Sentences with phrase «synapse number»

In a series of electrophysiological studies, Zoghbi's team further found that neurons from animals with depleted MECP2 levels have reduced electrical activity due to a smaller number of excitatory synapses, whereas cells from animals carrying an extra copy of the gene have increased electrical activity because of an increase in synapse number.

Approaches such as electrophysiology to assess synaptic strength and plasticity, immunohistochemistry to assess synapse number, and behavioral assays to assess learning

Identification and characterization of astrocyte - secreted signals that regulate neuronal synapse number and strength during development

«MHCI levels are altered in the Alzheimer's brain, and altering MHCI levels in mice disrupts memory, reduces synapse number and causes neuronal insulin resistance, all of which are core features of Alzheimer's disease,» Boulanger said.

«Gene links risk of psychiatric disease to reduced synapse numbers.»

Not exact matches

Now, a «Clean Energy for New York» report commissioned by Riverkeeper and the Natural Resources Defense Council from Synapse Energy Economics shows the power can be replaced with a combination of resources and upgrades in a number of scenarios.

Functionally, docking sites limit the maximum number of vesicles that can be released at each action potential, this determines the strength of the synapse.

Remarkably, giving animals injections of lithium salts — which mimics WNT signaling by inhibiting the molecule GSK3 — or giving animals a more specific GSK inhibitor, the researchers were able to restore normal synapse and spine numbers and also improve some of the most significant psychiatric - like behavioral abnormalities in these mice.

Loss of synapses and synapse function sit at the heart of a number of diseases, not just neurodegenerative examples such as dementia and Parkinson's disease but also conditions such as diabetes.

«It is a sort of shepherding effect by alpha - synuclein that occurs away from the synapse itself, and controls the number of synaptic vesicles used in each transmission,» Fusco said.

Future therapies will have to be based on strategies that act by reducing or increasing the number or activity of specific subtypes of pre - and postsynaptic receptors, transporters, and ion channels, or other membrane molecules at the synapse, and by strategies that exploit the new possibilities offered by stem cell technology and targeted repair.

It has come to our attention that a small number of people are having trouble when attempting to launch the PS3 version of Frozen Synapse Prime, specifically when trying to progress past the «Change Screen Space» section of the initial launch process.

Sales for a number of our digital games on PC, including the PJ Series, Cloud Chamber and Frozen Synapse Prime.

I'm a big PC gamer, at the moment I've been playing Jagged Alliance 2 and Frozen Synapse after work as well as my other games on Steam, I think they number around 400 at the moment!

Given this, Synapse and SEA modeled a number of other scenarios in which the Massachusetts RPS is adjusted to increase by 2 percent per year, rather than 1 percent per year, as it does today.

Sarah Jackson, an analyst with Synapse Energy Economics Inc. in Cambridge, Mass., said the company's cash flow numbers show that consumers will lose «a great deal of money» in the next few years through the proposed PSR and will not «make that money back up» for at least the next 10 years.

Synapse is thrilled to announce the release of a new report, Show Me the Numbers: A Framework for Balanced Distributed Solar Policies.

No longer limited by onboard device memory, Razer Synapse 2.0 brings the brain of your Razer hardware to the cloud allowing you an infinite number of profiles, configurations, and allows for longer, more complex macros.