Sentences with phrase «synaptic terminals»

Synaptic terminals are like the tiny buttons at the end of nerve cells that help transmit messages in our brain. Full definition
CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration.
With two - photon microscopy and other techniques, he studies in detail how synaptic terminals change — creating memories and learning — when stimulated.
An intriguing new study of their subcellular structure could help explain how bipolar synaptic terminals meet such excessive energy demands.
However, it has also been proposed that 4 - AP might lead to clinical improvement by an increase in neurotransmitter release or an increase in the number of activated synaptic terminals [47].
Unexpectedly, the team discovered a thick band of microtubules, a component of the cell's cytoskeleton, that extended from the axon of the neuron into the synaptic terminal and then looped around the interior periphery of the terminal.
The microtubule band appeared to associate with mitochondria — organelles known for providing energy to cells — in the synaptic terminal.
The findings suggest that these previously unknown microtubule structures provide a «roadway» for the transport of mitochondria crucial to maintain energy supplies into the synaptic terminals of these highly active neurons associated with vision.
When the researchers administered drugs to inhibit the movement of certain «motor» proteins that transport mitochondria and other cargo within the cell by traveling along microtubules, the mitochondria accumulated in the axon of the neuron and never made it to the synaptic terminal.
It starts when an electrical signal, the action potential, reaches the synaptic terminal of the presynaptic neuron.
This «action potential» propagates down the long axon (right, below) and triggers the release of chemical messengers stored at the synaptic terminals — where neurons talk to each other.
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