With this noninvasive method, researchers may be able to follow the progression of many brain disorders, including epilepsy and Alzheimer's disease, by measuring changes
in synaptic density over time.
«This opens the door to follow the natural evolution
of synaptic density with normal aging and follow how drugs can alter synapses or synapse formation.»
Scientists have proven that magnesium is important to the central nervous system and
promotes synaptic density and plasticity — which are essential for optimal learning and memory.
Both
hippocampal synaptic density and LTP as well as contextual fear conditioning and spatial learning vary as a function of maternal care in the rat [10], [15].
Mice genetically engineered to lack PirB, or treated with an infusion of soluble PirB directly into the brain, also showed an increase
in synaptic density and signalling in the visual cortex.
For their study, the research team set out to develop a method for measuring the number of synapses, or
synaptic density, in the living brain.