This finding implies that the tip of a growing
sympathetic nerve fiber elongates along a diffusion gradient of NGF released by the target organ.
Not exact matches
Immature
sympathetic neurons respond to NGF with a burst of metabolic activity that provides the material necessary for the growth of the
nerve fiber and the manufacture of molecules of neurotransmitter.
The addition of a small amount of venom to the culture medium in the absence of the extract of sarcoma 180 elicited the growth of the same dense halo of
nerve fibers around an isolated sensory or
sympathetic ganglion.
Rather it seemed the tumor was releasing some chemical factor that was in turn inducing the remarkable growth of the
sympathetic ganglia and the exuberant branching of their
nerve fibers.
In addition to apparently being essential to the survival of immature
sympathetic neurons NGF seems to play a vital role in guiding
nerve fibers toward their corresponding target organs.
Apparently the NGF injected into the brain diffused through the motor and sensory roots of the spinal cord and reached the
sympathetic chain ganglia flanking the cord, where it induced the outgrowth of
nerve fibers.
Studies conducted by Hendry at the Australian National University and by K. Stockel and H. Thoenen at the Basel Institute for Immunology have demonstrated that NGF is taken up at the terminal
nerve endings of the
sympathetic fibers and transported back to the neuronal cell body along the axon.
He wanted to see how sensory and
sympathetic ganglia, sending out their
nerve fibers to these peripheral «fields of innervation,» would adjust to the different dimensions and configurations of the foreign organs.
It is important to understand that your ANS is divided into two distinctly separate nervous systems, one which stimulates the
nerve fibers, the
sympathetic nervous system or SNS, and the other which sedates
nerve fibers, the parasympathetic nervous system or PNS.
Perhaps the
sympathetic activation with water drinking involves osmoreceptive or sodium - sensitive afferent
nerve fibers (21, 22).