Sentences with phrase «system disorders including»

His main research focus and clinical interest is fluid biomarkers for central nervous system disorders including Alzheimer's disease, for which he has developed new diagnostic tests.

Corey Goodman (pictured left) has long seen the therapeutic potential of neuroscience, a field that encompasses a broad range of potential pharmaceutical targets and nervous system disorders including chronic pain, mental illness, and spinal chord injuries.

Not exact matches

This has been great for agricultural efficiency, but animal welfare activists have criticized the practice for creating birds that have major health issues due to their size, including leg disorders, weakened immune systems, and cardiovascular problems.

«This includes musculoskeletal disorders, gastrointestinal disorders and, importantly, depression (which weakens the immune system and makes people more prone to conditions such as flu).

Plastic eventually breaks down into micro particles, which then make their way into plankton, and thus the entire seafood chain (including any fish you might eat)-- potentially causing immune system disorders, endocrine disruption, and developmental problems in children;

Scientists have linked BPA to a growing list of ailments: cancer, reproductive and cardiovascular system disorders (including damage to the prostate gland, infertility and early puberty), brain and neurological system dysfunctions, behavioral problems, diabetes and obesity.

Lupus is an autoimmune disorder that affects the rheumatic system, which includes the muscles, joints and connective tissues, but it can affect other organs, too, according to the Lupus Foundation of America.

Every exposure to radiation poses health risks, including programmed cell death, genetic mutations, cancers, leukemia, birth defects, and reproductive, immune and endocrine system disorders.

Studying itching sensations is a relatively new field, but if we look at the number of diseases where itch is a major symptom, it includes not only atopic dermatitis but also nervous system disorders such as multiple sclerosis, as well as infection and end stage kidney disease.

This would impact a range of funding areas, including research on kidney and lung disorders, digestive diseases, central nervous system injuries, and sensory loss.

«Our findings contribute to a growing body of evidence that immune system dysfunction, including inflammation, may be involved in the pathophysiology of major psychiatric disorders in some individuals.

A version of Corexit was widely used after the 1989 Exxon Valdez spill and, according to a literature review performed by the group the Alaska Community Action on Toxics, was later linked with health impacts in people including respiratory, nervous system, liver, kidney and blood disorders.

The researchers are now investigating whether the ECO system is effective against other visual disorders, including Stargardt disease, which is a form of inherited juvenile macular degeneration, primarily affecting the central portion of the visual field.

It could also lead to the development of new therapies against other more common neurodegenerative disorders of the central nervous system, as well as diseases related to the propagation of pathological proteins, including Parkinson's and Alzheimer's.

One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune system, new research suggests.

They studied these correlations in 65 complex diseases affecting almost every system in the body, including arthritis, depression and lung cancer, and in 95 Mendelian disease groups (representing 213 disorders).

Researchers, including a team from Children's National Health System, have identified head circumference and head tilting reflex as two reliable biomarkers in the identification of autism spectrum disorders (ASD) in children that are between 9 and 12 months of age.

Long - term sleep loss may affect the cardiovascular, endocrine, immune and nervous systems with severe consequences including hypertension, obesity and mental health disorders, among others.

The new findings may also have implications for the treatment of several disorders involving similar neural systems, including one Alzheimer's disease.

Disturbances and abnormalities within these networks and their connections have been implicated in various mental diseases and disorders, including those related to the somatosensory system.

That includes revisiting the hygiene hypothesis, which holds that a lack of childhood exposure to microbiota and other potentially infectious agents may hinder the development of the immune system and increase susceptibility to immunological disorders.

Gulf War syndrome (GWS) is the name given to a variety of psychological and physical symptoms, including increases in the rate of immune system disorders and birth defects, reported by veterans of the Gulf War.

Others have previously speculated that the biological basis of psychiatric disorders such as PTSD includes a shift in the balance between different signalling systems in the brain but none has yet proved it.

This condition is characterized by central nervous system impairments — including cognitive and memory problems, mood dysfunction, sleep disorders and chronic fatigue — and systemic symptoms such as gastrointestinal problems and hypersensitive skin.

The Division of Pulmonary Medicine deals with the breath of life in all its aspects: control of breathing; sleep disorders; obstruction to airflow in the common diseases of upper and lower airways such as croup, bronchiolitis, asthma, cystic fibrosis, and bronchopulmonary dysplasia; restriction to lung function from disorders affecting the chest wall, the musculature, the nervous system, or lung tissue itself; congenital anomalies; accidents such as inhalation of foreign bodies, hydrocarbons, or toxic gases; secondary effects of non-pulmonary system disorders such as gastrointestinal reflux, myopathy, or cardiac dysfunction; disease of the upper respiratory tract including rhinitis and sinusitis; and so on.

This approach is now being used to derive embryonic stem cells from a variety of strains including disease models from which in vitro tools are in demand, including mouse models of Alzheimer's disease, cytogenetic disorders (Turner's syndrome and Down syndrome), and tool strains for systems genetics.

Columbus, OH (Scicasts)-- One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune system, new research suggests.

USC - ICT has built on sophisticated, yet low - cost gaming technologies to develop interactive systems for clinical applications, including a program called Virtual Iraq / Virtual Afghanistan that shows promise for ameliorating symptoms of post-traumatic stress disorder.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

Phagocyte disorders (innate)- phagocytes include many white blood cells of the innate immune system, and these cells patrol the body eating any pathogens they come across.

Because the BHR also includes longitudinal data from many healthy adults, the collaboration may also increase knowledge about the basic functioning of the olfactory system beyond its role in brain disorders.

Current research includes spin relaxation and decoherence in quantum dots due to spin - orbit and hyperfine interaction; non-Markovian spin dynamics in bosonic and nuclear spin environments; generation and characterization of non-local entanglement with quantum dots, superconductors, Luttinger liquids or Coulomb scattering in interacting 2DEGs; spin currents in magnetic insulators and in semiconductors; spin Hall effect in disordered systems; spin orbit effects in transport and noise; asymmetric quantum shot noise in quantum dots; entanglement transfer from electron spins to photons; QIP with spin qubits in quantum dots and molecular magnets; macroscopic quantum phenomena (spin tunneling and coherence) in molecular and nanoscale magnetism.

Treatment of disorders of the central nervous system including malignant, benign and functional diseases, Stereotactic radiosurgery (SRS) via both Gamma Knife and Linear Accelerator platforms, Stereotactic ablative radiation (SABR), Proton Beam Therapy (PBT), External beam radiation therapy (EBRT), Intensity - modulated radiation therapy (IMRT), Volumetric arc therapy (VMAT), Image - guided radiation therapy (IGRT)

The endocannabinoid system regulates energy homeostasis through G protein — coupled cannabinoid - 1 receptors5, 6 located in the central nervous system and in various peripheral tissues, including adipose tissue, muscle, the gastrointestinal tract, and the liver.7 While peripheral cannabinoid - 1 receptor activation decreases adiponectin production in adipocytes, 8 central cannabinoid - 1 receptor activation in preclinical studies stimulates eating, decreases muscle, and stimulates hepatic and adipose tissue lipogenic pathways in animal models of obesity.9 In genetic and diet - induced obesity, rimonabant, a selective cannabinoid - 1 receptor blocker, reduces overactivation of the central8, 10 and peripheral11, 12 endocannabinoid system8, 10,13 and prevents weight gain and associated metabolic disorders, thus revealing a novel strategy for the treatment of obesity and related cardiometabolic disorders.

They have also been linked to disorders of the central nervous system including anxiety, depression, autism and multiple sclerosis, which may be a consequence of an ecosystem that has fallen out of balance.

Other problems that have been anecdotally associated with children of both sexes who were fed soy - based formula include extreme emotional behavior, asthma, immune system problems, pituitary insufficiency, thyroid disorders and irritable bowel syndrome.

Turmeric has been used traditionally in India for thousands of years as a remedy for an endless list of ailments, including aches, pains, sprains, wounds, and disorders of the liver, lung, digestive system and skin.

Some of the first signs of vitamin D deficiency include tooth decay and bleeding gums but if this issue goes unaddressed for a prolonged period of time it can lead to digestive, immune system, and brain disorders.

Medical problems associated with gluten intolerance are legion, and include autism, multiple sclerosis, ADD, ADHD, allergies, osteoporosis, repetitive strain or stress injury, irritable bowel syndrome, colitis and other digestive system disorders.

When antioxidants in blueberry, strawberry and spinach are combined, they together protect the nervous system by inhibiting an enzyme that may be involved in certain neurologic disorders, including autism, depression and schizophrenia.

Pollutants in water include arsenic, a known carcinogen, and mercury, which is linked to nervous system disorders, according to the U.S. Geological Survey (USGS).

Some of the signs and symptoms include skin disorders, edema of the mouth and throat, swollen, cracked lips, hair loss, reproductive problems, sore throat, itchy and red eyes, and degeneration of the liver and nervous system.

It revs up autophagy, the internal garbage - disposal system in the body that helps cells eliminate damaged molecules, including those linked to Alzheimer's disease and other neurological disorders.

Neurotoxins can cause many nervous system disorders, including peripheral neuropathy, Parkinson's disease, dementia, seizures, and even death.

However, long - term studies on the effects of fluoride are showing that it can cause a multitude of health issues including cancer (specifically bladder), gum disease, thyroid dysfunction, kidney and liver disease, genetic defects, endocrine imbalance, nervous system disorders and bone disease including fluorosis.

They may include thyroid damage, immune system breakdown, reproductive disorders (including infertility), ADD / ADHD and other behavioral and learning disabilities, as well as depression, anxiety and other mental health issues.

[34] The outcome can be serious and include abnormal heartbeat [35], low body temperature [36], and nervous system disorders.

Excess consumption of polyunsaturated oils has been shown to contribute to a large number of disease conditions including increased cancer and heart disease; immune system dysfunction; damage to the liver, reproductive organs and lungs; digestive disorders; depressed learning ability; impaired growth; and weight gain.31

«If not dealt with, accumulated toxins can contribute to a wide range of conditions, including cancer, immune - system disorders, mental problems, fatigue, headaches and skin problems,» says Shari Lieberman, Ph.D., author of Dare to Lose: 4 Simple Steps to a Better Body.

Decades of textbook teaching could be overturned by discovery... Scientists have discovered a previously unknown link between the brain and the immune system that could help explain links between poor physical health and brain disorders including Alzheimer's and depression.