Sentences with word «synaptophysin»
Complementary DNA and genomic clones were isolated and sequenced corresponding to rat and human synaptophysin (p38), a major integral membrane protein of synaptic vesicles.
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The structure of synaptophysin suggests that the protein may function as a channel in the synaptic vesicle membrane, with the carboxyl terminus serving as a binding site for cellular factors.
The rise in C3 protein level correlated with decreases in synaptic puncta and synaptophysin densities and synaptic protein, neuron loss, and reduced synaptic plasticity.
In addition, potentiation is accompanied by a rapid and long - lasting increase in the number of clusters of the presynaptic protein synaptophysin and the number of sites at which synaptophysin and GluR1 are colocalized.
The analysis also showed reduced production of two proteins important for neuron - to - neuron communication at synapses: synaptophysin and a glutamate receptor protein.
Synaptophysin in (f) by immunoblot by in brain homogenates; for regional effects on synaptophysin and MAP2, analyzed in serial sections by immunohistochemistry, see Fig. 8 in [22]-RRB-.
mThy1 - AS mice administered only control IgG1 suffered dendritic atrophy (as suggested by reduced staining with MAP2) and synaptic loss (evaluated with postsynaptic density - 95 (PSD - 95) and synaptophysin) across several regions of the brain, but this neurodegenerative damage was substantially prevented in mice administered 1H7, 5C1, or 9E4.
Aged mutant amyloid precursor protein mice with established disease showed a near complete restoration in levels of synaptic and neuronal proteins after exposure to young blood in parabiosis (synaptophysin P =.02; calbindin P =.02) or following intravenous plasma administration (synaptophysin P <.001; calbindin P =.14).
No significant changes in DCX, NeuN, synaptotagmin, and synaptophysin were detected.
Ginger significantly increased nerve growth factor (NGF), which stimulates the growth of new neurons, and synaptophysin and PSD - 95, two indicators of higher synapse formation.