Sentences with phrase «sustained over time in»

Not exact matches

If your ideas can help reduce time - to - collection periods, and if those ideas can be sustained over a long period of time, you'll have a positive impact on NWC, and that, in turn, will enhance the company's value.

Since 1973, the median man working full - time, full - year has seen no sustained growth, dropping from $ 53,291 in 1973 to $ 51,902 in 2002 and falling further over the 2002 - 07 recovery and the recession to $ 50,383 in 2014.

No democracy in the world has been sustained over time without some independent institution that stands up for and advances worker rights, interests and economic welfare.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

«Leveling up your finances — and adding commas — will likely be a result of consistent, positive habits sustained over a long period of time,» says Jason Kirsch, Certified Financial Planner at Marcum Financial Services LLP in Chicago.

In fact, with strong management and sustained execution, we believe it could carry a per - share price higher than $ 133 over time.

Credit concerns typically create a spike in demand for default - free assets such as U.S. government liabilities, so even though there is a much larger float than is likely to be sustained over time without inflation as the ultimate outcome, credit concerns tend to support the value of these liabilities and hence mutes immediate inflation pressures (essentially, monetary velocity declines as these liabilities are sought as a default - free store of value).

He concluded that, based on the current stated amount of underfunding at every big pension fund, if the Dow / SPX declined 10 % or more over a sustained period of time — where «sustained period» is defined as 3 - 4 month — every public pension fund in the country would collapse.

Many of those policies remain in place, sustaining growth and avoiding stagnation until such time as Keynes's animal spirits, which have been crushed over the past seven years, revive.

As we have seen time and again, the flexible workspace market has experienced incredible growth and is sustaining that growth across the world; Savills found that UK serviced office take - up increased by more than 150 % in 2017, while CBRE discovered that the flexible office market has been growing at an average of 13 % per annum over the last decade.

The press release claimed, «For the first time in over a decade, funding needed to sustain the federal government has decreased.

As I noted in Chumps, Champs, and Bamboo, «part of the ability to sustain discipline comes from understanding the profile of returns from that discipline over time.

Higher - quality dividend - paying stocks are understood within the industry to mean those issued by large, stable companies that generally invest in profitable projects, manage their expenses effectively, and grow their cash flow — some of the hallmarks of companies that are able to sustain and grow dividends over time.

well just thinking about these wars in the muslim / mid-east world over religious differences (which may reflect mental states in many ways) in a world where most realize that living in the present moment is best way to happiness and being in the moment in non-strife and awareness through the teachings of masters such as found in the buddhist, taoist, zen, etc., etc., etc. spriritually based practices of religious like thought and teachings, etc. that to ask these scientifically educated populace whom have access to vast amounts of knowledges and understandings on the internet, etc. to believe in past beliefs that perhaps gave basis and inspiration to that which followed — but is not the end all of all times or knowledges — and is thus — non self - sustaining in a belief that does not encompass growth of knowledge and understanding of all truths and being as it is or could be — is to not respect the intelligence and minds and personage of even themselves — not to be disrespected nor disrespectful in any way — only to point out that perhaps too much is asked to put others into the cloak of blind faith and adherance to the past that disregards the realities of the present and the potential of the future... so you try to live in the past — and destroy your present and your future — where is the intelligence in that — and why do people continually fear monger or allow to be fear — mongered into this destructive vision of the future based upon the past?

Some readers will doubtless complain that this conservatism is too Romantic, too English, one that can not be sustained over the course of a life, and certainly not in times of crisis or moral and social decay.

A living organism is a developing system sustained through multiple interactions over periods of time with other systems in the environment, giving interchanges of energy.

Despite his «reformed subjectivist principle,» Whitehead does not, in my opinion, adequately address such high level human experiences as responsibility and our sense of a sustained «being - here» over time.

He is the Being who deals with contingency and is capable of decision in time so that order is established over chaos by the action of a will backed by the power necessary to sustain it.

Food is not fixed in time, yet we have been poor managers of our resources over the years as human civilization has progressed and today stand at a situation where sustaining our biggest source of energy has transformed into our biggest problem coupled with environmental degradation.

The result is that the caffeine is released in your body over a longer period of time, compared to the quick jolt from coffee, giving you sustained energy and mental clarity.

There remains a need for future research to particularly show the effects of sustained or longer - term exposures to food advertising and to test whether the observed increases in intake after acute exposures are not later compensated for and, therefore, could lead to weight gain over time (54).

It will set you up in the morning with a tasty savoury flavour and get your body burning fat and protein over a sustained period of time rather than an insulin - spiking quick release carbohydrate or sugary breakfast likely to have you starving for lunch... or even worse, craving sugary things at 11 am!

Over a time frame of > 30 y, downward trends in the availability of sugars and sweeteners, reported intake of energy in the form of added sugars and SSBs, and industry data on sugar contributions to SSBs have been paralleled by a sustained rise in the prevalence of obesity and its comorbidities (42).

A bad game by the match officials doesn't gloss over Wenger's and the teams in adequacies in my opinion over a sustained period of time but of course why does that matter when we as fans are told by Ivan we're punching above our weight, the club, our club has so many problems its scary but bad linesman and refs we can't.

According to The Sun, the 24 - year - old is «in a race against time to be fit» having sustained a hamstring injury last weekend in the win over Liverpool, and so Tottenham will have to carefully monitor him in the next 24 hours to determine whether or not he can feature against the Red Devils at Old Trafford.

The Astros got that first World Series win in Houston by hitting the ball as hard as humanly possible, several times in a row, over a sustained period of time.

The Gunners have a daunting opening Champions League game away at Borussia Dortmund in eight days time, but we have been given a boost by the fact that Marco Reus has sustained an ankle injury in Germany's 2 - 1 win over Scotland last night, and is now likely to miss the match against Arsenal.

In a way I can understand his point of view as he has been left on the sidelines by Wenger many times over the last few years, and has only now got his chance due to the injuries sustained by Mikel Arteta and Matthieu Flamini, and of course Jack Wilshere, who is due to return next month.

Financial Fair Play (FFP) regulations were introduced in 2012 to «reduce the levels of losses being incurred at some clubs and, over time, establish a league of financially self - sustaining professional football clubs».

«Gylfi Sigurdsson will see a specialist this evening to determine a time frame for recovery from the knee injury he sustained in Saturday's Premier League win over Brighton at Goodison Park,» Everton's statement said.

In the newest generation of parents there are increasing numbers of higher earning mothers, and fathers willing to take on more of the care of children; in many couples both partners work full - time — but the childcare costs which hamper the poorest in entering the workforce also lead to difficulties for parents sustaining employment over timIn the newest generation of parents there are increasing numbers of higher earning mothers, and fathers willing to take on more of the care of children; in many couples both partners work full - time — but the childcare costs which hamper the poorest in entering the workforce also lead to difficulties for parents sustaining employment over timin many couples both partners work full - time — but the childcare costs which hamper the poorest in entering the workforce also lead to difficulties for parents sustaining employment over timin entering the workforce also lead to difficulties for parents sustaining employment over time.

Finding a way to reconcile two competing demands - minimizing contact in practice in order to reduce the number of concussions sustained and the number of hits players sustain over the course of a week and a season that emerging science, now more than ever, suggests may have a deleterious cumulative effect [26] on a player's cognitive function over the long term, while at the same time maximizing the amount of time in practice learning how to tackle and block without head - to - head contact - time that is needed to maximize the protective effect of proper tackling on the number of head - to - head hits players sustain in game action, which can not only result in concussion, but catastrophic neck and spine injuries - is challenging, but clearly not impossible.

It's adjustable in size, using high quality Velcro, to sustain a perfect fit over time as a nursing mother's size changes.

«Having the common experience of open adoption was key in the beginning, but we also have similar values and parenting styles,» which she says helped sustain the friendships over time.

The patented design is adjustable in size, using high quality Velcro, to sustain a perfect fit over time as a nursing mother's size changes.

Democracy evolved over a period of time and by the time of independence it was in a position to sustain itself.

Despite a sense of inevitability, he believes with a sustained effort he can win over sceptics in Parliament when expansion is voted on in 14 months» time.

Investment in north England will require sustained attention over a long period of time, not just one short announcement.

I hope those Fabian members and other Next Left readers who are not already part of the Avaaz network will look at getting involved in this campaign and the other initiatives and campaigns: the case for sustained and positive civic pressure over time is massively important in between the big summits which hit the headlines.

A comprehensive evaluation of the cleanyourhands campaign has shown that this important intervention has produced sustained improvements in hand hygiene over time.

«However, this strategy becomes more challenging to sustain over a long period of time because it involves increasingly difficult choices in areas that are subject to repeated cuts.

Preston thinks one of the biggest challenges in developing a new communication effort across an institution is crafting messages «that are representative of the diversity of the staff and their research,» and sustaining coordinated communication efforts over time.

Viral social campaigns can effectively capture the attention and support of mass audiences, but in order to make viral altruism stick, more gradual and deeper engagement with a social cause is required over a sustained period of time.

«Our results suggest that both the clinical effectiveness and the impressive effects on the quality of life under biological treatment as used in clinical practice are sustained over time.

Current sage - grouse conservation plans focus on protecting selected «priority areas,» but these areas vary in size and proximity to each other — will they be able to sustain thriving, interconnected populations over time?

Weak muscle contractions, sustained over a long period of time — as in during a bike ride — change proteins, mainly ones involved in metabolism.

In some cases, at risk populations live in environments that are remote and as a result it is expensive to collect data over a sustained period of timIn some cases, at risk populations live in environments that are remote and as a result it is expensive to collect data over a sustained period of timin environments that are remote and as a result it is expensive to collect data over a sustained period of time.

School - based prevention programs were found to be successful in having a significant impact on dating violence knowledge and attitudes and, unlike victimization experiences, changes in knowledge were sustained over time.

«It is challenging to lose weight, but if women commit to losing 10 percent of their body weight and sustain that over time, it can have a large impact on overall risk factors associated with heart disease and diabetes,» said Cynthia A. Thomson, Ph.D., R.D., co-author and Professor in the Mel and Enid Zuckerman College of Public Health and Director of the University of Arizona Canyon Ranch Center for Prevention & Health Promotion in Tucson.

«A sustained increased heart rate of over 100 beats per minute could mean there is not enough time for the heart to fill properly, leading to a fall in the volume of blood being pumped,» says Ann Robinson, a London - based general - practice doctor.