Melanoma cells become drug resistant by using
surrounding healthy cells to provide a «safe haven» from treatment, according to new research published in Cancer Cell.
The team's system has another advantage: CIK cells burrow deep into tumor tissue; that means the virus shouldn't harm
surrounding healthy cells.
The Kanzius RF Machine transmits focused radio waves to these nanoparticles, which respond by releasing heat and incinerating infected cells while leaving
the surrounding healthy cells intact.
In a bid to progress beyond the shotgun approach to fighting cancer — blasting malignant cells with toxic chemicals or radiation, which kills
surrounding healthy cells in the process — researchers at the Harvard - MIT Division of Health Sciences and Technology (HST) are using nanotechnology to develop seek - and - destroy models to zero in on and dismantle tumors without damaging nearby normal tissue.
Not exact matches
But in the following hours and days, the body's self - defense mechanisms backfire: White blood
cells come in to clean up dead tissue, which causes massive inflammation, which in turn triggers
healthy cells in the
surrounding tissue to self - destruct in a process called apoptosis.
This early stage research will explore how the virus targets stem
cells and provide the starting point to develop new treatments that seek out the tumour and spare the
surrounding healthy brain tissue.
One reason for this is that the tumour
cells invade
surrounding,
healthy brain tissue, which makes the surgical removal of the tumour virtually impossible.
Within that sting lies a peptide called chlorotoxin, which has an unusual property — it sticks strongly to tumour
cells while ignoring
surrounding healthy tissue, by binding to a cancer - specific protein called matrix metalloproteinase - 2.
But working with human smooth muscle
cells isolated and grown from the
healthy parts of airway tissue
surrounding excised tumors, Benjamin Kalbe and his colleagues applied a large number of odor molecules and watched two of them activate the muscle
cells.
Writing in 2014 in the European Journal of Neuroscience, Leuner and colleagues reported that in rats with symptoms of postpartum depression (induced by stress during pregnancy, a major risk factor for postpartum depression in women), nerve
cells in the nucleus accumbens atrophied and showed fewer protrusions called dendritic spines — suggesting weaker connections to
surrounding nerve
cells compared with
healthy rats.
Once inside, researchers found that the antibodies zeroed in on their targets — viral antigens — and the radioisotopes destroyed nearby cancer
cells without damaging
surrounding healthy tissue.
Cancer
cells rely on the
healthy cells that
surround them for sustenance.
Three new studies suggest ways to home in on cancer
cells during treatment, leaving
surrounding healthy tissue unharmed.
The resulting compound works by a unique mechanism of action unlike any drug currently used in the treatment of cancer, and it destroys replicating and nonreplicating malignant
cells while minimizing damage to
surrounding,
healthy cells.
They believe the mutated gene causes cancer by triggering cytoskeleton malfunction, which allows the cancer
cells to move more quickly than normal
cells, essentially invading the
surrounding healthy tissue.
The relatively small number of such
cells in a youthful tissue is so small as to be harmless, but after decades of accumulation, the number becomes large enough that their abnormal metabolic state begins to pose a threat to
surrounding,
healthy tissues.
Cancer
cells, through the protein - destroying enzyme, matrix metalloproteinase squeeze their way into
healthy cells and destroy
surrounding tissue.
Abnormal
cells are created, forming tumors which invade
surrounding healthy tissue.