Elizabeth Sheldon: Morphological analysis
of synaptogenesis after compensatory regeneration in the audiotry system of the cricket Gryllus bimaculatus (Advisor: H. Horch)
Interestingly, the chromosomal region containing the protocadherin - α, - β, and - γ (Pcdh) gene families implicated
in synaptogenesis show the highest differential response to maternal care.
During his PhD work at the Lyon Neuroscience Center (France), he worked on the regulation of
postnatal synaptogenesis and synaptic remodeling associated with learning and memory.
Eroglu C, Allen NJ, Susman MW, O'Rourke NA, Park CY, Ozkan E, Chakraborty C, Mulinyawe SB, Annis DS, Huberman AD, Green EM, Lawler J, Dolmetsch R, Garcia KC, Smith SJ, Luo ZD, Rosenthal A, Mosher DF, Barres BA (2009) Gabapentin receptor alpha2delta - 1 is a neuronal thrombospondin receptor responsible for excitatory
CNS synaptogenesis.
And there are a number of ways you can
support synaptogenesis and promote the formation of new brain synapses.
It's interesting to note that quercetin increases the absorption of resveratrol, so it's a good idea to take them both together if you want to
increase synaptogenesis and form new brain synapses (47).
The good news is that researchers now know that
synaptogenesis occurs in the brain throughout our entire lives (7 - 8).
Researchers have found that increasing magnesium levels in the brain improves learning and memory by
promoting synaptogenesis (28 - 29).
Caffeinated coffee increased plasma levels of granulocyte - colony stimulating factor (GCSF), which seemed to improve the cognitive performance of AD transgenic mice with the recruitment of bone marrow cells,
enhanced synaptogenesis, and increased neurogenesis.
By combining the transcriptomic analysis to a functional approach, we have revealed a yet unknown neuropathological mechanism of DM1 that links gene defects in cells of the neural lineage to dysfunction in neuritic outgrowth and
synaptogenesis.
Homer 1, an actin binding protein that is induced by BDNF [72], belongs to a family of scaffolding proteins that localize at the postsynaptic density (PSD)[73, 74] and is believed to play a critical role in signal transduction,
synaptogenesis and receptor trafficking at synapses [75].
Synaptogenesis and development of pyramidal neuron dendritic norphology in the chimpanzee neocortex resembles humans.
«I don't think we know enough yet to say that nutrients in themselves support neurogenesis (the growth of neurons) and
synaptogenesis (the growth of neural connections),» Greenwood said.