Sentences with phrase «sustained over time by»

After all, dealers and artists alike used to consider premature auction - market debuts a terrifying prospect for emerging talent, because it can either spike their primary market prices to a height that can't be sustained over time by still - immature work, or worse, present an opportunity for an embarrassingly public flop.

Not exact matches

The fact that viable companies are able to sustain their business models by infusing them with readily available capital while they move closer to determining the best course of action for their long - term viability makes it more likely that they will succeed over time.»

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

As we have seen time and again, the flexible workspace market has experienced incredible growth and is sustaining that growth across the world; Savills found that UK serviced office take - up increased by more than 150 % in 2017, while CBRE discovered that the flexible office market has been growing at an average of 13 % per annum over the last decade.

The lesson here is to look for insights by studying an industry deeply over a sustained period of time.

Higher - quality dividend - paying stocks are understood within the industry to mean those issued by large, stable companies that generally invest in profitable projects, manage their expenses effectively, and grow their cash flow — some of the hallmarks of companies that are able to sustain and grow dividends over time.

The countries that have succeeded have done so by running favorable trade balances over a sustained period of time, especially with the United States.

He is the Being who deals with contingency and is capable of decision in time so that order is established over chaos by the action of a will backed by the power necessary to sustain it.

Over a time frame of > 30 y, downward trends in the availability of sugars and sweeteners, reported intake of energy in the form of added sugars and SSBs, and industry data on sugar contributions to SSBs have been paralleled by a sustained rise in the prevalence of obesity and its comorbidities (42).

A bad game by the match officials doesn't gloss over Wenger's and the teams in adequacies in my opinion over a sustained period of time but of course why does that matter when we as fans are told by Ivan we're punching above our weight, the club, our club has so many problems its scary but bad linesman and refs we can't.

The Astros got that first World Series win in Houston by hitting the ball as hard as humanly possible, several times in a row, over a sustained period of time.

I am pessimist by nature and have watched Arsenal for 40 + years — but I see sustained evidence that we have significantly improved our team balance, addressed the gung - ho antics of recent times and upped the work - rate all over the pitch.

The Gunners have a daunting opening Champions League game away at Borussia Dortmund in eight days time, but we have been given a boost by the fact that Marco Reus has sustained an ankle injury in Germany's 2 - 1 win over Scotland last night, and is now likely to miss the match against Arsenal.

In a way I can understand his point of view as he has been left on the sidelines by Wenger many times over the last few years, and has only now got his chance due to the injuries sustained by Mikel Arteta and Matthieu Flamini, and of course Jack Wilshere, who is due to return next month.

Democracy evolved over a period of time and by the time of independence it was in a position to sustain itself.

The investigation into bribery of public officials by the tabloid is focused on «suspected criminality over a sustained period of time» involving tens of thousands of pounds.

«Many people are excited by the potential of using activity trackers to monitor healthy behaviors, but there is very little evidence on who is using them and whether or not use is sustained over time,» said Mitesh Patel, MD, MBA, MS, an assistant professor of Medicine and Health Care Management, and director of Penn Medicine's Nudge Unit.

Previous studies have proven the benefits of vigorous stair climbing over sustained periods of time — up to 70 minutes a week — but scientists set out to determine if sprint interval training (SIT), which involves brief bursts of vigorous exercise separated by short periods of recovery, was an effective and time - efficient alternative for improving cardiorespiratory fitness.

Many climate model simulations focus on the amount of warming caused by emissions sustained over decades or centuries, but the timing of temperature increases caused by particular emission has been largely overlooked.

By contrast, top - down efforts that don't involve close work over sustained periods of time with the communities in question over time are doomed to fail, as the state's own experience shows, Mr. Sciarra argued.

By Frederick Brown Principals create the conditions for effective teaching and learning that is scaled throughout their buildings and sustained over time.

This step - by - step Guide will help communities conceptualize and form a Broad - Based Coalition that will mature over time and ultimately assume primary responsibility for sustaining a system of high - quality pathways.

In examining the issues and exercise of power that are sustained in the long - standing policy of standardized testing in schools, this work provides a big picture perspective on assessment practices over time in the U. S.; by examining the rise of value - added assessment in Tennessee, a fine - grained and contemporary case is provided within that larger context.

The sheer number of variables is evidence that any response by school systems must be multidimensional, targeted at multiple levels of the system, and sustained over time.

Functions The teacher leader: a) Collaborates with colleagues and school administrators to plan professional learning that is team - based, job - embedded, sustained over time, aligned with content standards, and linked to school / district improvement goals; b) Uses information about adult learning to respond to the diverse learning needs of colleagues by identifying, promoting, and facilitating varied and differentiated professional learning; c) Facilitates professional learning among colleagues; d) Identifies and uses appropriate technologies to promote collaborative and differentiated professional learning; e) Works with colleagues to collect, analyze, and disseminate data related to the quality of professional learning and its effect on teaching and student learning; f) Advocates for sufficient preparation, time, and support for colleagues to work in teams to engage in job - embedded professional learning; g) Provides constructive feedback to colleagues to strengthen teaching practice and improve student learning; and h) Uses information about emerging education, economic, and social trends in planning and facilitating professional learning.

Over time, we support our teacher leaders in assuming responsibility for leading and sustaining the collaborative inquiry communities we have established at their sites, with the aim of teacher leaders becoming independent drivers of the work by Year 3 and beyond.

During this session, you will: learn how to get beyond the walls of resistance by debunking the most common myths about change; strengthen your capacity to lead your staff through the change process; apply strategies that will create a school culture in which changes are sustained over time; and understand how to lead change with an unflinching commitment as you make transitions from what is to what can be.

«To achieve such high customer satisfaction scores and sustain them over time is a remarkable feat,» the study concluded, «that remains unmatched by any other e-retailer.»

They ranged from one - time improvisations — such as his black - streaked «Automobile Tire Print,» which he made by having the musician John Cage drive his car over 20 sheets of paper in the street — to a decade of sustained creativity as the resident designer of the Merce Cunningham Dance Company.

Moderated by Sharon Louden, Artist and Editor Panelists include: Sean Mellyn and Jennifer Dalton, Artists and Contributors to «Living and Sustaining a Creative Life» Christian Viveros - Faune, Writer, Curator and Art Critic for the Village Voice Paddy Johnson, is the founding Editor of Art F City and writes a column on art and Internet for artnet news At a time when art is increasingly viewed as a commodity and art - school graduates feel that gallery representation is imperative for making a living and a career, it is more important than ever to show the reality of how an artist sustains a creative practice over time.

Additionally, observational programs are faced with the challenge of sustaining historical time series by sampling with seemingly obsolete instruments in order to maintain comparability over the decades while also utilizing the newest technologies.

It seems hardly any country in the world has moved the decarbonization rate upwards by 1.3 % over a sustained period of time, and the one major economy that may have done so (the UK) has gone through a coal - to - gas transition that can't be repeated, while de-industrializing at the same time.

Our client sustained a number of injuries in the accident, the most serious of which was to his right wrist, described by our orthopedic expert as «chronic and static with a very high likelihood of deteriorating over time.»

Likewise, the extent of injuries sustained by the victim can fade over time.

In fact, these liquidity providers may be crucial to sustaining balanced channels over long periods of time, according to further simulations conducted by Anthony Towns.

«Sustaining the interest will happen through apps, and by proving there really is a value - add over the iPhone,» Parthasarthy told the E-Commerce Times.

While there is a second group threshold outlined by Dunbar as it relates to exclusivity: the «Exclusive» group, with over 150 active members; whereby in order to sustain, the community requires all of our time relegated for social interactions and so is, therefore, singularly consuming.

Required Qualifications * Must be at least 16 years of age * Licensure requirements vary by state * Attention and Focus o The ability to concentrate on a task over a period of time without being distracted * Customer Service Orientation o Actively look for ways to help people, and do so in a friendly manner o Notice and understand customers» reactions, and respond appropriately * Communication Skills o Use and understand verbal and written communication to interact with customers and colleagues o Actively listening by giving full attention to what others are saying, taking time to understand the points being made, asking questions as appropriate, and not interrupting at inappropriate times * Mathematical Reasoning o The ability to use math to solve a problem, such as calculating day's supply of a prescription * Problem Resolution o Is able to judge when something is wrong or is likely to go wrong; recognizing there is a problem o Choosing the best course of action when faced with a complex situation with several available options PHYSICAL DEMANDS: * Remaining upright on the feet, particularly for sustained periods of time * Moving about on foot to accomplish tasks, particularly for moving from one work area to another * Picking, pinching, typing or otherwise working primarily with fingers rather than whole hand or arm * Extending hand (s) and arm (s) in any direction * Bending body downward and forward by bending spine at the waist * Stooping to a considerable degree and requiring full use of the lower extremities and back muscles * Expressing or exchanging ideas by means of spoken word; those activities where detailed or important spoken instructions must be conveyed accurately * Perceiving the nature of sounds at normal speaking levels with or without correction, and having the ability to receive detailed information through oral communication * Visual Acuity: o The worker is required to have close visual acuity to perform activities such as: transcribing, viewing a computer terminal, reading, visual inspection involving small parts * Occasional lifting of up to 30 lbs; exerting up to 30 lbs of force occasionally and / or up to 10 lbs of force frequently, and / or a negligible amount of force constantly to move objects Preferred Qualifications * Previous experience in a pharmacy, retail, medical, or customer service setting * Previous experience as a Pharmacy Technician * PTCB National Certification Education * High School diploma or equivalent (preferred) Business Overview CVS Health, through our unmatched breadth of service offerings, is transforming the delivery of health care services in the U.S..

Using Data in Multi-Agency Collaborations: Guiding Performance to Ensure Accountability and Improve Programs (PDF - 353 KB) Public / Private Ventures & Child Trends (2012) Provides a step - by - step guide to launching a multi-agency data system, making the system work by ensuring partners collect accurate and complete information, analyzing and acting on data to strengthen programming, and sustaining the data collection system over time.

RAV Senior Manager, Business and Service Development, Simon Curran said: «Although most children adjust over time to their parents» separation, however saddened by the experience they have been, exposure to sustained parental conflict is a major risk factor for children's adjustment.

Schools sustain and improve SEL capacity over time by developing Open Circle trainers, coaches and leadership teams, providing training, mentorship, outcome measurement and action planning.

Emerging research from the fields of public health, psychology, education and others demonstrates that the condition of «parent - child connectedness» serves as an important protective factor for a variety of adolescent health outcomes... [Parent - child connectedness] is characterized by the quality of the emotional bond between parent and child and by the degree to which this bond is both mutual and sustained over time.

Schools sustain and improve Open Circle practice over time by developing in - district / in - school trainers and peer coaches, and establishing SEL leadership teams that provide mentorship, outcome measurement and action planning.

Answer: Because much more time, effort and money is expended by newbies in pursuit of quick financial gratification (via the use of learned razzle - dazzle psychological rapport - building techniques) instead of investing in the needed time and effort to build a foundation of knowledge that will sustain them over the long term.