Sentences with phrase «synapse formation in»

The following position is available at the Department Experimental Immunology of the Helmholtz Centre for Infection Research (HZI) in Braunschweig: PhD candidate: Control of immunological synapse formation in regulatory T cells.

In one study conducted at the New York School of Medicine, researchers were able to observe synapse formation in the brains of genetically engineered mice.

Title: Selective synapse formation in the retina

«Visualization of newly formed synapses with unprecedented resolution: Researchers optimized a spatiotemporally controlled method to induce, visualize synapse formation in cortical neurons.»

«New theory of synapse formation in the brain.»

Not exact matches

And those mushy, sentimental notions find their articulation in the infants» brains in precise neurochemical reactions: the formation of a synapse, the pruning of a dendrite, the methylation of a DNA sequence.

«Aberrant synapse formation is important in the pathogenesis of schizophrenia and autism,» says Osaka University Professor Toshihide Yamashita, one of the authors of the study.

The genes we detect are involved in the regulation of cell development, and are specifically important in synapse formation, axon guidance and neuronal differentiation.

Eroglu's earlier work has shown that thrombospondins are released by brain cells called astrocytes and boost new synapse formation between neurons in the brain.

MHCI limits synapse density by inhibiting insulin receptors, which regulate the body's sugar metabolism and, in the brain, promote synapse formation.

However, studying the general mechanisms of synapse formation and distribution in dendrites has been challenging due to a lack of reliable methods that trigger and monitor synapse formation.

A new study just published in the journal Glia and available online on July 11th, details the newly discovered mechanism by which astrocytes are involved in inhibitory synapse formation and presents strong evidence that Transforming Growth Factor Beta 1 (TGF β1), a protein produced by many cell types (including astrocytes) is a key player in this process.

In the hippocampus, a major component responsible for memory, neural activity, synapse formation and expression of brain - derived neurotrophic factor (BDNF) were reduced in these mice (Image 2In the hippocampus, a major component responsible for memory, neural activity, synapse formation and expression of brain - derived neurotrophic factor (BDNF) were reduced in these mice (Image 2in these mice (Image 2).

It interferes with the production of a protein critical to synapse formation during a brief period in early development when the brain is optimizing its ability to process sensory input.

In summary, our results demonstrate that PKN1 functions as a developmentally active gatekeeper of AKT activity, thereby fine - tuning axonal outgrowth and presynaptic differentiation of Cgcs and subsequently the correct PF - PC synapse formation.

Dr. Parsons has shown that while there is some degree of tonic endocannabinoid formation in the brain, an overt influence of endocannabinoid signaling requires synapse - specific activation of endocannabinoid formation.

In other words, it would take 10 million times as much BDNF to get as much new synapse formation as Dihexa.

Differential roles for Wiskott - Aldrich syndrome protein in immune synapse formation and IL - 2 production.

The hypothesis is that astrocytes play a crucial role in dictating synapse formation and function via the release of specific proteins that determine the type of synapse that will form, and the strength of that synapse.

Temporal changes in synaptic proteins in hippocampal slices indicated acute synaptic loss, followed by synapse formation and maintenance phases.

For example, our discovery of HORMAD1 (Fig 2) and HORMAD2, two proteins that preferentially associate with unpaired / unsynapsed meiotic chromosome cores / axes, allowed us to address how progression in meiosis is coordinated with crossover formation, and how meiotic checkpoints / quality control ensure that only those meiocytes progress in meiosis that correctly paired and synapsed their homologous chromosomes.

TKF: You then applied schizophrenia drugs to these not - fully - mature cultured neurons derived from schizophrenic patients and found that some of these drugs reversed the abnormalities in synapse formation you saw.