.

HLA (human leukocyte antigen)- markers on the surface of a body's cell that identify the cell as one's own (as opposed to a foreign cell) and prevent the immune system from attacking itself.

Further research uncovered a broad spectrum of cell surface stem cell markers (e.g., CD133, CD44, and CD24) that allow the identification of CSCs in human solid tumors, including brain, breast, prostate, pancreas, liver, ovary, skin, colon cancers, and melanoma (3 - 6)(Figure 1 based on 7).

Synthetic peptide - acrylate surfaces for long - term self - renewal and cardiomyocyte differentiation of human embryonic stem cells.

Epithelial cells line the cavities and surfaces of structures in the human body.

Clone 1022 cells ezpress human CD4 protein on the cell surface and can be infected by most isolates of HIV.

Characterization and functionality of cell surface molecules on human mesenchymal stem cells.

Proteins on the surface of both the Plasmodium sporozoite and human host cells are likely to be important in this journey, but little is known about the exact interactions which occur.

I started my PhD in the Cell Surface Signalling Group in 2013 and have since been investigating how Plasmodium falciparum parasites, the causative agent of the most severe form of human malaria, interact with their human host.

This is a derivative of the TZM - bl cell line, engineered by lentiviral transduction to stably express human FcγRIIb on the surface.

This is a derivative of the TZM - bl cell line, engineered by lentiviral transduction to stably express human FcγRI on the surface.

This is a derivative of the TZM - bl cell line, engineered by lentiviral transduction to stably express human FcγRIIIa on the surface.

He isolated the genes encoding proteins that confer immunological identity to the two main types of cells in the human immune arsenal: the CD4 protein, which dots the surface of helper T cells, and the CD8 protein, which adorns killer T cells.

The most potent of these, known as effector memory T cells, are activated by a group of proteins known as human leukocyte antigens (HLAs) on the surface of endothelial cells lining the donated organ's blood vessels.

A study from Dr. Dusty Miller's laboratory indicates that Jaagsiekte sheep retrovirus (JSRV) infects both sheep and human cells cultured outside the body and does so by attaching to a receptor on the surface of lung cells.

Human amniotic membrane (AM), the innermost layer of the placenta is the most common substrate used for both in vitro cultures and as a vehicle for transfer of cells during transplantation, due to its structural similarities to the ocular surface, as well as its biological and functional properties.

Human MSCs are defined by positive expression of the cell surface antigens CD73, CD90, CD105 and by absence of expression of hematopoietic antigens, including CD11b or CD14, CD34, CD45, CD79 or CD19, and HLA - DR.

Miller's group, including postdoctoral fellow Dr. Sharath Rai, graduate student Vladimir Vigdorovich and collaborators at the National Cancer Institute, identified the human version of the viral receptor, a cell - surface protein called HYAL2 that has been implicated in lung cancer.

Colin Barnstable, DPhil (M Club) Chair, Neural and Behavioral Sciences «Production of monocolonal antibodies to group A erythrocytes, HLA and other human call surface antigens — new tools for genetic analysis» Cell, 1978 2,020 citations, Web of Science, April 1, 2017

A Postdoctoral Research Associate Position is available funded by the Wellcome Trust, to study the nanoscale organisation of human immune cell surfaces by super-resolution fluorescence microscopy.

Inventors at MUSC have identified a unique human CD4 + T cell population that expresses high levels of surface CD26, termed CD26high T cells, which mediate durable antitumor immunity in vivo, and have immediate clinical relevance for designing new vaccines and cellular therapies.

The folds in the human brain form sulci (grooves) and gyri (ridges), adding to its surface area to maximize the number of cells that can pack into our skulls, and increasing the quantity of information we can process.