As a result, cell division occurred at the position of the nucleus, leading to nearly
symmetric cell division, where the generated cells were similar in size.»
Although unequal division occurs among stem cells — allowing one daughter cell to remain a stem cell while the other matures into another cell type, such as a skin or muscle cell — the goal of a normal
symmetric cell division is to generate identical daughter cells and increase cell number.
Not exact matches
One of the biggest puzzles in developmental biology is how a
symmetric ball of
cells ends up with left and right sides that differ.
In parallel, the roles of
symmetric and asymmetric
cell divisions are investigated as a mechanism for governing stem
cell self - renewal and differentiation during embryonic development and in the adult.
ASPM regulates
symmetric stem
cell division by tuning Cyclin E ubiquitination.
Stem
cell replacement is thought to be driven by
symmetric division of existing stem
cells; however, alternate mechanisms to
symmetric divisions are largely unexplored.
No significant differences were seen between the normoxic and hypoxic anoikis - resistant populations collected from MCF7
cells and a single significant gene change (PIP) was seen in T47D (Table 1) suggesting that the CSC - enriched population remains virtually unchanged following hypoxic culture and the increase in MFC, HFC, and tumor initiating
cells is, therefore, due to expansion of the population, perhaps by increased
symmetric self - renewal of the CSC or de-differentiation of early progenitor
cells, rather than simply the acquisition of anoikis resistance in non-CSC.
The first talk of the meeting was by Juergen Knoblich, and it was great to hear about his current projects, using Drosophila genetics to understand
cell cycle exit and quiescence plus the contribution of changing the balance of asymmetric versus
symmetric divisions in development of various disorders.
SDMA,
symmetric dimethylarginine, is produced in every
cell and released into the body's circulation during protein degradation.