Sentences with phrase «survival factor for»

These factors include chemokine (C - X-C motif) ligand 12 (CXCL12), a chemokine produced by bone marrow mesenchymal cells that functions as a chemoattractant and survival factor for cells bearing the chemokine (C - X-C motif) receptor 4 (CXCR4), and insulin - like growth factor 1 (IGF - 1), a factor that is stored in the bone matrix and released during osteolysis (28).

Not exact matches

«Reducing time to defibrillation is the most important factor for increasing survival in [out - of - hospital cardiac arrest]», noted the study authors.
One factor is «the law of survival of the fittest» — those who remain, who are still actually going to Church, are those who actually believe what is taught and are extremely grateful for the lead given by John Paul II.
The economic factors of life in many primitive cultures dictated that those members of the tribe who could not share the burden of the struggle for survival were not carried by the tribe, even as revered, elderly dependents of the society.
The Daily Mirror claims Chelsea look prepared to join the running for # 50million - rated Zaha's signature after his fine form in the Premier League this season has been one of the main factors giving Palace any hope of securing survival in the top flight.
But disregarding the effect of all these different factors, you'll find the average survival rates week by week below, for extremely premature babies that received mechanical breathing help, which is necessary for survival for extremely premature babies.
In addition, researchers have recently also been able to pinpoint two additional factors that contribute to the chances of survival for a particular child: the gender and whether or not the mother received ante-natal steroids before the baby was born.
The risk factors for impaired neonatal health are high, and survival, though very low, is a tangible reality.
Like human taste buds which reward us for eating what's overwhelmingly critical for survival i.e. fats and sugars, a consideration of human infant and parental biology and psychology reveal the existence of powerful physiological and social factors that promote maternal motivations to cosleep and explain parental needs to touch and sleep close to baby.
Factor in the diapers, formula, daycare if needed and necessary starter accessories for survival.
non-specific - like lactoferrin, lysozyme and bifidus factors which either make human milk a poor medium for bacterial survival or make the intestine unsuitable for the growth of pathogenic agents.
They show for the first time that orphan genes are frequently lost and consider the factors the influence the «survival» of the young genes.
Disease - causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors.
One of the genes most often associated with anorexia nervosa codes for BDNF, a factor involved in neuron survival and neuroplasticity.
A new study published online by JAMA Oncology examines the assessment of minimal residual disease in patients newly treated for multiple myeloma as a factor in survival outcomes.
The current study identified a new role for a particular group of proteins, known as RFX transcription factors, in the development and survival of the hair cells.
In a recent study, Granger and scientists with the University of Oregon tracked the release of nerve growth factor in saliva (sNGF), finding for the first time that this protein typically linked to the survival, development or function of neurons may be an important player in understanding the body's response to stress.
It found that microRNA - 486 (miR - 486) directly targets the insulin growth - factor pathway, which is important for cell survival and proliferation.
For further research, it would be important to study how other, competing risk factors might affect survival, as elderly cancer patients with diabetes are usually diagnosed with other conditions as well.
After adjusting for other risk factors, the researchers again found an overall survival benefit for BCT compared to BCS and mastectomy.
Out - of - hospital cardiac arrest (OHCA) in the United States has low survival (8 - 10 percent), with reducing time to defibrillation as the most important factor for increasing survival.
Proteins, fatty acids, and nucleic acids are essential factors for cell survival using glutamine metabolism.
«The higher risk of tumor recurrence that we observed among African American women was reduced when controlling for those factors, suggesting that these genomic differences contribute, at least partly, to the known racial disparity in the survival of African American and Caucasian breast cancer patients.»
«The ocean is like a black box for salmon and many factors can play a role in their survival,» said O'Malley, a geneticist with the Coastal Oregon Marine Experiment Station at OSU's Hatfield Center.
The researchers then looked at emotion and survival in greater detail, examining data for the most buoyant optimists, the most despondent individuals, and patients with complicating factors like smoking.
«Nomograms offer the ability to personalize survival estimates for patients based upon a host of factors that are clinically relevant when we meet patients,» stated Carole Fakhry, MD, the study's lead author and an associate professor in the Department of Otolaryngology Head and Neck Surgery at John Hopkins University.
For years, researchers have known that race is a factor in cancer survival.
To get the most accurate results, Newcomb and the research team controlled for factors such as smoking status, family history, age and other characteristics and then conducted statistical analyses to determine potential association of NSAID use to both overall and disease - specific survival.
In the current study, a number of prognostic factors such as age, stage, comorbidity, hormonal receptor and HER2 status and differences in systemic treatments (medication after surgery) were included and considered as possible explanations for the previously reported survival differences between BCT and mastectomy.
Factors proposed for causing such low survival include immune reactions, limited trophic factors and hFactors proposed for causing such low survival include immune reactions, limited trophic factors and hfactors and hypoxia.
Metabolic risk factors did not affect 30 - day, 1 - year or 5 - year survival for liver transplant recipients.
Experts suggest that as survival rates improve, understanding racial and socioeconomic differences in pediatric populations are important factors to consider for overall health status.
A second subgroup displayed an equally bad prognosis when histopathological factors were adjusted for, while 4 others maintained comparable survival profiles.
According to Whitehead Institute researchers, protein production or translation is tightly coupled to a highly conserved stress response — the heat shock response and its primary regulator, heat shock factor 1 (HSF1)-- that cancer cells rely on for survival and proliferation.
The degree of involvement of regional lymph nodes is predictive of overall survival and is also a key factor in determining the appropriateness of adjuvant therapy and the patient's eligibility for investigational trials.
«Because degradation of photoreceptors is believed to be a major factor in retinal diseases, such as retinitis pigmentosa and Leber's congenital amaurosis, this finding, that horizontal cells are necessary for the normal survival of photoreceptor cells, is novel and significant,» says Mu.
«The addition of new reserve areas, which are effectively just a few more small islands for a few pandas, will not address the key factors that are compromising survival of wild panda populations,» Loeffler says.
The transcription factor Runx3 enhances the differentiation and survival of CD8 + resident memory T cells; enhancing Runx3 expression in responding T cells could lead to better therapies for infection and cancer.
The finding comes from the Joslin 50 - Year Medalist Study, which examines this select cohort to discover protective factors for their long - term survival.
In 2005, Joslin launched the Joslin 50 - Year Medalist Study, which examines this select cohort to discover protective factors for their long - term survival.
The expression level of CXCR4 can be used as an independent prognostic factor for disease free survival of SCLC patients [37].
Hsiou - Chi Liou and colleagues find that c - Rel, a lymphoid - specific member of the NF - kappaB / Rel family of transcriptional factors, is essential for B lymphocyte survival and cell cycle progression, [i] and that it is important for inducible cytokine and cytokine receptor expression and a key regulator of early activation and proliferation in T cells.
The trial measured modified progression - free survival (mPFS), which factors in the length of time it took for the disease to progress, death to occur, or new therapy to be started in patients who did not show a response to the treatment.
Extended survival and prognostic factors for patients with ALK - rearranged non-small-cell lung cancer and brain metastasis.
Early disease progression for chronic lymphocytic leukemia was a robust prognostic factor for worse overall survival in patients treated with chemoimmunotherapy.
She is also leading the Jersey Girl Study, which aims to evaluate predictors of pubertal markers in girls and the Women's Circle of Health Study, a study evaluating risk factors for breast cancer risk and survival in African American women.
Protein production or translation is tightly coupled to a highly conserved stress response — the heat shock response and its primary regulator, heat shock factor 1 (HSF1)-- that cancer cells rely on for survival and proliferation, according to Whitehead Institute researchers.
In some species of the genus Pseudomonas these virulence factors are important for cell detoxification, resulting in host survival.
Subgroup analyses showed trends or significant overall survival improvements for all subgroups measured, including by disease stage, ECOG score, age, and other factors.
In the multivariate analysis, when the International Prognostic Index was controlled for, the presence of a histone modifier gene mutation was an independent prognostic factor for progression - free survival (P < 0.001)(Table 1).
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