Researchers have finally been able to make the charges stick against a long -
suspected tumor suppressor gene.
Not exact matches
One known miR - 182 target is CHEK2, a known
tumor suppressor and
suspected genetic risk factor for high - tension glaucoma.
These rearrangements affected several known and
suspected oncogenes and
tumor suppressor genes, including Notch1, Pten, Ikzf1, Jak1, Phlda1, Trat1, and Agpat9.
They generated a list of
suspected oncogenes and
tumor suppressor genes based on their mutation patterns — and found many more potential cancer drivers than anticipated.
In back - to - back papers published online July 28 in Science, researchers from the Broad Institute, Dana - Farber Cancer Institute, Johns Hopkins Kimmel Cancer Center, the University of Pittsburgh, and the University of Texas MD Anderson Cancer Center have confirmed genetic abnormalities previously
suspected in head and neck cancer, including defects in the
tumor suppressor gene known as p53.