What we were surprised to find out was that the real differences we could detect in terms
of when we did the
swap experiments to say which yeast could outperform the other — what we learned was that the GAL1 gene, that the part [
of] that, the DNA sequence is outside
of the GAL1 gene, it acts as a switch to turn up or turn down GAL1 expression, that had evolved considerably from the ancestral
situation; and same for the GAL3.And then what had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort
of a loosely regulated
kind of available anytime sensor
of galactose and GAL1 had evolved to be an incredibly tightly regulated, in fact, it's the most tightly regulated gene you know
of in yeast.
Harry says their team decided to
swap Cocos2D for Unity in the midst
of the game development process to achieve the desired level
of visual complexity — and that's exactly the
kind of situation you might find yourself in.