Specific activities include optimizing the conduct and oversight of gene transfer research, updating and interpreting biosafety policies under the NIH Guidelines Involving Research with Recombinant and
Synthetic Nucleic Acids, providing critical input on governmental policies regarding dual use research, the NIH Stem Cell Registry.
Antisense inhibitors are
synthetic nucleic acid drugs that can be designed to selectively bind to messenger RNA from the targeted, disease - linked gene, and inactivate it.
Not exact matches
«It's a type of molecule called an antisense oligonucleotide, or ASO, that essentially is
synthetic string of
nucleic acid that binds a specific sequence in the gene.»
Led by Dr. Peter Glazer, chair of therapeutic radiology, Dr. Mark Saltzman, chair of biomedical engineering, and Dr. Marie Egan, professor of pediatrics and of cellular and molecular physiology, the collaborative team used
synthetic molecules similar to DNA — called peptide
nucleic acids, or PNAs — as well as donor DNA, to edit the genetic defect.
Peptide
nucleic acid, a
synthetic hybrid of protein and DNA, could form the basis of a new class of drugs — and of artificial life unlike anything found in nature
«We identified a set of novel microRNAs that are potent inducers of neuroblastoma cell differentiation and found that mimics (
synthetic fragments of
nucleic acid used to raise microRNA levels in cells) of some of the identified microRNAs are much more potent in inducing neuroblastoma cell differentiation than the current differentiation treatments.
[6] Bioplex technology: Novel
synthetic gene delivery system based on peptides anchored to
nucleic acids.
«My favorite is the one we cited in the manuscript: «Viruses are entities whose genomes are elements of
nucleic acid that replicate inside living cells using the cellular
synthetic machinery and causing the synthesis of specialized elements that can transfer the viral genome to other cells.
Led by Dr. Peter Glazer, chair of therapeutic radiology, Mark Saltzman, chair of biomedical engineering, and Dr. Marie Egan, professor of pediatrics and of cellular and molecular physiology, the collaborative team used
synthetic molecules similar to DNA — called peptide
nucleic acids, or PNAs — as well as donor DNA, to edit the genetic defect.