LEMP in Leonbergers is a paritally penetrant autosomal recessive central neverous
system disease resulting from an amino acid change within the LEMP gene.
LEMP in Rottweilers is a autosomal recessive central neverous
system disease resulting from a 1 basepair insertion within the LEMP gene; cincal signs may develop as early as 1 year of age.
Not exact matches
He says that having a single device to determine — or at least rule out — the
disease in a non-invasive manner that delivers immediate
results would have a huge impact on the patient and the entire medical
system.
Cage - free
systems give hens more room to move around but also
result in higher feed costs, lower egg production per bird, increased cannibalism among the flock and greater vulnerability to
diseases, according to a report by agricultural consultant Promar International.
One that is probably not already mentioned here: Because tattoos are a
result of injecting foreign chemicals into your body, they undermine the immune
system, which is a great way to increase the possibility of getting cancer and other
diseases.
There is a growing realisation that chronic
disease is a
result of inflammation in our digestive
system.
Breastfed infants, compared with formula - fed infants, also seem to have stronger immune
systems to fight infection,
resulting in lower rates of chronic childhood
diseases, such as diabetes, celiac
disease, inflammatory bowel
disease, childhood cancer, and allergies and asthma.
Parents are normally worried about babies» eating hands since they think it is the main cause
resulting in contagious
diseases and weakening the antibody
system.
In rare cases, failure to gain weight can turn out to be a
result of a lung problem, such as cystic fibrosis; a nervous
system problem, such as cerebral palsy; a chromosome problem, such as Down syndrome; heart
disease; anemia; or a metabolic or an endocrine disorder, such as growth hormone deficiency.
Physiologic sleep studies have found that breastfed infants are more easily aroused from sleep than their formula - fed counterparts.247, 248 In addition, breastfeeding
results in a decreased incidence of diarrhea, upper and lower respiratory infections, and other infectious
diseases249 that are associated with an increased vulnerability to SIDS and provides overall immune
system benefits from maternal antibodies and micronutrients in human milk.250, 251 Exclusive breastfeeding for 6 months has been found to be more protective against infectious
diseases compared with exclusive breastfeeding to 4 months of age and partial breastfeeding thereafter.249
Rheumatoid arthritis (RA) is a chronic autoimmune
disease that occurs when the immune
system attacks the body instead of defending it, causing inflammation that often
results in serious damage to bones, joints and tendons, and can also affect internal organs like the heart, eyes and lungs.
The study also shows that people who had low cortisol levels, on average, have had their
disease longer than those with high cortisol levels, which could suggest that chronic stress in bipolar disorder can lead to an «exhaustion» of the stress
system with reduced cortisol levels as a
result.
For unknown reasons our immune
system attacks healthy cells, tissues and organs in a process called autoimmunity, which can
result in
diseases such as multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis.
The end
result is that this is one of those very rare
diseases — there's hardly another like it — where the virus multiplies continuously at high levels and the immune
system is unable to deal with it.
The
results of this study suggest that Nodding syndrome may be an autoimmune
disease, in which the immune
system incorrectly attacks the body's own proteins.
«It has profound implications for our understanding of human development and physiology, and gives us a remarkable wealth of resources to examine how disturbances of this
system might
result in
diseases such as cancer.»
The highest risk of death was seen among patients with multiple
system atrophy with parkinsonism, followed by patients with dementia with Lewy bodies, Parkinson
disease dementia and Parkinson
disease, according to the
results.
While prioritization of resources for each issue or
disease is necessary, it is also essential to embrace a
systems - focused approach to capacity building and partnership to achieve
results more comprehensively.
Neuroscientists are optimistic that the success of nusinersen may portend similar positive
results for antisense therapies now being developed to fight other genetically linked nervous
system diseases like amyotrophic lateral sclerosis and Huntington
disease.
The researchers from the University's Institute of Infection and Global Health ranked the top 100 pathogens affecting humans and the top 100 affecting domestic animals using a
system which, they believe, will help governments across the continent plan for risks associated with the spread of infectious
diseases, including as a
result of climate change, and for biosecurity.
«People often end up in the emergency room not necessarily for contagious
diseases but for complications
resulting from chronic conditions like asthma or diabetes or cardiac problems, which cost a lot to our health care
system,» Ram said.
Autoimmune
diseases result when the immune
system mistakes some of the body's proteins for invaders and attacks organs.
«Our
results suggest that ongoing cytokine activation in the nervous
system can contribute to the persistent symptoms of fatigue, pain, and cognitive dysfunction that patients sometimes experience despite having been treated for Lyme
disease.»
This summer, a slew of new studies reported
results on efforts to shift the balance of cells in the immune
system in hopes of keeping
disease at bay.
The GBD 2013
Disease and Injury Incidence and Prevalence Collaborators analysed 35,620 sources of information on disease and injury from 188 countries between 1990 and 2013 to reveal the substantial toll of disabling disorders and the overall burden on health systems from 301 acute and chronic diseases and injuries, as well as 2337 health consequences (sequelae) that result from one or more of these dis
Disease and Injury Incidence and Prevalence Collaborators analysed 35,620 sources of information on
disease and injury from 188 countries between 1990 and 2013 to reveal the substantial toll of disabling disorders and the overall burden on health systems from 301 acute and chronic diseases and injuries, as well as 2337 health consequences (sequelae) that result from one or more of these dis
disease and injury from 188 countries between 1990 and 2013 to reveal the substantial toll of disabling disorders and the overall burden on health
systems from 301 acute and chronic
diseases and injuries, as well as 2337 health consequences (sequelae) that
result from one or more of these disorders.
Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune
system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced
disease after undergoing autologous stem cell transplants (ASCT).
However, in several chronic human
diseases such as inflammatory bowel
disease (IBD), HIV / AIDS, cancer, cardiovascular
disease, and diabetes, the immune
system attacks these normally beneficial bacteria,
resulting in chronic inflammation and contributing to
disease progression.
When someone is infected with the Ebola virus, part of the reason that the
resulting disease is so severe is because the virus causes parts of the immune
system to malfunction.
On 20 September, Zaki posted his
results on the Program for Monitoring Emerging Diseases (ProMED), an online
disease - reporting
system, confirming that the coronavirus tests were positive.
However, even closed
systems have their challenges: on 27 October Marine Harvest announced that they had decided to conclude the second growth phase after the fish suffered damage to their gills as a
result of poisonous algae and a subsequent outbreak of amoebic gill
disease.
Gender differences in the impact of stress on the cardiovascular
system detected in this study emphasize the importance of including enough women in all studies of heart
disease so that their
results can be analyzed separately.
The
results, published today in Nature Immunology, suggest a common biochemical thread to multiple
diseases and point the way to a new class of therapies that could treat chronic inflammation in these non-infectious
diseases without crippling the immune
system.
The immune
system is responsible for protecting the host from foreign pathogens; however, there are many
diseases — known as autoimmune
diseases — that
result from the immune
system attacking the host.
Up to now research has often viewed autoimmune
disease as the
result of immune
system hyperactivity, yet recently it has become increasingly clear that such ailments may also
result from an immune
system those responses are too weak.
A study published Tuesday in eLife reports the
results of a
system that enabled three participants — Degray and two people with amyotrophic lateral sclerosis (ALS, or Lou Gehrig's
disease, a neurodegenerative
disease that causes progressive paralysis)-- to type at the fastest speeds yet achieved using a BCI — speeds that bring the technology within reach of being practically useful.
Research Summary: CF is a multi-organ
system disease, however the hallmark clinical manifestations
result in respiratory failure and gastrointestinal complications.
Taken together, these
results demonstrate that the Emk protein kinase is essential for maintaining immune
system homeostasis and that loss of Emk may contribute to autoimmune
disease in mammals.
The
resulting data are being combined in a
systems biology approach with high - resolution clinical phenotyping and findings obtained with a large array of established and novel in vitro, ex vivo and in vivo
disease models to identify
disease - associated genetic variants,
disease - defining molecular signatures, and potential targets for therapeutic intervention.
In the paper, the researchers conducted blood tests on a few dozen people and found that the presence of pre-existing adaptive immune responses in humans to either Cas9 homolog «may hinder the safe and efficacious use of the Cas9 / gRNA
system to treat
disease, and may even
result in significant toxicity to patients.»
These
results suggest that the optical biosensor
system could be used to screen for compounds that block EGFR and many other receptors, potentially speeding up the hunt for drugs against several
diseases.
Many of today's most severe
diseases come as a
result of immune
system dysregulation.
The
diseases can be caused by viruses as well as DNA mutations, and the data show that the drugs help the immune
system to recognize and attack cancers
resulting from either cause.
These
results suggest that the serotoninergic
system may be not involved in the pathogenesis of depressive symptoms in AD patients, and it may be involved in other aspects of
disease pathophysiology like cognitive symptoms and psychosis.
Parkinson's
disease (PD) and such neurodegenerative
diseases as Huntington's and Alzheimer's are characterized by protein misfolding,
resulting in toxic accumulations of proteins in the cells of the central nervous
system.
Friedreich's ataxiais an inherited
disease that causes progressive damage to the nervous
system,
resulting in symptoms ranging from gait disturbance to speech problems; it can also lead to heart
disease and diabetes.The ataxia of Friedreich's ataxia
results from the degeneration of nerve tissue in the spinal cord, in particular sensory neurons essential (through connections with the cerebellum) for directing muscle movement of the arms and legs.
Autoimmune
diseases such as rheumatoid arthritis and type 1 diabetes
result when the body's immune
system mistakenly attacks its own tissue.
These cells have the ability to cross the blood - brain barrier and travel directly into the nervous
system to improve blood flow to the brain and repair some of the nerve damage which has occurred as a
result of your degenerative
disease or neurological injury.
Integrated
systems biology approaches can identify gene regulatory networks, such as immune, stress and other regulatory responses, and link them with physiologic states.6 This bioinformatics approach provides an unbiased view of the immune
system profile, and can be linked to changes in environmental conditions.7 These network approaches, while often applied to identifying
disease profiles, can be used to identify salutary states as well, such as that which might
result from intensive meditation.
These data are comparable to
results obtained with more traditional individual tests of each of the relevant behaviors, suggesting that this
system might provide a high - throughput means to quickly screen and characterize different rodent
disease models.
Autoantigens trigger the immune
system to produce antibodies that attack the body's own components,
resulting in autoimmune
disease.