These findings for scoring expression were agreed with Gillet et al., 1996 [24], who stated in their study that, moderate / strong staining of Cyclin D1 had a longer relapse - free
survival than patients whose tumors stained weakly or negatively for Cyclin D1 with a great significant difference (P = 0.007).
The MSLT - 1 trial demonstrated that patients with a positive SLN undergoing CLND had far better melanoma - specific
survival than those patients who manifested nodal recurrence either on the observation arm or after a false - negative SLN biopsy (10 - year melanoma - specific survival rates: 62.1 % vs 41.5 % and 34.4 %, respectively).
Not exact matches
In a later study of the well - being of coronary
patients, Holden (1981) reported that ownership of a pet among ninety - three
patients was the strongest predictor of
survival, stronger even
than human relationships.
Researchers from Aston Medical School in Birmingham looked at more
than 900,000
patients with high blood pressure, high cholesterol and type 2 diabetes and found marriage led to higher
survival rates.
Sara Hiom, Cancer Research UK's director of health information, said: «
Survival rates for breast cancer have been improving for more
than 20 years - eight out of ten
patients now survive more
than five years.
A team of Swedish researchers finds that early cardiopulmonary resuscitation more
than doubles the chance of
survival for
patients suffering out - of - hospital cardiac arrest.
This recommendation is based on a separate study published in The Lancet, for which Garon was the senior author, showing longer
survival than chemotherapy among
patients with any positive staining for PD - L1.
The mean
survival time for this disease, which predominantly occurs in the elderly, is less
than a year for
patients over 65 years.
While there have been improvements in the current standard treatments,
patients with glioblastoma (GBM), the most common and aggressive form of brain tumor, still suffer from a median
survival rate of only 14.6 months and 5 - year overall
survival rates of less
than 10 %.
«Moreover, our initial data suggest that subtypes of AML with a poor prognosis are likely to be sensitive to this new therapeutic approach,» she says, adding that less
than 10 percent of
patients with certain forms of AML achieve long - term
survival.
Interestingly, female
patients had 76 percent higher odds for
survival than men.
The malignancy often remains undiagnosed until the cancer has spread, leaving
patients with a bleak prognosis and a five - year
survival rate of less
than 30 percent.
«This greater
than expected
survival in older
patients selected for operative therapy is noteworthy,» said Dr. Fernandez, «especially considering that the prevalence of lung cancer is expected to increase as the population continues to grow older and more people survive into old age.»
«African - American multiple myeloma
patients have higher incidence rates and lower
survival rates
than their Caucasian peers despite this being a relatively easy - to - treat cancer.
With a three - year
survival rate of 94.39 percent for all adult kidney recipients — above the 92.62 percent national average — UCSF has more
patients on the kidney transplant waiting list
than any other U.S. transplant center.
The median
survival for
patients is 15 months, with less
than five per cent of
patients surviving beyond five years.
Although treatment has improved, the surgery rate in
patients with ductal adenocarcinoma is around 30 percent and the five - year
survival rate is less
than 20 percent.
Studies show that PD - 1 inhibitors are effective for a larger proportion of melanoma
patients than ipilimumab alone — and, in combination with that drug, they achieve a two - year
survival rate of 80 percent.
The five year disease - free and overall
survival rates for
patients with high - risk malignant germ cell tumours remains less
than 50 %, and so accurate diagnosis and monitoring is crucial to improving outcomes for
patients.
Median progression - free
survival among
patients receiving selumetinib was more
than double that of
patients receiving chemotherapy (15.9 weeks vs. 7 weeks).
Because of the high
survival rates of childhood cancer — close to 80 percent — more cancer
patients than ever are reaching adulthood and many face fertility problems.
Reports of laboratory advances have to be hedged in cautious language for the sake of
patients and their families, talking in terms of «treatment» and «
survival» rather
than «cures».
Study results show that
patients with prior knowledge of MGUS had better overall
survival (median 2.8 years)
than patients with MM who didn't know when they had MGUS (median
survival 2.1 years), although
patients with prior knowledge of their MGUS status had more coexisting illnesses.
«The significant improvement in overall
survival with pembrolizumab was remarkable given that more
than 40 % of
patients crossed over from the control arm to pembrolizumab after progression of the disease,» said Reck.
The researchers note «strong indications» that
patients»
survival after THA is improving, and that
patients undergoing THA tend to live longer
than a matched general population.
Patients who had sentinel node biopsies had significantly greater 10 - year disease - free survival rates than patients who underwent nodal obse
Patients who had sentinel node biopsies had significantly greater 10 - year disease - free
survival rates
than patients who underwent nodal obse
patients who underwent nodal observation.
Ceritinib provides longer progression - free
survival than chemotherapy in crizotinib - pre-treated
patients with non-small-cell lung cancer harbouring an ALK rearrangement, according to results of the phase III ASCEND - 5 study presented at the ESMO 2016 Congress in Copenhagen.
Patients who had surgery in sunny months — May to August — had a roughly 30 percent higher overall
survival rate or time to cancer recurrence
than did those getting surgery in the winter.
Data revealed today at The International Liver Congress ™ 2015 show that the long - term use of entecavir (ETV) or tenofovir (TDF) results in excellent 5 - year
survival for Caucasian
patients with chronic hepatitis B (CHB), with more
than 95 % of
patients surviving at 5 years and a significant proportion of deaths coming from liver - unrelated causes.
Hospitalized heart failure
patients in all age groups within the study and with all levels of ejection fraction had significantly lower rates of
survival after five years and a higher risk of re-hospitalization
than people in the United States without heart failure.
In the total
patient population, the 5 - year overall
survival rate was 95 %, although it was significantly higher in non-cirrhotic (97 %)
than cirrhotic
patients (92 %).
«Predicting
survival is far less certain for a threatened species
than for a human
patient,» wrote leaders from 10 conservation organizations in a 2009 critique (pdf).
Usually, treatment would require whole - brain radiation which is extremely toxic and the average
survival time is just 3 - 6 months from diagnosis, with fewer
than 20 per cent of
patients surviving more
than one year.
Similarly, 29
patients had low TS levels and significantly longer average
survival times (36 months)
than patients with high TS levels (15 months).
The
survival of
patients with stage T4a larynx cancer who are untreated is typically less
than one year.
Breast cancer
patients with a mutation in both copies of the NQO1 gene have a 20 % lower
survival rate 5 years after treatment
than do
patients without the mutation, according to a new study of more
than 2000 Finnish women.
Among
patients whose tumours carried EGFR mutations, and who were treated with targeted therapies, those whose tumours were also PD - L1 positive took longer to progress, and tended toward longer overall
survival than PD - L1 negative
patients.
Methylnaltrexone relieved constipation for more
than half of the
patients, but brought no additional
survival, even for those who responded to the drug's digestive effects.
A national trial involving more
than 8,000
patients has revealed that giving oxygen to stroke victims makes no difference to their recovery or chances of
survival.
Most importantly,
patients who were negative for PD - L1 expression survived around 11 months longer
than patients who were positive for PD - L1 expression (median
survival 4.79 vs 16.3 months).
He points to a study of breast cancer
patients that provides evidence that
survival has to do more with how people deal with emotions
than how they feel.
New treatments are urgently needed for these
patients, less
than half of whom currently enjoy long - term, disease - free
survival.
Some
patients given both treatments lived significantly longer (years)
than expected, while the overall median
survival increased by 59 % (2.6 months).
Patients who were taking antacids had significantly better overall
survival than those who did not take them.
Kidney dysfunction is a frequent complication affecting more
than 50 percent of all cancer
patients, and is directly linked to poor
survival.
Results showed an increased
survival of 13.6 months for
patients treated with ADT plus docetaxel
than with ADT alone.
Despite improvements in OS and CSS,
survival rates following RT remained lower
than those for elderly
patients who received surgery.
However, in resource - rich environments in Europe and the USA, EVD kills less
than 20 % of
patients infected, suggesting that a better allocation of resources could help boost the
survival rate in Africa.
Patients younger than 65 years, had average progression - free survival times of 11.7 months (combination), 5.5 months (nivolumab) and 2.8 months (ipilimumab), while the 262 patients aged between 65 and 75 had average progression - free survival times of 11.1 months, 12.7 months and 2.9 months respe
Patients younger
than 65 years, had average progression - free
survival times of 11.7 months (combination), 5.5 months (nivolumab) and 2.8 months (ipilimumab), while the 262
patients aged between 65 and 75 had average progression - free survival times of 11.1 months, 12.7 months and 2.9 months respe
patients aged between 65 and 75 had average progression - free
survival times of 11.1 months, 12.7 months and 2.9 months respectively.
We've performed more
than 600 lifesaving lung transplants, and our
patients» one - year
survival rate is No. 1 in the region, exceeding the national average.