Sentences with phrase «synovial sarcoma»
Synovial sarcoma is a type of cancer that affects soft tissues, such as muscles and tendons in the body. It is a rare and aggressive cancer that can occur in any part of the body, but it most commonly affects the limbs, particularly in young adults. Full definition
These data compare favorably to mOS for approved second line and later sarcoma agents, which is only 12.4 - 13.5 months, as well as a published mOS of 11.7 months for synovial sarcoma patients specifically; the largest patient population enrolled in this trial.
immunedesign.com
Capecchi recently used this approach to solve a biological mystery about a rare, aggressive childhood cancer called synovial sarcoma.
In the U.S., the pair are conducting several phase 1/2 studies for the med in patients with synovial sarcoma, multiple myeloma, melanoma, NSCLC and ovarian cancer.
A case of primary pharynx synovial sarcoma was reported in this paper.
Having started with many sets of mice, Capecchi narrowed the search to a single set that now serves as an animal model of synovial sarcoma.
The randomized, open label Phase 2 trial is ongoing and evaluating CMB305 and atezolizumab in patients with locally advanced, relapsed, or metastatic synovial sarcoma or myxoid / round - cell liposarcoma, two types of sarcoma that tend to express NY - ESO - 1 broadly.
Finding the right clinical trial for Synovial sarcoma can be challenging.
Synovial sarcoma is a relatively common periarticular soft tissue malignancy, occurring mostly in the extremities of younger patients.
The terms «Synovial sarcoma» returned 295 free, full - text research articles on human participants.
A total of 48 patients were included in the analysis, across six cohorts: liposarcoma (6 patients), vascular sarcomas including angiosarcoma and leiomyosarcoma (10 patients), undifferentiated pleomorphic sarcoma (5 patients), synovial sarcomas (5 patients), osteosarcomas (5 patients), and other sarcoma subtypes (17 patients).
Synovial sarcoma is a rare soft tissue sarcoma characterized by a t (X; 18) translocation, which results in a SYT - SSX gene fusion.
Following organizations serve the condition «Synovial sarcoma» for support, advocacy or research.
Synovial sarcoma (SS) is a rare tumor.
The terms «Synovial sarcoma» returned 33 free, full - text review articles on human participants.
Synovial sarcoma is a cancer in the joints with a five - year and ten - year survival for people with Grade 3 tumors or metastatic disease of less than 25 % and 15 %, respectively, and Myxoid round cell liposarcoma is a malignant tumor that most often occurs in the deep - seated soft tissues of the extremities.
Soft Tissue Sarcoma Opportunity: in both our monotherapy single arm Phase 1 and combination randomized Phase 2 studies, we are focusing on two types of sarcoma where we believe there is significant unmet need: synovial sarcoma and Myxoid round cell liposarcoma.
Status: CMB305 is currently in several stages of clinical development, including a monotherapy Phase 1 trial and a fully - enrolled randomized Phase 2 trial, primarilyin patients with two subtypes of soft tissue sarcoma (synovial sarcoma or myxoid / round - cell liposarcoma).