Sentences with phrase «system disease called»

They can also develop chronic ear infections, skin cysts, degenerative hip disease, and a serious, untreatable nervous system disease called Progressive Neuronal Abiotrophy or PNA.

Not exact matches

This recipe calls for a wonderful blend of strawberries, blackberries, and raspberries, which are high in phytonutrients that reduce inflammation, boost the immune system, and make it hard for chronic diseases to thrive in the body.

Those who are severely affected have an autoimmune disease called celiac where the villi in the small intestine are damaged by the immune system, so food isn't absorbed correctly leading to all sorts of problems within the body.

The easily digestible liquid is full of unique disease - fighting antibodies called immunoglobulins that strengthen your baby's immune system.

He added that the method used in this study, called «network biology» — where computer systems are used to identify gene networks that work together to underpin disease — may also help find treatments for other conditions.

For unknown reasons our immune system attacks healthy cells, tissues and organs in a process called autoimmunity, which can result in diseases such as multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis.

One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune system, new research suggests.

The initiative, called Safe Genes, comes at a time when so - called «gene drive» systems, which override the standard rules of gene inheritance and natural selection, are raising hopes among some scientists that the technology could alter or suppress populations of disease - carrying insects or other pests in as few as 20 generations.

Diseases where the immune system reacts to the body itself are called autoimmune diseases.

These so - called endometrial organoids promise to shed light onto the processes that occur during the monthly menstrual cycle and open up the possibility of studying diseases of the uterus, such as endometrial atrophy (thinning of the lining) or cancer, in a lab culture system.

The test could enable earlier diagnosis of a group of degenerative brain diseases called synucleinopathies, which include Parkinson's disease, Lewy Body dementia, and multiple system atrophy.

By manipulating the function of certain immune cells, called T cells, researchers could help restore the system's balance and create new treatments to target these diseases.

Neurofibromatosis is one of at least 60 genetic diseases called neurocutaneous disorders that involve the skin, central nervous system, and / or peripheral nervous system, according to a comprehensive review article in the journal Current Neurology and Neuroscience Reports by neurologists at Loyola University Medical Center and Loyola University Chicago Stritch School of Medicine.

Grillner had severed the cats» spines, rendering them paralyzed, and then injected them with an amino acid called L - dopa, routinely used to treat Parkinson's disease — a neurodegenerative disorder of the central nervous system characterized by motor symptoms.

In recent years, the study of human biology has been shaken up by discoveries of how the bacteria that live in the gut, the so - called microbiome, affect metabolism, the immune system, and disease progression.

Looking for immune abnormalities throughout the lifespan of the mice, the group found that most immune system components stayed the same in number, but a type of brain - resident immune cells called microglia that are known first responders to infection begin to divide and change early in the disease.

To peel away at the intricate layers that govern the development of neurons, a research team led by Chaolin Zhang, PhD, Assistant Professor in Systems Biology and Biochemistry and Molecular Biophysics and Hynek Wichterle, PhD, Associate Professor in Pathology & Cell Biology, Neuroscience, and Neurology, at the Center for Motor Neuron Biology and Disease, Columbia University Medical Center, focuses on a level of molecular regulation called alternative splicing.

His work suggests that a feisty immune defense — as measured by the quantities of certain proteins called cytokines — allows survival in the face of infectious diseases; but it might also hamper fertility because a woman's immune system must temper its reaction to a growing fetus in order for a pregnancy to succeed.

Celiac disease is an autoimmune disease where special immune system cells, called gluten - specific T cells, have an extraordinarily strong inflammatory reaction to gluten.

Interestingly, these changes are related to the so - called PINK1 - Parkin pathway that is responsible for the mitochondrial quality control system and implicated in Parkinson's disease.

The disease is caused by a faulty copy of IL2RG, a gene that codes for an immune system protein called interleukin 2.

These proteins, called antigens, serve as a signal to the immune system that a diseased or cancerous cell is present and needs to be eliminated.

Allergens are usually proteins (called antigens) found in a non-infectious allergy - causing substance (for example pollens or dust mites), which ultimately trigger the immune system to respond in a way that can be harmful, causing tissue damage and serious disease.

Osteoarthritis (or OA, also called «wear and tear arthritis») in the past has been classified differently from a disease such as rheumatoid arthritis (RA) which is characterized by system - wide inflammation and autoimmune responses which attacks joint tissue.

Columbus, OH (Scicasts)-- One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune system, new research suggests.

The findings have implications for the design of cancer vaccines and what are called adoptive T cell therapies; when T cells are collected from a patient and grown in the laboratory, increasing in number before they are given back to the patient to help the immune system fight disease.

Often called «bubble boy disease,» SCID devastates the immune system and leaves patients vulnerable to lethal infections.

Multiple sclerosis (MS) is a disease in which the body's immune system attacks and destroys the protective covering of the nerves, called the myelin sheath, through a process called demyelination.

If it does, then you might use the approach of making more beta cells right at early onset of the type 1 disease to try and stop or reverse the immune attack, making the immune system think its made a mistake, inducing something called anergy by making more beta cells.

1986 — Developed the Initial HIV Disease Classification & Staging System — In 1986, the US Army adopted a staging classification for HTLV - III infection called «The Walter Reed (WR) Staging Classification System.»

Then for postdoctoral research I moved to Yale University, where I worked in a lab that looked at all kinds of different disease areas using the approaches of a field called chemical biology, which is using small molecules — chemicals — to probe biological systems in the hopes of developing compounds that could be new drugs.

In the rare, life - threatening disease called paroxysmal nocturnal hemoglobinuria (PNH), patients are stricken with chronic anemia and blood clots, when the oldest part of the immune system — known as complement — turns against its own red blood cells, or erythrocytes.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

We are studying how a protein called NMNAT2 provides neuroprotection in the mammalian central nervous system with a long - term goal of developing therapies to treat neurodegenerative diseases, including Alzheimer's disease and tauopathies.

At a second level, the intelligent analysis of data provided by the first level, supported with a disease management system will allow the neurologist in charge to access accurate and reliable information to decide about the treatment that best suits the patient, improving the management of their disease, in particular to adjust so called therapeutic window.

Specifically, the authors call for systems biology approaches (using large data sets and modeling to understand complex biological systems) to fill critical knowledge gaps in understanding how Mycobacterium tuberculosis (Mtb) infection causes disease.

The study specifically targets two different types of brain cells, called microglia and astrocytes, that work to keep the immune system in check and clear out old and damaged cells, preventing disease.

Right now we call the practice of medicine «health care,» but consider these facts about what is actually — if you really think about it — a «disease care» system:

Ageing is just a natural process that might show up at any age and which is reflected not only by the modifications in our body appearance, but more importantly by the internal signs proving a gradual deterioration in our inner body ability to ensure an optimal metabolism and physiology, to keep a strong immune system and consequently to prevent and fight the chain of degenerative chronic diseases, also called age - related diseases.

The antibody produced by the immune system in response to Graves» disease is called TRAb or thyrotropin receptor antibody.

This is actually beneficial, I think — it is called «intermittent fasting» and should promote longevity and immunity to bacterial and viral infections of the central nervous system, which are probably responsible for dementia, Parkinson's, and other diseases of aging.

We show signs of weak immune systems (variations of primary immunodeficiency, CVID), and «extra» allergies and sensitivities (now known to be mostly from a newly and thus still poorly recognized widespread mast cell activation disease called MCAS, ICD - 10 code coming October 2016, read «Never Bet Against Occam» by L. Afrin, MD), as well as all manner of endocrine imbalances (esp low thyroid, and often adrenal fatigue), some mitochondrial disease and / or dysfunction and all manner and forms of dysautonomia, but especially POTS in the more severe cases.

Many evergreen trees give off aromatic compounds called phytoncides that increase natural killer (NK) cells, your immune system's lead defense against viruses and disease.

More than 90 percent of hypothyroid cases in the United States are caused by an autoimmune disease called Hashimoto's, in which the immune system attacks and destroys the thyroid gland.

Pernicious anemia is an autoimmune disease in which the immune system attacks a compound in the stomach called intrinsic factor, which is necessary to absorb B - 12.

In my experience recovering from bartonella, one of the Lyme disease co-infections, requires combination herbal or prescription antibiotics, steps to boost the immune system, and supplements to decrease inflammation caused by chemicals called cytokines.

In my experience recovering from babesia, one of the Lyme disease co-infections, requires combination herbal or prescription antibiotics, steps to boost the immune system, and supplements to decrease inflammation caused by chemicals called cytokines.

An overreactive immune system is one of the causes of autoimmune disease, not to mention if your immune system is always on call it can't fully tend to its other duties, like scavenging for abnormal cells.

This recipe calls for a wonderful blend of strawberries, blackberries, and raspberries, which are high in phytonutrients that reduce inflammation, boost the immune system, and make it hard for chronic diseases to thrive in the body.

Since many people associate rashes with allergies, it's not a far stretch when people call dermatitis herpetiformis a form of «gluten allergy,» although it's not a true allergy — like celiac disease, dermatitis herpetiformis is autoimmune in nature (indicating an attack by your own immune system in response to gluten ingestion).