Sentences with phrase «synaptic vesicles at»
The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD - 2 / liprin and UNC - 10 / RIM - dependent interactions.
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Beginning in 1988 Scheller, then at Stanford, succeeded in characterizing several key proteins necessary for synaptic vesicle fusion with the presynaptic membrane, the prerequisite step for neurotransmitter release.
To determine whether the protein in question, at the time known as BNPI, mediated the transport of glutamate into synaptic vesicles, the researchers inserted the BNPI DNA into rat cells that normally lacked BNPI protein.
In the late 1990s, he and Reinhard Jahn, now at the Max Planck Institute of Biophysical Chemistry, determined the structures of some of the key proteins and complexes involved in the process of synaptic vesicle fusion.