Sentences with phrase «survival pathways»
The Cosford lab employs medicinal chemistry and chemical biology approaches to probe cellular pathways that regulate cell survival pathways in deadly tumors.
sbpdiscovery.org
In addition, new small molecule drugs are being used that target important survival pathways in NHL tumor cells.
The AKT signaling pathway plays an important regulatory role in many cellular survival pathways, primarily as an inhibitor of apoptosis.
The short lived gas nitric oxide produced inside the body activates chemical pathways which relax the blood vessels and enhance the flow of blood and trigger survival pathways.
We also show that rapamycin and total mTOR silencing induces cell cycle arrest and apoptosis interfering with proliferation and survival pathways in ALK + ALCL.
These mutations drive the MAPK cancer growth and survival pathway.
«We wanted to get a better understanding of whether there are any common cell death or cell survival pathways that could be targeted in some of these diseases.»
Inhibition of the mTOR pathway interferes with essential proliferation and survival pathways in ALK + ALCL and might form the basis for a novel therapeutic strategy.
The phosphorylation and expression of Akt, a kinase regulating a second cell survival pathway, is also inhibited after treatment with calcitriol.
On a different note, coconut oil mitigates amyloid beta toxicity in cortical neurons by up - regulating signaling of cell survival pathways (Nafar, Clarke, & Mearow, 2017).
Coconut oil protects cortical neurons from amyloid beta toxicity by enhancing signaling of cell survival pathways.