Oxidative stress and redistribution of glutamine
synthetase in California sea lions (Zalophus californianus) with domoic acid toxicosis.
Eid T, Thomas MJ, Spencer DD, Runden - Pran E, Lai JC, Malthankar GV, Kim JH, Danbolt NC, Ottersen OP, de Lanerolle NC (2004) Loss of glutamine
synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy.
«In healthy subjects, it seems that the level of asparagine
synthetase in the brain is sufficient to supply neurons,» Michaud said.
Not exact matches
Human milk contains various enzymes; some are specific for the biosynthesis of milk
in the mammary gland (eg, lactose
synthetase, fatty acid
synthetase, thioesterase), whereas others are specific for the digestion of proteins, fats, and carbohydrates that facilitate the infant's ability to break down food and to absorb human milk.
Production of the enzyme asparagine
synthetase is deficient
in ALL and several other types of cancer cells, which are therefore unable to synthesize the amino acid asparagine.
When prompted, fragments of a tRNA
synthetase come together and charge a tRNA with a bio-orthogonal amino acid (N3), which is inserted as a recognizable tag into all subsequent proteins made
in the cell.
When prompted, the tRNA
synthetase charges a tRNA with the bio-orthogonal amino acid, which is then used by ribosomes to insert the tag into proteins made
in the cell.
Despite the substantial differences between these two classes of natural products, each is synthesized biologically under the control of exceptionally large, multifunctional proteins termed polyketide synthases (PKSs) and non-ribosomal peptide
synthetases (NRPSs) that contain repeated, coordinated groups of active sites called modules,
in which each module is responsible for catalysis of one complete cycle of polyketide or polypeptide chain elongation and associated functional group modifications.
Tony Wilkinson trained for his PhD with Alan Fersht at Imperial College London working
in protein engineering on tyrosyl tRNA
synthetase.
Fungal S - adenosylmethionine
synthetase and the control of development and secondary metabolism
in < i > Aspergillus nidulans % U http://www.sciencedirect.com/science/article/pii/S1087184512000679.
Schmied WH, Elsässer SJ, Uttamapinant C, Chin JW, «Optimized Pyrrolysyl tRNA
synthetase / tRNA expression and engineered eRF1 enable efficient multi-site unnatural amino acid incorporation
in mammalian cells ``, JACS, (2014)
Glutathione was measured
in NHLF cells following a 4 - hour treatment with buthionine sulphoximine (BSO, an inhibitor of gamma - glutamylcysteine
synthetase), electrophilic compounds including bardoxolone, sulforaphane and HPP - 1014, and non-electrophilic compounds, including CoPP and HPP - 4382.
In fact, most differentiated cells use glutamine
synthetase to bind excess ammonia to form glutamine [104].
Single nucleotide polymorphisms
in genes for 2» -5» - oligoadenylate
synthetase and RNase L inpatients hospitalized with West Nile virus infection.J Infect Dis.
BMAA has been demonstrated to be concentrated
in the brains of ALS patients (but not controls)
in Florida [19] and to be mis - incorporated into neuronal proteins via the L - serine tRNA -
synthetase system [20 — 22].
Genetic encoding and labeling of aliphatic azides and alkynes
in recombinant proteins via a pyrrolysyl - tRNA
synthetase / tRNA (CUA) pair and click chemistry.
In order for this activation to take place, the enzyme methionine adenosyltransferase (MAT, also known as S - adenosyl methionine
synthetase) breaks apart ATP to harvest from it a molecule of adenosine and then activates methionine by sticking adenosine onto it.
In addition to glycolysis, acetyl - CoA is produced from the oxidation of fatty acids by acyl - CoA synthetase enzymes in the outer mitochondrial membrane, and then transported into the inner mitochondrial matrix by acetyl L - carnitine for β oxidation and ATP productio
In addition to glycolysis, acetyl - CoA is produced from the oxidation of fatty acids by acyl - CoA
synthetase enzymes
in the outer mitochondrial membrane, and then transported into the inner mitochondrial matrix by acetyl L - carnitine for β oxidation and ATP productio
in the outer mitochondrial membrane, and then transported into the inner mitochondrial matrix by acetyl L - carnitine for β oxidation and ATP production.
«Glycogen
Synthetase Activity
in Skeletal Muscle: Interconversion of Two Forms and Control of Glycogen Synthesis.»
[79] Acquired susceptibility, for example, impaired glutathione
synthetase activity due to a RNA transcriptional error from haptenic binding and distortion of the mRNA complex or due to impaired and disordered protein synthesis due to low ATP production
in the cellular mitochondria would have similar adverse effects [80].
Watari T, Kaneshima T, Tsujimoto H, Ono K, Hasegawa A. 1998 Effect of thromboxane
synthetase inhibitor on feline infectious peritonitis
in cats.