Sentences with phrase «system cell type»

An international research team headed by the rheumatologist Dr Andreas Ramming at Friedrich - Alexander - Universität Erlangen - Nürnberg (FAU) has now managed to identify an immune system cell type that can be used in a targeted attempt to control the inflammatory response in arthritis patients.

To account for individual differences in cell types, such as that potentially produced by a shift toward pro-inflammatory innate immune system cell types, a regression calibration approach similar to that developed by Houseman et al. (2012) was performed.

Not exact matches

It's a type of cancer immunotherapy, which harnesses the body's immune system to take on cancer cells.

In the case of teh bacterial flagellum, removal of some of the «well matched parts» turns it into a type III secretory system which allows gram negative bacteria to translocate proteins directly into the cytoplasm of a host cell.

Also amazing is the way the immune system distin - guishes between foreign sub - stances and the hundreds of cell types that make up our body.

The robust digital load cell type SDLX is produced in stainless steel and designed for the extremely though environment in lift systems for waste management with shock loads and vibrations.

This type of diabetes strikes in the early teenage years and begins with the immune system destroying the cells in the pancreas that produce insulin, according to Patrick Holford, founder of the Institute for Optimum Nutrition in London.

In the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in general.

For unknown reasons our immune system attacks healthy cells, tissues and organs in a process called autoimmunity, which can result in diseases such as multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis.

A type of immune therapy known as PD - 1 blockade controlled cancer in 77 percent of patients with defects in DNA mismatch repair — the system cells use to spell - check and fix errors in DNA (SN Online: 10/7/15).

Macrophages are a type of white blood cell critical to the innate immune system.

We now know the virus attacks a person's T lymphocytes, a type of white blood cell that plays a central role in the immune system.

Plath's team found that the changes that happen in cells during reprogramming occur in a sequential stage - by - stage manner, and that importantly, the stages were the same across all the different reprogramming systems and different cell types analyzed.

This system plays a major role in the regulation of gene activity, and enables the selective expression of different functions in differentiated cell types.

This study, «Engineered epidermal progenitor cells can correct diet - induced obesity and diabetes,» is the first to show that an engineered skin graft can survive long term in wild - type mice with intact immune systems.

Patients with metastatic non-small cell lung cancer will always progress after chemotherapy, so most patients go on to be treated with immunotherapy, a type of therapy that uses the body's immune system to fight cancer.

A second type of immune system cell, called regulatory T cells (Tregs), are a model of constancy, remaining stable even as Teffs go into battle mode.

Although the types of nerve cells involved in the two systems maybe very different, the circuit patterns are highly likely to be similar.

Normally, the cells Nobel used for the test would divide and give rise to a specialized type of cell in the central nervous system called an oligodendrocyte.

Two different types of dendritic cells in the immune system present antigen in different ways to elicit distinct immune responses.

Action potentials can be created by many types of cells, but are used most extensively by the nervous system for communication between neurons and to transmit information from neurons to other body tissues such as muscles and glands.

One advantage of this method is that it only activates a certain type of immune cell, the dendritic cell or T - cell, and only in one part of the body, near the draining lymph nodes or tumor, which helps cut down on the system - wide side effects often seen with chemotherapy.

Type 1 diabetes, which usually starts in childhood, is an autoimmune disease in which the immune system attacks the body's own beta cells.

Researchers at Penn State have combined the two approaches by taking biodegradable polymer nanoparticles encapsulated with cancer - fighting drugs and incorporating them into immune cells to create a smart, targeted system to attack cancers of specific types.

The Duke researchers who made this discovery say it may help explain how a relatively small number of genes can create the dazzling array of different cell types found in human brains and the nervous systems in other animals.

«We want to start looking system by system to see how widely acting this process is on different types of cells,» he says.

Type 1 diabetes, formerly known as juvenile diabetes, is characterized by the immune system's destruction of the beta cells in the pancreas.

In the presence of Acinetobacter and Akkermansia, they became a particular type of T helper cell, which trigger inflammation and help the immune system kill off invaders or infected cells, the researchers report today in the Proceedings of the National Academy of Sciences (PNAS).

The olfactory system comprises six million to 10 million receptor cells (of which there are nearly 400 different types) and links to multiple brain structures and neural pathways, including those involved in memory, emotion and movement.

The four children also had more of the types of species that are known to trigger gut inflammation, a possible prelude to type - 1 diabetes, in which the body's immune system mistakenly produces antibodies that attack and destroy the beta cells of the pancreas that normally make insulin.

The T - lymphocytes, or T - cells, are a particular type of white blood corpuscle that is important to the immune system.

Type 1 diabetes occurs when the body's immune system destroys the cells making insulin, the substance that enables glucose in the blood to gain access to the body's cells.

But roundworms seem to shift the balance of the immune system towards producing more type 2 T cells.

In type 1 diabetes, beta cells in the pancreas that make insulin — the hormone that keeps our blood glucose levels at a safe concentration — are destroyed by the immune system.

Beyond lung cancer, TiY is able to target TICs in 28 types of human cell lines derived from the central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer.

The virus appears to invade the brain by infecting a type of glial cell called olfactory ensheathing cells (OECs), which nourish smell - sensing neurons and guide them from the olfactory bulb to their targets in the nervous system.

They've figured out how to turn human stem cells into functional pancreatic β cells — the same cells that are destroyed by the body's own immune system in type 1 diabetes patients.

The researchers studied two types of cells called effector T cells, which activate the immune system to defend our body against different pathogens, and regulatory T cells, which help control the immune system and prevent it from attacking healthy parts of its environment.

However, this coupling does not exist in cell culture models with exogenously expressed c - MYC — the type of systems that are mainly used to investigate glutamine addiction in cancer.

The smart window controls the transmission of visible light and infrared heat into the building, while the new type of solar cell uses near - UV light to power the system.

One likely reason for this is that animals undergo cellular differentiation; human life begins as a single cell that differentiates into the various cell types needed for different organs, body parts, blood, the immune system, etc..

But exactly how the immune system works remains, in many ways, a mystery, as there are numerous cell types whose functions and interactions with our immune systems have not been well understood.

During the initial phase, a relatively aggressive inflammation response occurs, and several types of cell from the immune system are attracted to the wound.

Because pAPCs train T cells according to their kind, the shift in their cell type also caused a shift in the types of T cells that left the lymphatic system and traveled back to the gut.

«When you look at the varying types of cell morphologies that correspond to different leukemias, you can statistically look at enough cells using this system to be able to classify different kinds of leukemias,» says Yousaf.

UC in May 2012 filed a patent for Doudna, Emmanuelle Charpentier (then of Umeå University in Sweden), and their colleagues for their discovery that CRISPR, an immune system used by bacteria, could serve as a genome - editing tool in any type of cell.

The transplanted stem cells differentiated to different types of cells with variable level of maturation, specific for the nervous system.

The drug's mechanism of action was entirely new: Instead of attacking cancer cells (like chemo), or indiscriminately revving up the immune system (like IL - 2), ipilimumab blocked a single receptor on one type of immune cell.

After initiating photoreceptor loss in the fish retinas, the researchers monitored the immune system's response by tracking the activity of three types of fluorescently labeled immune cells in and around the eye: neutrophils, microglia and peripheral macrophages.

New technologies are coming to the fore that allow interrogation of the types of cells interacting with tumors, in particular providing intelligence on the broad variety of complex associations between tumor cells and the immune system.