Sentences with phrase «synthase which»

AgmaMAX ® -(Agmatine Sulfate)- a metabolite of arginine that plays a role in the production of nitric oxide by the modulation of nitric oxide synthase which are enzymes that play a role in nitric oxide production *.

Not exact matches

Through a lot of boring sciencey steps, our body produces something called nitric oxide synthase (NOS) which may cause blood vessels to expand, reducing blood pressure.

ZmPSY1 — phytoene synthase from another food crop, maize, which catalyzes the condensations of two molecules of geranylgeranyl diphosphate to form 11 - cis - phytoene, the first committed step in the carotenoid biosynthetic pathway;

The genetically modified organism (GMO) is wheat Triticum aestivum, which has been transformed with one or both of the following synthetic genes: (E)- β - farnesene synthase and farnesyl diphosphate synthase.

The researchers then modeled a new system with the same process: the mitochondrial enzyme ATP synthase, which also exhibits a distinct conformational change that is dictated by the application of force to the enzyme structure, which is propagated via tensegrity.

They used cryo - EM analysis to decipher the engineered ATP synthase, which was synthesized in yeast and reconstituted into nanodiscs to allow for structural analysis.

The study, published by the journal Science via First Release on April 12, paves the way for determining the structures of other functional states of the ATP synthase, which has been the subject of structural studies for decades in labs across the globe.

Neufeld's group recently found that the enzyme nitric oxide synthase 2 (NOS - 2), which produces toxic levels of the gas nitric oxide, is active in the eyes of rats that have their eyes» drainage channels blocked, causing an artificial form of glaucoma.

The study, which appears online October 29 in the journal Science Signaling, describes a previously uncharacterized interaction between GRK2 and an enzyme called endothelial nitric oxide synthase (eNOS), in which the two enzymes attempt to block one another's activity, with different outcomes on heart function.

FASN encodes the enzyme fatty acid synthase, which is responsible for making fatty acids — an essential source of energy.

The team is already performing additional studies on the molecules that are altered by J147's effect on the mitochondrial ATP synthase - which could themselves be new drug targets.

The key to controlling which route isocitrate will take seems to lie in the enzymes surrounding all these reactions: the enzyme isocitrate dehydrogenase keeps it for the fat - metabolism and energy production cycle; the enzymes isocitrate lyase and malate synthase divert it away into biosynthetic processes in the bacterium.

They first introduced three genes from a soil bacterium called Saccharopolyspora erythraea, which together produce an enzyme called a polyketide synthase, which produces one particular polyketide.

The team eliminated three of the four known starch synthases by inserting backward copies of the genes for each one into the potato genome, which, through an unknown mechanism, interferes with the translation of the nearby normal gene.

Despite the substantial differences between these two classes of natural products, each is synthesized biologically under the control of exceptionally large, multifunctional proteins termed polyketide synthases (PKSs) and non-ribosomal peptide synthetases (NRPSs) that contain repeated, coordinated groups of active sites called modules, in which each module is responsible for catalysis of one complete cycle of polyketide or polypeptide chain elongation and associated functional group modifications.

Russell has since embellished his theory, adding that a mineral called green rust, which can form in vent chimneys, can exploit the flow of protons at a vent in much the same way as ATP synthase.

On the research applications front, Dr. Chia Tet Fatt, a young scientist from the Natural Sciences Academic Group at the National Institute of Education, revealed Singapore's very first genetically modified organism (GMO)-- a transgenic resveratrol producing red lettuce for the prevention of cancer and cardiovascular diseases — which was developed by introducing the stilbene synthase gene into a red plant and diverting the precursors into resveratrol synthesis.

Focus of this project is the CaaX processing microcompartment transiently formed at the ER, which is required for the modification of yeast Chs4, a regulatory subunit of the chitin synthase (CHS) III complex.

Two of these SNPs are within a single gene, which codes for the enzyme nitric oxide synthase 2 (NOS2).

The team is already performing additional studies on the molecules that are altered by J147's effect on the mitochondrial ATP synthase — which could themselves be new drug targets.

You should read about the enzyme ATP synthase, which has a similar structure to the motor driving a flagellum.

Nitric oxide (NO) is endogenously synthesized by nitric oxide synthases (NOSs) which convert L - arginine to L - citrulline and NO in the presence of oxygen and several cofactors.

Mitochondrial membrane ATP synthase (F (1) F (0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.

The most abundant resistance gene was sul2, which encodes for a sulfonamide resistance variant of dihydropteroate synthase — an enzyme essential for folate synthesis [25].

Despite this, we were able to pinpoint two RNA pseudouridine synthases, which were each strongly linked to a separate set of loci across the chromosome, representing biologically plausible targets of co-selection.

The protein chosen for this study was the enzyme 3 - deoxy - D - manno - octulosonate 8 - phosphate synthase (KDO8PS), which is a potential antibiotic target.

We have the fructose mechanism that will increase or decrease the endothelial synthase enzyme which will decrease the vasodilation, i.e. cause constriction of the blood vessels, and we also have plasminogen activator inhibitor mechanism.

Recent studies demonstrate that NO - synthase participates in the regulation of protein and energy metabolism in skeletal muscle by fine - tuning and stabilizing complex signaling systems which regulate protein synthesis and degradation.

Even more encouraging is evidence that polyphenols in olive oil can interact with a hereditary gene variant of endothelial nitric oxide synthase (the NOS3 Glu298Asp polymorphism, which is a risk factor for hypertension and coronary artery disease), to improve endothelial function after meals.19 So, even if genetics are not in your favor, olive oil may help.»

Studies show that human cancer cells express high levels of the fatty acid synthase enzyme, which is associated with aggressive tumor behavior and tumor - cell growth.

Second, curcumin helps stimulate a very important genetic pathway known as the NRF2 pathway, which activates a whole set of antioxidant genes, including genes like glutathione synthase (which is the body's natural way of making glutathione) and glutathione peroxidase (which is the way the body uses glutathione to fight off damage) and is just one way that curcumin fights damaging oxidants.

Even though oral arginine can be completely ineffective in small doses, if the dosages are too high (depending on the individual recipient) arginine can actually disrupt endothelial nitric oxide synthase (eNOS) levels by activating a feedback mechanism which the body utilizes to mitigate excessive formation of nitric oxide (NO).

Lipolysis, the release of stored fat, was increased; lipogenic enzymes, including fatty acid synthase, were reduced; and uncoupling protein was increased in brown fat, which results in burning more fat for heat production.How much weight loss was experienced by the leucine - deprived mice, and how did it occur?