The microglia then «summon» peripheral immune cells from other parts of the body, and these cells proceed to attack the protective myelin sheaths that
surround the axons — or nerve fibers — in the brain.
Several neurological disorders, including autism and schizophrenia, are thought to be driven in part by the failure of myelin to properly
surround axons during development.
The speed of transmission depends on several factors, including the diameter of the axon and the thickness of the electrically insulating myelin sheaths that
surround the axons.
One clear characteristic of MS is scarring of myelin, the protective substance
surrounding the axons that extend from nerve cells.
Recent research suggests one benefit of environmental enrichment at the cellular level: it repairs brain myelin, the protective insulation
surrounding axons, or nerve fibers, which can be lost because of aging, injury or diseases such as multiple sclerosis.
Not exact matches
In the AIDP variant of Guillain - Barré syndrome, the focus of the autoimmune attack is the myelin sheath, a layer of insulation that
surrounds nerve
axons, similar to the insulation around the wires of an electric cable.
A few microscopic techniques can focus light deep into the intact brains of dead animals to study its structure without damaging the
axons, but much of this light is scattered away by the fatty lipid membranes that
surround individual cells, making the technique less than perfect.
This
surrounds and protects the
axons of the neurons, helping nerve signals to propagate rapidly.
OLs formed before tamoxifen injection are red, newly - forming OLs have a yellow «cell body» containing the nucleus
surrounded by a green «bundle of sticks» which are short stretches of myelin wrapped around thread - like
axons.
Even more surprising, these cells appear to stimulate
axon myelination in the
surrounding neurons.»
Building up the
axons» insulation is the responsibility of the
surrounding Schwann cells.
Through dozens of nerve biopsies, they did discover a key difference in AMAN from traditional GBS in that the attack focuses on the nerve
axon, rather than the
surrounding myelin.
There are two categories of CMT: those caused by the loss of
axons in the peripheral nerves (CMT2) and those characterized by a malfunction in the Schwann cells that make up the myelin sheath, the protective coating that
surrounds the nerve fibers and allows them to conduct nerve signals at high speeds (CMT1).
MS is a debilitating neurological disease caused by the destruction of oligodendrocytes, cells that build the myelin sheaths that
surround the signal transmitting
axons of neurons.
Myelin is a specialized structure that
surrounds large
axons and permits rapid conduction of signals.
But the precise function of PMP22, a major component of the myelin sheath that
surrounds and insulates peripheral nerve cell
axons, has been unclear.
When a nerve cell is activated, it sends an electrical impulse down its
axon to the terminal, which stimulates a vesicle within the terminal to migrate to the terminal's
surrounding membrane.