«It is a sort of shepherding effect by alpha - synuclein that occurs away from the synapse itself, and controls the number of
synaptic vesicles used in each transmission,» Fusco said.
Not exact matches
We generated knockout mice lacking synaptobrevin / VAMP 2, the vesicular SNARE protein responsible for
synaptic vesicle fusion in forebrain synapses, to make
use of the exquisite temporal resolution of electrophysiology in measuring fusion.
Thomas Südhof
used powerful biochemical and molecular biological approaches to identify other important
synaptic vesicle proteins.
Richard Scheller has
used a combination of biochemistry, molecular biology, and cell biology to identify several key
synaptic vesicle and plasma membrane proteins involved in fusion of the neurotransmitter - containing
vesicles with the membrane of the presynaptic terminal.