In a report to be published in the journal
Cell Host & Microbe online June 11, researchers showed that immune -
system - triggering TB proteins, or antigens, were able to prompt a larger, prolonged immune
system response just by being transported from infected dendritic
cells to
uninfected ones.
The Polonis lab has also employed both
cell line - based model
systems, as well as primary
cell types from
uninfected humans, to investigate virus - antibody - host
cell interactions and cross-subtype reactivities amongst the major subtypes of the HIV pandemic.