Sentences with phrase «synuclein production»

The team found that measuring light was a reliable method to measure alpha - synuclein production.

With the new technology, the scientists hope to identifying ways to reduce alpha - synuclein production that can possibly prevent Parkinson's or its progression in patients diagnosed with the disease.

When compared to the enhanced alpha - synuclein production in the familial form of the disease, the modest effect created by the A to G mutation would be sufficient over a lifetime to increase the risk of PD, according to Soldner.

To see how the mutation affects alpha - synuclein production, the researchers identified two transcription factors that bind to the enhancer that carries this mutation.

Although one of the mutations has no effect, the other, which switches one nucleotide from an A to a G, slightly but significantly boosts alpha - synuclein production.

Not exact matches

Whether in a yeast cell or in a neuron, alpha synuclein directly interfered with the rate of production of proteins in the cell, and the transport of proteins between cellular compartments.

They found that by attaching to a mitochondrial protein called TOM20, alpha - synuclein prevented the mitochondria from functioning optimally, which resulted in the production of less energy and more damaging cellular waste.

With the help of a tailor - made viral vector they triggered production of human alpha - synuclein in rats.

«We wanted to find a drug that could turn down the production of α - synuclein,» he says.