Sentences with phrase «synuclein creates»
Amyloid - β clumps into whitish plaques, tau forms ribbons called tangles and α - synuclein creates fibrous deposits called inclusions.
https://www.scientificamerican.com/ Not exact matches
When compared to the enhanced alpha - synuclein production in the familial form of the disease, the modest effect created by the A to G mutation would be sufficient over a lifetime to increase the risk of PD, according to Soldner.
Every time the cell creates the alpha - synuclein protein, the tag gives off a light.
To start, they created two ways to systematically map the footprint of alpha - synuclein within living cells.
«In the second paper, we created a spatial map of alpha - synuclein, cataloging all the proteins in living neurons that were in close proximity to the protein,» explained Chee Yeun Chung, former Whitehead Institute Senior Research Scientist, who co-led both studies with Khurana.
They discovered that when α - synuclein fibrils are broken down, it often creates a smaller protein clump, which they named pα - syn * (pronounced «P - alpha - syn - star»).
«The effects of alpha - synuclein on mitochondria are like making a perfectly good coal - fueled power plant extremely inefficient, so it not only fails to make enough electricity, but also creates too much toxic pollution,» said Dr. Greenamyre.