Newer CXCR4 antagonists are under clinical evaluation for therapeutic intervention in various cancers, hematologic and vascular disorders, HIV infection, and other immune
system disorders involving the modulation of the SDF - 1 / CXCR4 axis, such as rheumatoid arthritis and lupus [54 - 56].
Not exact matches
They may have recently broken up with a girlfriend or boyfriend; failed an exam or had a decline in school performance; shown signs of an eating
disorder; or have become
involved somehow with the justice
system.
«Our findings contribute to a growing body of evidence that immune
system dysfunction, including inflammation, may be
involved in the pathophysiology of major psychiatric
disorders in some individuals.
One way to fight diseases including HIV infection and autoimmune
disorders could
involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune
system, new research suggests.
The findings, published in Nature in July, could unearth the secrets of neurological diseases and
disorders, like multiple sclerosis and Alzheimer's, that may
involve the immune
system.
Both
disorders, he says, may
involve abnormally low levels of dopamine, and may be seen on some level as a failure of the avoidance
system.
The Weizmann Institute's Prof. Alon Chen, together with his then PhD student Dr. Orna Issler, investigated the molecular mechanisms of the brain's serotonin
system, which, when misregulated, is
involved in depression and anxiety
disorders.
The studied gene is
involved in the circadian
system, which has previously been shown to be implicated in mental
disorders such as bipolar
disorder, which intriguingly is comorbid with migraine.
Neurofibromatosis is one of at least 60 genetic diseases called neurocutaneous
disorders that
involve the skin, central nervous
system, and / or peripheral nervous
system, according to a comprehensive review article in the journal Current Neurology and Neuroscience Reports by neurologists at Loyola University Medical Center and Loyola University Chicago Stritch School of Medicine.
According to Miller, «This work suggests that enhanced vesicular filling can be sustained over time and may be a viable therapeutic approach for a variety of central nervous
system disorders that
involve the storage and release of dopamine, serotonin, or norepinephrine.»
The new findings may also have implications for the treatment of several
disorders involving similar neural
systems, including one Alzheimer's disease.
In other words, it looks as though the immune
system is somehow
involved in the development of mood
disorders,» says Michael Eriksen Benrós, MD and PhD from Aarhus University and Psychiatric Centre Copenhagen.
He uses the paradigm of nuclear hormone receptor activation / signaling and the contribution of this process to myeloid cell differentiation, function, and to diseases,
involving these cells, such as atherosclerosis, tissue regeneration, metabolic, and various inflammatory
disorders, as his model
systems.
Columbus, OH (Scicasts)-- One way to fight diseases including HIV infection and autoimmune
disorders could
involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune
system, new research suggests.
The study, which is published in PNAS, paves the way for more individualized treatment of diseases
involving the immune
system, e.g. autoimmune
disorders, allergies and various forms of cancer.
Annotations showed genes
involved in gastrointestinal and neurological diseases; endocrine
system disorders; metabolism; perception; bone and limb morphogenesis; growth; and the development of the muscular, cardiovascular, and nervous
systems.
In the fall of 2012, their group demonstrated that misfolded versions of α - synuclein, the protein implicated in Parkinson's disease, can be transmitted from cell to cell in mouse models, adding weight to a hypothesis that a common mechanism of neurodegenerative
disorders could
involve the passage of misfolded proteins through the central nervous
system.
One theory is that panic
disorder involves an overly sensitive «suffocation alarm
system» in the brain that evolved to protect us from suffocating, and that panic attacks result when this alarm gets triggered by signals of impending suffocation like rising carbon dioxide levels.
With an animal model that replicates at least some aspects of OCD, researchers can dig deeper into the specific neurotransmitters and
systems involved in the
disorder.
However, it's taken a very long time not just to accept the concept of addiction as a disease of the brain, but actually to endorse it and recognize that the healthcare
system needs to be
involved both in the prevention and treatment of substance use
disorders.
Production of a compound (β - hydroxybutrate) that blocks part of the immune
system involved in inflammatory
disorders like diabetes, rheumatoid arthritis, or Alzheimer's disease
Turns out while you sleep, a plumbing
system called the glymphatic
system opens up between the brain cells and literally flushes out toxic molecules
involved in neurodegenerative
disorders.
The castor oil pack works well to speed healing of many
disorders specifically those
involving the digestive
system.
When antioxidants in blueberry, strawberry and spinach are combined, they together protect the nervous
system by inhibiting an enzyme that may be
involved in certain neurologic
disorders, including autism, depression and schizophrenia.
The histaminergic
system is
involved in basic physiological functions, such as the sleep - wake cycle, energy and endocrine homeostasis, sensory and motor functions, cognition, and attention, which are all severely affected in neuropsychiatric
disorders.
Because of this, it is being investigated as a treatment for brain and nervous
system disorders that
involve oxidative stress.
It also
involves a hormonal
disorder of pituitary - thyroid or pituitary - ovary, according to this iconic pioneer of the Lymphatic
System.
The changes in the brain seen in people who have seizure
disorders are very similar in nature to that of chronic pain and thought to
involve increased excitability of neurons, both in the central and peripheral nervous
system.
Good and smart people
involved in education reform can easily be stricken with this
disorder in which they visualize a desirable reform policy and then imagine that they can simply impose that policy on our education
system and that it will come out as they want.
Pets with seizure
disorders, tumors of the spine and brain, intervertebral disc disease, inflammatory brain diseases, Wobbler's syndrome, neuromuscular diseases, and other conditions
involving the nervous
system can be diagnosed and treated by a veterinary neurologist.
ACT - activated clotting time (bleeding
disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal
disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal
disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver
disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver
disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid
disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver
disorders) Glob globulin (liver, immune
system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney
disorders, adrenal gland
disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney
disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells
involved in clotting (bleeding
disorders) PT prothrombin time (bleeding
disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver
disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver
disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver
disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney
disorders) VWF VonWillebrands factor (bleeding
disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)
Canonsburg, Pennsylvania About Blog The Doctors of Skraitz Chiropractic evaluate and provide treatment for a wide variety of conditions
involving the nervous
system i.e. whiplash injuries, low back pain / disc herniations / sciatica, migraines, worker's compensation injuries, sports injuries, learning disabilities and childhood
disorders, nutritional counseling, mild traumatic brain injuries / concussions, and maternal & pediatric health.
This section contains State and local examples of effective practices to serve families affected by substance use
disorders and who are
involved in the child welfare
system.
Pediatric rheumatic diseases (PRDs) are chronic multisystem
disorders,
involving acute and chronic tissue inflammation of the musculoskeletal
system, blood vessels, and skin (Cassidy & Petty, 1995).
Published in the journal BMJ Open, the WA research also found that one in three of young people in detention had foetal alcohol spectrum
disorder (FASD)-- the highest known rate of FASD among any population
involved in the justice
system worldwide.
It is also
involved with brain development and a
disorder in this
system could lead to an increase in aggressiveness and impulsivity (Morley & Hall, 2003).
If a mental health professional is NOT competent in personality
disorders and family
systems constructs, then that professional should not be diagnosing or treating family dynamics
involving the presence of personality
disorder dynamics, and should instead refer the client to a professionally competent child custody evaluator or therapist.
Tom's specialty areas include evaluations, treating co-occurring
disorders, individuals
involved with the criminal justice
system, personality
disorders, dialectical behavior therapy and working with individuals that have struggled with previous treatment episodes or providers.
An attachment - based model of «parental alienation» defines the dynamics
involved in «parental alienation» across multiple levels of integrated analysis, 1) the family
systems level, 3) the personality
disorder level, and 3) the level of the attachment
system.
They
involve special training in the assessment and treatment of cognitive, affective, or behavioral mental and emotional
disorders within the context of marriage and family
systems through the application of therapeutic and family
systems theories and techniques and delivery of services to individuals, couples, and families, singularly or in groups, for the purpose of treating such
disorders.
National Center on Substance Abuse and Child Welfare (NCSACW) Source: Substance Abuse and Mental Health Administration The mission of the NCSACW is to improve
systems and practice for families with substance use
disorders who are
involved in the child welfare and family judicial
systems by assisting local, State and tribal agencies.