Ian Wilmut of the Roslin Institute in Edinburgh, whose team created Dolly the sheep, described two animals, one sheep and one cow that appeared healthy at birth but later died from lung and immune
system disorders respectively.
Their negative affectivity, poor emotion regulation, and imbalances in the different emotional
systems in the brain (e.g., the fear, the care, the seeking
systems) predict both internalizing and externalizing
disorders (e.g., depression and aggression,
respectively).