However, because of the aggressive way glioblastomas
invade surrounding brain tissue, it is impossible to remove all parts of the tumors, and the cancer eventually returns and spreads.
Selectively expressed on GBM and absent
on surrounding brain tissue, the interleukin - 13 receptor α chain variant 2 (IL13Rα2) was identified as a potential target for therapy for GBM two decades ago.
Cerebral cavernous malformations (CCMs) are clusters of dilated, thin - walled blood vessels that can lead to seizures or stroke when blood leaks into
the surrounding brain tissue.
The immune system's attack on the cyst can cause
the surrounding brain tissue to swell with inflammation.
But it also damages neurons that don't lie directly in its path, because it is trailed by a pressure wave that transfers the energy of bullet into
the surrounding brain tissue.
The treatment may cause injury to
the surrounding brain tissue and the nerves associated with the eyes.