Sentences with phrase «synthases from»

This study also presents the structure - based mechanisms for substrate specificities of various PHA synthases from different classes.

ZmPSY1 — phytoene synthase from another food crop, maize, which catalyzes the condensations of two molecules of geranylgeranyl diphosphate to form 11 - cis - phytoene, the first committed step in the carotenoid biosynthetic pathway;

In two papers published back - to - back in Biotechnology Journal online on November 30, 2016, a Korean research team led by Professor Kyung - Jin Kim at Kyungpook National University and Distinguished Professor Sang Yup Lee at the Korea Advanced Institute of Science and Technology (KAIST) described the crystal structure of PHA synthase from Ralstonia eutropha, the best studied bacterium for PHA production, and reported the structural basis for the detailed molecular mechanisms of PHA biosynthesis.

Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.

Not exact matches

One, called phytoene synthase, had been taken from daffodils.

ATPIF1 interacts with ATP synthase to shut it down and prevent it from consuming the mitochondrion's dwindling ATP supply but, in the process, also worsens the mitochondrion's membrane potential

But polyketide synthases don't work without a co-factor called phosphopantetheine, so the researchers also introduced a gene from the soil bacterium Bacillus subtilis that encodes the enzyme that attaches phosphopantetheine to the polyketide synthase.

But when they cross back the other way, an enzyme called ATP synthase steals energy from the flow and stores it in molecules of ATP.

They first introduced three genes from a soil bacterium called Saccharopolyspora erythraea, which together produce an enzyme called a polyketide synthase, which produces one particular polyketide.

Our cells produce hydrogen sulfide from the amino acid L - cysteine, thanks to help from two enzymes, cystathionine β - synthase (CBS) and cystathionine & # 947 - lyase (CSE).

On the research applications front, Dr. Chia Tet Fatt, a young scientist from the Natural Sciences Academic Group at the National Institute of Education, revealed Singapore's very first genetically modified organism (GMO)-- a transgenic resveratrol producing red lettuce for the prevention of cancer and cardiovascular diseases — which was developed by introducing the stilbene synthase gene into a red plant and diverting the precursors into resveratrol synthesis.

The expression of mRNA for factors involved in promoting mitochondrial biogenesis, including the transcription factor Ppard, the PPARδ coactivator Pgc - 1α, and citrate synthase was greater in gastrocnemius muscles from IL - 15Rα — KO relative to B6129 control (Figure 5C); however, levels of these genes were unchanged in spleen and kidney (data not shown).

(C) Gene expression was greater for Ppard, Pgc - 1α, and citrate synthase in muscles from IL - 15Rα — KO mice, as determined by qPCR.

Related research (Pereira HJ, et al., 2012) used two different lines of evidence to explain the increase in the ratio of anteiso — to iso - branched alkenes that was observed during the transition from early to late stationary phase in M. luteus: structural studies of a key enzyme involved in fatty acid biosynthesis in M. luteus (FabH, or ß - ketoacyl - ACP synthase III) and transcriptional (whole - genome microarray) studies of M. luteus during different growth phases.

We determined the glycogen synthase (GS) activity; the content of glucose -6-phosphate, glucose, and glycogen; and the glucose transport in satellite cell cultures established from diabetic and control subjects.

Cyclooxygenase (COX, also referred to prostaglandin G / H synthase) is often the rate - limiting enzyme for the production of prostaglandins and thromboxanes from free arachidonic acid.

For example, in collaboration with James Dunford and Udo Oppermann at the University of Oxford, as well as Michael Arrowood at CDC and Eric Oldfield at U. of Illinois at Urbana Champain, we investigated the functions and structures of the C. parvum and P. vivax homologues of farnesyl pyrophosphate synthase, and found both parasite enzymes to produce different products from the human enzyme.

Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen synthase kinase 3; HD, Huntington's disease; hiPSC, human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R, Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting

Crystal structure of a tandem cystathionine - beta - synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 A resolution.

Mitochondrial membrane ATP synthase (F (1) F (0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.

Crystal structure of an indigoidine synthase A (IndA)- like protein (TM1464) from Thermotoga maritima at 1.90 A resolution reveals a new fold.

Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution.

For instance, exposure to light causes release of NO from mitochondria and also an increase in NO levels due to photoactivation of nitric oxide synthase.

A study from the Norwegian University of Science and Technology in Trondheim, reported that subjects with metabolic syndrome who followed a 16 - week HIIT routine lost twice as much of the fat - producing enzyme fatty acid synthase as compared to subjects who followed continuous moderate - intensity exercise.

(8) In another study, the anti-inflammatory properties of the active ingredient in schisandra, schisandrin, were shown to result from the inhibition of nitric oxide (NO) production, prostaglandin E2 (PGE2) release, cyclooxygenase - 2 (COX - 2) and inducible nitric oxide synthase (iNOS) expression.

They combined the phytoene synthase gene from maize with crt1 from the original golden rice.