Sentences with phrase «surrounding tumor tissue»

Not exact matches

The surgeons removed a softball - sized tumor along with skin and muscle tissue surrounding it.

Understanding how margin length decreases from surgery to pathology — because of how the removed tissue shrinks and tumor cells invade surrounding tissues — can lead to better surgical margin planning and in turn a better prognosis, said corresponding author Milan Milovancev, a board - certified veterinary surgeon at OSU's College of Veterinary Medicine.

To migrate from a primary tumor, a cancer cell must first break through surrounding connective tissue known as the extracellular matrix (ECM).

If the disease requires treatment and isn't widespread, he will use focal brachytherapy — implanted radioactive seeds — to irradiate only the tumor, sparing the surrounding tissue.

In 2002 scientists showed that cytomegalovirus, or CMV, was active in the brain tumors but not the surrounding healthy tissue of all 27 patients they tested who had glioblastoma multiforme.

It would be interesting to see the effect that rapamycin has on those tumors and the surrounding tissue.»

Radiation therapy and chemotherapy that can destroy tumors also can damage surrounding healthy tissue.

In a bid to progress beyond the shotgun approach to fighting cancer — blasting malignant cells with toxic chemicals or radiation, which kills surrounding healthy cells in the process — researchers at the Harvard - MIT Division of Health Sciences and Technology (HST) are using nanotechnology to develop seek - and - destroy models to zero in on and dismantle tumors without damaging nearby normal tissue.

However, because of the aggressive way glioblastomas invade surrounding brain tissue, it is impossible to remove all parts of the tumors, and the cancer eventually returns and spreads.

Molecular Breast Imaging (MBI) is a supplemental imaging technology designed to find tumors that would otherwise be obscured by surrounding dense breast tissue on a mammogram.

But working with human smooth muscle cells isolated and grown from the healthy parts of airway tissue surrounding excised tumors, Benjamin Kalbe and his colleagues applied a large number of odor molecules and watched two of them activate the muscle cells.

Tumors are acidic, and they secrete acids into the surrounding tissue.

Increased stiffness also occurs in cancer, where tumors are typically stiffer than the surrounding tissue.»

The scientists then devised a novel nanoparticle that selectively delivers genetic material to a tumor and prevents side effects in surrounding healthy tissues.

Instead, tumors should be considered complex tissues in which the cancer cells communicate with the surrounding cellular microenvironment and evolve traits that promote their own survival.

Previous cancer studies had shown that by injecting tumors with magnetic nanoparticles made of iron oxide — «essentially rust, with well - tuned magnetic properties,» Anikeeva says — then exposing them to rapidly alternating magnetic fields, excited nanoparticles can be used to heat and destroy cancer tumors while leaving surrounding, healthy tissue intact.

Instead, tumors should be considered as complex tissues in which the cancer cells communicate directly and indirectly with the surrounding cellular microenvironment and evolve traits that promote their own survival.

Therapeutics targeted to tumors, for example, should be delivered only to the tumor and not to surrounding tissues.

This method measures the activity of protein - cutting enzymes called endoproteases, which are made by tumors to help recruit blood vessels and invade surrounding tissues so the cancer can grow and spread.

This process requires a fundamental change in the character of cells within the primary tumor, insofar as members of a localized cell mass must be converted into actively migrating cells that invade into the surrounding tissue and blood vessels, and finally settle in distant tissues.

So a drug that blocks DDR2 from binding with collagen won't destroy the tumor, but it could inhibit the invasion of these tumors into surrounding tissue and reduce metastasis.

The current clinical trial uses information of air movement from existing 4D CT data and «some equations,» says Vinogradskiy (diplomatically) to calculate lung function in tissue surrounding tumors.

A few years ago Peperstraete stumbled on an article in a science journal about medical researchers using crossed laser beams to image and heat tumors in a patient without disturbing any of the surrounding tissue.

For this purpose, they use certain enzymes, proteases that break down the tissue surrounding the tumor, thus opening the way for tumor cells to reach blood or lymphatic vessels.

The team's system has another advantage: CIK cells burrow deep into tumor tissue; that means the virus shouldn't harm surrounding healthy cells.

Areas surrounding tumors and inflammations are usually slightly more acidic than areas surrounding healthy tissue, a phenomenon possibly linked to the aggressiveness of tumors.

According to McKenna, this makes it a prime target for anti-cancer drugs that would cause little or no side effects to healthy tissue surrounding the tumor.

When compared to surrounding healthy tissues, it's hoped that contrast enhanced MRIs will reveal the shape and nature of any tumors present.

Stereotactic body radiation is a newer type of radiation therapy which delivers higher doses of radiation to the tumor but spares the surrounding tissue.

But many tumors do not significantly differ from surrounding healthy tissues with contrast enhanced MRI and so evade easy detection.

As the irradiated area is smaller, the drug delivery is confined to the targeted area, resulting in less damage to healthy tissue surrounding the tumor.

Glycolysis» waste product, lactic acid, might also make surrounding tissue more vulnerable to a tumor's infiltration.

2004: IMRT (Intensity Modulated Radiation Therapy) Program began to deliver high - precision radiation that conforms to the three dimensional shapes of tumors and delivers higher and well defined doses of radiation to tumors, and even specific areas within tumors, while minimizing radiation to surrounding normal tissue.

If he can determine how to speed up engulfment of dead tumor cells from brain tissue, it is his hope to reduce the harmful inflammation that causes death of surrounding neurons.

Treatment of malignant glioma using gene transfer modalities typically consists of surgical debulking of the tumor mass followed by the administration of the viral vectors into the brain tissue surrounding the tumor cavity.

It is based on whether the tumor is local to its area of origin, or has spread to the lymph nodes or other parts of the body — as well as how deeply it has invaded surrounding tissues.

Whereas the tumor is in constant competition with the surrounding tissue, little is known about the mechanics of this interaction.

Dr. Jain is regarded as a trailblazer in the study of tumor microenvironment, examining in detail the notion that the relationships between tumors and their surrounding non-tumor tissue — including blood vessels — are essential determinants of disease progression, therapeutic efficacy, and patient prognosis.

The surgery can be «open» — meaning, the doctor will make a large cut to remove the tumor, surrounding healthy tissue, and nearby lymph nodes all at once — or «minimally invasive,» in which a surgeon can use special tools to remove the growths by making a few smaller cuts.

Though I suppose that at the beginning tumor is slightly more alkaline than surrounding tissue, then it grows and develops acidic shell with «proton pump» mechanism, keeping its core even more «live» (alkaline).

When a tumor outgrows its blood supply, it sends a sign to surrounding tissues to deliver more nutrients and oxygen.

When the team first examined the microbial composition of intestinal biopsies, they saw the bacterial strains in the tumors and surrounding tissues of colon cancer patients differed from the bacterial strains in the gut of healthy individuals.

«Tumor growth, invasion, and metastasis are multistep processes» that includes not just cell proliferation, but invasion through the surrounding tissue, and «migration through basement membranes» to reach the bloodstream before the tumor can establish «new proliferating colonies» of cancer cTumor growth, invasion, and metastasis are multistep processes» that includes not just cell proliferation, but invasion through the surrounding tissue, and «migration through basement membranes» to reach the bloodstream before the tumor can establish «new proliferating colonies» of cancer ctumor can establish «new proliferating colonies» of cancer cells.

They tend to invade surrounding tissues and metastasize (spread to distant tissues) even when the primary tumor is very small.

ISS are locally invasive tumors that penetrate through surrounding tissue with tumor «roots».

After a thorough examination, your veterinarian will remove the tumor alone or choose to remove the surrounding tissue, lymph nodes and mammary glands.

Normally fatty tumors sit in a little pocket or fibrous case separated from surrounding tissues, but very rarely fatty tumors penetrate into the surrounding tissues, especially into muscle.

The best option will depend on the size of the tumor, how it is attached to the surrounding tissue, and whether or not it has spread to other parts of the body.

Benign tumors rarely ulcerate or bleed but large tumors may have physical effects by pressing on the surrounding tissues or structures, or may lose some of their blood supply causing parts of them to die.

Large tumors may have physical effects by pressing into the surrounding tissues.