Sentences with phrase «system cells called»

Inflammatory Bowel Disease or IBD is an immune system disorder common in PWDs in which the intestinal lining becomes overrun with immune system cells called lymphocytes and plasmacytes.

In their latest work, reported online in the Journal of Clinical Investigation, the scientists analyzed blood from such mice and identified two types of autoimmune response directed specifically against the protein, with the first response directed by a specialized kind of immune system cells called T cells and the second by antibodies.

Without it, immune system cells called T cells, B cells and natural killer cells do not develop normally.

This makes it impossible for sugars on the surface of immune system cells called T cells to attach in multiple spots at once and trigger inflammation.

The study included 124 newly diagnosed patients at 25 clinical trial sites in the U.S. Two - thirds of the patients were treated with ICT - 107, an experimental vaccine based on immune system cells called dendritic cells that were exposed to six synthetic proteins, or antigens, known to be involved in GBM development.

And researchers must figure out how to build in some core features: the necessary blood vessels, immune - system cells called microglia and connections from other brain regions, such as the thalamus and cerebellum.

In a related paper published online today in Nature Biotechnology, Konrad Hochedlinger of the Harvard Stem Cell Institute in Cambridge and his colleagues compared the gene expression patterns in mouse iPS cells derived from white blood cells, muscle precursor cells, immune system cells called B cells, and fibroblasts taken from tail tips.

Not exact matches

The athletic adults also appeared to have healthier and younger - looking immune systems, at least when it came to an organ called the thymus that's responsible for generating key immune cells called T cells.

Hoping to learn something about how the human body defends itself against cancer, he had zeroed in on a complex regiment of lymphocytes called T cells, common to the immune systems in both mouse and man.

Some geolocation systems use GPS and cell site triangulation (and in some instances, local Wi - Fi networks) in combination to zero in on the location of a device; this arrangement is called Assisted GPS.

She called for «a full plan for fixing the vulnerabilities we are finding — from overloaded 911 systems to out of service cell sites.

If you need to make international calls, want to save on your monthly minutes, or have all your phone numbers (home and cell) integrated into one system, Google Voice is a good option.

Tesaro has a coveted position as a leader in the so - called immuno - oncology sector, which harnesses the body's own immune system to combat cancer cells.

Sam created high - performance semiconductor chips and related software with low power usage algorithms that dramatically improved voice and sound quality in cell phones, video phones, desktop phones, conference call phones and automotive communication systems.

Higher animals all seem to contain at least one such society, called a «living person,» present in the body in addition to the cells and molecules of the central nervous system, even though dependent upon them.

Given a system or composite of individuals, all on a comparable level, for instance molecular or cellular, then in some cases, given integration of activities (thus molecules in a cell, or cells in a vertebrate animal), there may be what Leibniz called a «dominant monad» or what Whitehead calls a «society of presiding occasions.»

Health service chief calls for affordable access to CAR - T, which modifies immune system to destroy cancer cells

The researchers used a drug called clorgyline to inhibit the activity of the MAOA enzyme; the drug disrupted the signaling system that led to cancer cell invasion and proliferation.

A decade ago a drug based on an internal protein of the flu virus, called NP (for nucleoprotein), set the immune system's killer T cells into action, but it only partially protected mice from the flu.

For unknown reasons our immune system attacks healthy cells, tissues and organs in a process called autoimmunity, which can result in diseases such as multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis.

Our research enhances the traditional understanding of the plant defense system and describes a new concept describing how plants protect themselves against the pathogens that grow in the space outside plant cells (the apoplast)-- a new concept called effector - triggered defense or ETD.»

The treatment, called CAR - T immunotherapy, uses genetically engineered T cells, immune system fighters usually tasked with identifying invaders in the body,...

Some scientists had claimed that the lymphatic system was derived from specialized stem cells called angioblasts, whereas others had argued that it originated by the differentiation of pre-existing embryonic veins.

The technique examines the small molecules, or metabolites, within cells, bio-fluids, tissue, or organisms and their interactions within the larger system, called a metabolome.

The immune system depends on molecules called T cell receptors on the surface of T cells to recognize and respond to foreign antigens from virus - infected cells, tumors and other threats.

But during pregnancy, the fetus is protected from the mother's immune system by the placenta, which has specialized cells — called trophoblasts — that can burrow into the mother's body without exciting an attack by the immune system.

In this study, the SIgN team discovered for the first time that the integrity of p53 affects the production of a special cell surface protein called Major Histocompatibility Complex (MHC) class I. MHC class I molecules on the cancer cell surface serve as targets for the immune system.

«We found that a protein expressed by gut bacteria called Bacteroides works to prevent IBD by rapidly recruiting white blood cells to kill a cell of the immune system that is responsible for orchestrating IBD,» says McCoy.

A second type of immune system cell, called regulatory T cells (Tregs), are a model of constancy, remaining stable even as Teffs go into battle mode.

The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to test the idea of stimulating the immune system's killer T cells to hunt for the virus more aggressively, in this case using a weakened form of the cold virus to carry three genes from HIV.

Normally, the cells Nobel used for the test would divide and give rise to a specialized type of cell in the central nervous system called an oligodendrocyte.

Using a surgical technique called parabiosis to join the circulatory system of a young mouse with that of an old one, the researchers studied the effects of young blood on elderly cells, and vice versa.

The system, says Brahmer, provides a kind of «handshake» or connection between receptors on immune cells, called PD - 1, and their sister - proteins on tumor cells, called PD - L1.

Finally, the team grew the tissue in a three - dimensional system, which coaxed it into forming all the structures found in gut tissue, including the finger - like villi that protrude inwards to increase surface area, and recesses called crypts containing the intestinal stem cells that renew the gut lining weekly (Nature, DOI: 10.1038 / nature09691).

These peptides also have another critical ability that sets them apart from traditional antibiotics: They can recruit the host's immune system, summoning cells called leukocytes that secrete chemicals that help kill the invading microbes.

Allison's seminal work focuses on a protein called CTLA - 4, which reins in T - cell activation in the immune system.

Dr. Cripe and his colleagues at The Ohio State University, the University of Pittsburgh School of Medicine and Cincinnati Children's Hospital Medical Center tested how well the oncolytic viral therapy — a cancer - killing form of the herpes simplex virus, called oHSV — infected and killed tumor cells in mice with and without a healthy immune system.

An animal's immune system detects foreign cells by scanning for proteins, called antigens, that stick out from the surface of each cell.

Others include transplanting so - called Schwann cells from peripheral nerves, using growth factors to stimulate nerve growth, and boosting the immune system in the damaged area (New Scientist magazine, 14 August 1999, p 36).

Óscar Llorca and his team have used this technique to learn about the structure and functioning of a complex system called R2TP, which is involved in various key processes for cell survival such as the activation of the kinases mTOR, ATR and ATM, proteins that are the target of various cancer drugs currently being developed.

The virus appears to invade the brain by infecting a type of glial cell called olfactory ensheathing cells (OECs), which nourish smell - sensing neurons and guide them from the olfactory bulb to their targets in the nervous system.

The researchers studied two types of cells called effector T cells, which activate the immune system to defend our body against different pathogens, and regulatory T cells, which help control the immune system and prevent it from attacking healthy parts of its environment.

The patients received biweekly infusions of nivolumab, which is an antibody that blocks a protein called PD - 1 on the surface of immune system T cells.

By manipulating the function of certain immune cells, called T cells, researchers could help restore the system's balance and create new treatments to target these diseases.

Smoke inhibits activity of so called mast cells, which drive the immune system's response to allergens.

Rick Maizels at the University of Edinburgh and his colleagues find that the worms manipulate their hosts into producing cells called regulatory T cells, which calm the immune system.

As part of this system, two enzymes called Rag1 and Rag2 cut apart and rearrange DNA within immune cells, helping to create the body's millions of unique antibodies and T cell receptors — each specific for a particular microbe.

The pain drug they found binds to a receptor on cells throughout the central nervous system called the sigma 2 receptor.

In addition to suppressing the mature blood cells battling against the infection, malfunctioning of this signaling system results in permanent damage to the body's blood producing cells — called hematopoietic stem cells — that are located in the bone marrow.

In a study to be published in Psychological Science, researchers from Aarhus University and the University of Copenhagen demonstrate that brain cells in what is called the mirror system help people make sense of the actions they see other people perform in everyday life.