Sentences with phrase «system activation in»

«Immune system activation in pregnant women can shape brain development in their babies: Stress and other factors can trigger immune response.»

Not exact matches

She is widely considered to be the international authority on the development and activation of lymphocytes in the immune system.

The Bitcoin protocol will be undergoing changes in the coming weeks related to the activation of the Segregated Witness system.

Prior to the development of a fully functioning nervous system, and the activation of said system, a human embryo is «alive» in the same sense a tumor is «alive»: the individual cells that make it up are alive, but there is no higher - level functionality.

The link between depression and the immune system has been shown using positron emission tomography using a tracer for the translocator protein (TSPO) showing increased immune activation in the brains of patients with major depressive disorder compared with control subjects.

We have previously described studies of pacing strategy using various experimental interventions, including faster and slower starts, higher temperatures, hypoxia, hyperoxia and altered energy substrate availability.1 We have proposed the presence of a complex, regulatory system that mediates changes to skeletal muscle motor unit activation and work rate in order both to optimise performance and prevent potentially harmful changes to homeostasis.

When exercise is self - paced and work rate is free to vary in response to external and internal physiological cues, then a complex system is proposed to be responsible for alterations in exercise intensity, possibly through altered activation of skeletal muscle motor units.

To investigate the effect of various parenting styles on kids» health, researchers at the University of Oregon examined saliva samples of 102 children who had an average age of 9 to look for levels of C - reactive protein, which measures general inflammation in the body, and secretory immunoglobulin A, which measures immune system activation.

They found that one particular style of parenting that ranks high on the poor parenting monitoring scale, which is sometimes referred to as «uninvolved parenting» (not knowing where kids are or what they're doing; not disciplining; not showing warmth or being involved in kids» lives) was associated with higher immune system activation.

McLean Hospital neuroscientists have found that immune system activation during pregnancy and right at birth can cause alterations in the brain's neural circuits during young adulthood that are consistent with behavioral symptoms common in autism spectrum disorder (ASD) and other developmental conditions.

«In contrast to RNA interference, which is commonly used to inactivate gene activity, the CRISPR - on system allows activation of cellular genes.

«From a clinical point of view, irisin and FGF21 represent a cold - stimulated hormone system, which was previously unknown, and may be harnessed in future obesity therapeutics through brown fat activation.»

The underlying mechanism involves the activation of the immune system, resulting in local inflammation and proliferation of skin cells.

If any of the adult shark pooh - pooh - ers had been having their brains scanned at that moment, scientists would have seen increased activation in the amygdala and insula — two key parts of the brain's limbic system and important inputs to the mesocortical limbic circuit.

Activation of these receptors led to a «massive mobilisation» of myeloid - derived suppressor cells (MDSCs), which play a crucial role in lowering the immune system response back down to normal levels (European Journal of Immunology, DOI: 10.1002 / eji.201040667).

«Our studies imply that the change of oxygen levels in different tissues can be sensed by Treg cells and that this process is critically important for maintaining the correct balance between activation and suppression of the immune system,» says Liu.

Allison's seminal work focuses on a protein called CTLA - 4, which reins in T - cell activation in the immune system.

The R2TP system and the HSP90 chaperone are crucial for the assembly and activation of mTOR and other related kinases, but how this happens in cells is still somewhat of a mystery.

Óscar Llorca and his team have used this technique to learn about the structure and functioning of a complex system called R2TP, which is involved in various key processes for cell survival such as the activation of the kinases mTOR, ATR and ATM, proteins that are the target of various cancer drugs currently being developed.

Most importantly, the doxorubicin - decorated diamonds had no effect on white blood cell count, an indicator of immune system activation that's often the deciding factor in whether a patient can continue chemotherapy.

Another study found that vivid visualization accompanied by emotion triggered more activation in visual processing systems than did images alone.

This triggers a domino effect in the cell's defense system, resulting in the activation of the enzyme caspase - 1, which ultimately causes the induction of pyroptosis, a fiery form of cell suicide.

Greg Murray and colleagues compared activation of the brain's reward system in 16 men during a gambling task at 10 a.m., 2 p.m. and 7 p.m..

Researchers at the University Department of Radiology and Nuclear Medicine at the MedUni Vienna have now demonstrated by means of a meta - analysis of functional image data that increased activations in the involuntary attention system in the brain are responsible for these disorders in MS patients.

In contrast to this picture, the vast majority of HIV - infected AIDS patients, both adults and children, display all the signs of chronic activation of the immune system.

«This study shows that trauma care systems need to modify their conventional approach to activation to enable early recognition of these infants and swift escalation up to «major trauma patient» status in order to minimise delays to delivery of definitive care,» they write.

This is an illustration showing interactions between components of the AH10 - 7 compound (yellow), an immune system antigen - presenting cell (gray), and an invariant natural killer T cell (green and blue) that spark activation of iNKT cells in «humanized» mice.

(A) n important part of this regulatory process is not only allowing activation but also making sure the entire system is switched off in the absence of infection.»

«Our results suggest that ongoing cytokine activation in the nervous system can contribute to the persistent symptoms of fatigue, pain, and cognitive dysfunction that patients sometimes experience despite having been treated for Lyme disease.»

In the future, the scientists plan to use this system to study the effect of these and other compounds that may prevent the activation of HIV - 1 in the braiIn the future, the scientists plan to use this system to study the effect of these and other compounds that may prevent the activation of HIV - 1 in the braiin the brain.

But inappropriate activation of interferon signaling can cause the immune system to attack healthy tissues in the body, leading to a variety of autoimmune diseases.

The orphan drug she received, Eculizumab, is a monoclonal antibody capable of blocking activation of the body's complement system, a group of proteins in the blood that are ultimately responsible for the damage to the transplanted organ.

Patients in the study were treated with immune checkpoint inhibitors that block the activation of PD1, a protein on immune system T cells that halts immune response.

Advances in electron microscopy and native mass spectrometry enabled the researchers to determine that a critical component of the signaling system, anchored protein kinase A, remains intact during activation.

Created with other blood cells in the bone marrow, they interfere with activation and proliferation of T cells, the immune system's attack cells.

In another series of tests, the researchers tested whether oxytocin enhances the activation of the reward system only when seeing the partner or whether there is a similar effect with pictures of acquaintances and female work colleagues of many years.

«A growing body of evidence suggests that immune system activation, such as that caused by bacterial and viral infections, can play important roles in many brain disorders,» explained William Carlezon, PhD, chief of the Division of Basic Neuroscience at McLean Hospital, and senior author of the paper.

McLean Hospital neuroscientists have found that even a brief episode of immune system activation within days of birth can cause persistent changes in sleep patterns concurrent with increases in epilepsy - like brain activity — a combination of symptoms common in autism spectrum disorder (ASD) and other developmental conditions.

The investigators also measured gene expression of postvaccinated cervical cells in three of the patients and found increased expression of several genes (CXCR3, Tbet and IFNβ) associated with activation of the immune system.

Carlezon, who is a professor of psychiatry at Harvard Medical School, and his team discovered that temporary immune system activation shortly after birth produced two main findings in the adult mice.

The infection rapidly turned on a wide range of genes involved in immune system activation and cell death, they conclude, bolstering the hypothesis that the greatest harm may not have been done by the virus itself, but by an over-reactive immune system.

The trauma and damage associated with football participation may also be linked to elevations in blood pressure through immune system activation and inflammation.

«One of the least understood aspects of this process is how the excess milk and large numbers of dead cells are removed from the mammary gland without substantial activation of the immune system,» says Matthew Naylor, a cancer biologist at the University of Sydney in Australia.

In order to maintain a healthy weight, reward system activation needs to be «just right.»

MUS81 plays an essential role in this killing of cancer cells because nuclear DNA was not cut in cancer cells that lacked the enzyme and no activation of the immune system was observed in these cells.

Be it snow on a slope that can sit there for days before being sent descending by an overambitious skier or bonds in macromolecules that change dramatically upon appropriate activation — systems that reside for extended periods of times in one state before switching rapidly to another, energetically more favourable one are found in many different contexts.

In the brain, it led to chronic activation of the immune system, even long after the viral infection had been cleared.

While the activation of the voxels varies randomly during other parts of the film, at each of the 15 key moments certain voxels are in the same position for each viewer and form an identical fingerprint pattern,» describes Iiro Jääskeläinen, Aalto University professor in systems neuroscience.

Now, researchers led by Susumu Ishida and Atsuhiro Kanda at Hokkaido University's Graduate School of Medicine have shown that the activation of the receptor - associated prorenin system (RAPS) is involved in the pathogenesis of uveitis.

«We can clearly demonstrate that the activation of the secretion system is the main function of the protein EIIAGlc, while the many other described metabolic functions play a minor role in the occurrence of illness,» says Bumann bringing his findings to the point.