Engineers, mathematicians, and physicists drawn to
synthetic biology need to grasp and develop broad knowledge in modern biology — and be able and willing to embrace biology's complexity and variability.
Not exact matches
In its final report, the committee will use this framework, revising as
needed, as a tool to provide the U.S. Department of Defense with an assessment of the concerns presented by
synthetic biology technologies and applications, as well as possibilities for mitigation.
Synthetic biology, she writes, has been addressing «humanity's
needs» — limitless fuel, for example — rather than «our
needs as individual, diverse and complex humans».
«So if you are interested in using the tools of
synthetic biology to create new pharmaceuticals, then you
need to have an idea of how... eukaryotes use pathways to create complicated molecules.
John Glass, a senior microbiologist in the
synthetic biology group at the J. Craig Venter Institute in Rockville, Maryland, puts it this way: If you can imagine a set of genes that will program a cell to do something — anything — then you can make them «at a reasonable cost and test your hypothesis... so it will be possible to attempt to design organisms that have extraordinary properties to solve human
needs.»
That means you'll
need to know some math, says Richard Kitney, a biomedical systems engineer who teaches
synthetic biology at Imperial College London (ICL) in the United Kingdom.
Yet much of the document in fact focused on the debatable desirability of the goals of
synthetic biology, and on the
need to acknowledge the complexities and uncertainties involved in designing novel living organisms — issues which concern many of those working in
synthetic biology and which can and should be the subject of open debate.
Security experts have long warned that would - be terrorists no longer
need to steal deadly pathogens when commonplace genetic engineering techniques could turn a benign microbe into a killer or
synthetic biology tools might be used to build a virus from scratch.
Although the commission saw no
need to call for a moratorium on
synthetic biology, it asked for careful risk monitoring, government oversight, public dialogue, ethics education, and «a continued culture of individual and corporate responsibility and self - regulation by the research community.»
In many respects,
synthetic biology — a field that «aims to apply standardized engineering techniques to
biology and thereby create organisms or biological systems with novel or specialized functions to address countless
needs,» as the U.S. Presidential Commission for the Study of Bioethical Issues defined it — is still very much in its infancy.
The authors explain the
need for new strategies in the conservation community to cope with the challenges of
synthetic biology.
Many extol the virtues of
synthetic biology as providing potential solutions to human health problems, food security, and energy
needs.
Long - term support is also
needed to address complex questions about how
synthetic biology could impact the environment and overcome communication barriers across disciplines, the report says.
According to the paper, the field of
synthetic biology — a discipline that utilizes chemically synthesized DNA to create organisms that address human
needs — is developing rapidly, with billions of dollars being invested annually.
But the burden of making
synthetic biology secure does not fall just on the scientists; policymakers and opinion leaders
need to endorse those plans, too, for the public to believe in the governance.
One does not
need to embark on a full - time degree to get started in
synthetic biology.
Some activists have criticized the report, saying more stringent controls on
synthetic biology are
needed.
«Our
synthetic biology pipeline for rapid sensor design and prototyping has tremendous potential for application for the Zika virus and other public health threats, enabling us to rapidly develop new diagnostics when and where they are
needed most.»
Finally, Pollard wants to close the loop by incorporating code - writing approaches, such as genome editing using CRISPR - based approaches and
synthetic biology, which are
needed to test and validate hypotheses and could also provide novel therapies.
Self - regulation is a good first step — but
synthetic -
biology companies still
need independent oversight.
Synthetic biology may have negative environmental impacts that
need to be monitored closely, said Allison Snow, a professor in the department of evolution, ecology and organizational
biology at Ohio State University.
BIOTECHNOLOGY: THE TIME is coming when if a new drug, cheap fuels or novel materials are
needed,
synthetic biology will deliver them.
Geneticist George Church discusses
synthetic biology, and why scientists
need to be careful with the technology.
Synthetic biology poses few risks because it is still in its early stages and there is no
need to impose new restrictions on, or temporarily halt, this type of research, says a report being released Thursday by the Presidential Commission for the Study of Bioethical Issues.
Government regulation is
needed to oversee the fast - developing
synthetic biology industry, according to two pioneers in the field, Harvard scientist George Church and genome researcher Craig Venter.
The report contained 18 recommendations designed to help ensure that, as
synthetic biology advances, the risks and ethical concerns are proactively addressed, the public is continually engaged, and oversight mechanisms are assessed and adjusted as
needed to protect public health and the environment.
When the
synthetic biology experts spoke, they focused on how their field is currently addressing the potential
needs for food, energy and medicine.
President Obama's bioethics commission has recommended that, for now, there is no
need for a moratorium or special oversight in the emerging field of
synthetic biology — research, much of it commercial, aimed at custom - designing fully functioning microorganisms.
But I don't believe we'll really
need those resources after a couple more decades (or fewer) of progress in
synthetic biology.