Sentences with phrase «system disorders such»

Traumatic injuries, IVDD, spinal cord inflammation and nervous system disorders such as degenerative myelopathy can cause weakness and partial or complete paralysis.

These two amino acids may contribute to neurodegenerative conditions such as multiple sclerosis, Alzheimer's, Huntington's disease, and other nervous system disorders such as epilepsy, ADD / ADHD and migraines.

The baby is already predisposed to heart problems (irregular heart beats, fast heart beat and overly excitable heart leading to rhythm abnormalities), and nervous system disorders such as anxiety at birth as a result of exposure to caffeine in - utero.

The Division of Pulmonary Medicine deals with the breath of life in all its aspects: control of breathing; sleep disorders; obstruction to airflow in the common diseases of upper and lower airways such as croup, bronchiolitis, asthma, cystic fibrosis, and bronchopulmonary dysplasia; restriction to lung function from disorders affecting the chest wall, the musculature, the nervous system, or lung tissue itself; congenital anomalies; accidents such as inhalation of foreign bodies, hydrocarbons, or toxic gases; secondary effects of non-pulmonary system disorders such as gastrointestinal reflux, myopathy, or cardiac dysfunction; disease of the upper respiratory tract including rhinitis and sinusitis; and so on.

Maybe we can eventually use this relationship between musical experience and the motor system to help people with motor - system disorders such as Parkinson's disease.

Skin rash and nervous system disorders such as dizziness or headache occurred less frequently under the elvitegravir fixed combination in patients without prior treatment.

Studying itching sensations is a relatively new field, but if we look at the number of diseases where itch is a major symptom, it includes not only atopic dermatitis but also nervous system disorders such as multiple sclerosis, as well as infection and end stage kidney disease.

Not exact matches

Analysts point to three main therapeutic areas — cancer, central nervous system disorders (such as Alzheimer's, depression and pain), and cardiovascular disease — as core strengths of Canada's biopharmaceutical research industry.

«This includes musculoskeletal disorders, gastrointestinal disorders and, importantly, depression (which weakens the immune system and makes people more prone to conditions such as flu).

Its drug development expertise is being applied primarily to the fields of pain management, central nervous system disorders, acute organ injury and metabolic diseases such as nonalcoholic fatty liver disease / nonalcoholic steatohepatitis.

High levels of stress and anxiety have significant physical effects on our bodies, such as stomach pain, muscle tension, chronic pain, headaches, weakened immune systems and the development of other mental health disorders.

To risk a generalization even more reckless than those I have already made: from the time of the pre-Socratics, all the great speculative and moral systems of the pagan world were, in varying degrees, confined to this totality, to either its innermost mechanisms or outermost boundaries; rarely did any of them catch even a glimpse of what might lie beyond such a world; and none could conceive of reality except as a kind of strife between order and disorder, within which a sacrificial economy held all forces in tension.

In rare cases, failure to gain weight can turn out to be a result of a lung problem, such as cystic fibrosis; a nervous system problem, such as cerebral palsy; a chromosome problem, such as Down syndrome; heart disease; anemia; or a metabolic or an endocrine disorder, such as growth hormone deficiency.

Baby's digestive system at this stage is quite delicate, and hence they are at high risk of gastrointestinal disorders due to such kind of foods.

The full results haven't yet been published, but what has been revealed so far of this «antisense» therapy suggests we have overcome the biggest obstacle — how to deliver such therapies — at least in disorders that affect the nervous system.

If left to accumulate, this «junk» can overwhelm nerve cells» quality control systems, triggering incurable brain disorders such as Alzheimer's, Parkinson's and Huntington's.

The immune system's reach within the CNS is extensive, probably contributing to the initiation and pathogenesis of neurodegenerative diseases, neurodevelopmental disorders such as autism, and mental health disorders such as schizophrenia.

«In addition, our computer - vision system can be applied to detect states in which the human face may provide important clues as to health, physiology, emotion, or thought, such as drivers» expressions of sleepiness, students» expressions of attention and comprehension of lectures, or responses to treatment of affective disorders.»

«The practice of the Wim Hof Method may lead to tonic changes in autonomous brain mechanisms, a speculation that has implications for managing medical conditions ranging from diseases of the immune system to more intriguingly psychiatric conditions such as mood and anxiety disorders,» said Diwadkar, professor of psychiatry and behavioral neurosciences.

These drugs are also frequently used to manage central nervous system (CNS) disorders associated with a pathologically permeable BBB, such as with brain tumors and multiple sclerosis.

Parkinson's disease is a degenerative disorder of the central nervous system that causes a person to lose control of motor movements, such as the ability to move his or her hands, arms, and legs.

Although prior twin studies had hinted that nonheritable factors contribute to some autoimmune disorders, such as multiple sclerosis, the recent analysis was one of the first to quantify genetic and environmental effects on the general immune system.

The studied gene is involved in the circadian system, which has previously been shown to be implicated in mental disorders such as bipolar disorder, which intriguingly is comorbid with migraine.

Such a grid would provide a coordinate system to standardise studies linking abnormalities in brain anatomy to neurological and psychiatric disorders.

The vectors are customizable and could potentially be used as part of a gene therapy to treat neurodegenerative disorders that affect the entire central nervous system, such as Huntington's disease, or to help map or modulate neuronal circuits and understand how they change during disease.

«Such evidence quantifying shared genetic risk factors among traditional psychiatric diagnoses will help us move toward classification that will be more faithful to nature,» said Bruce Cuthbert, Ph.D., director of the NIMH Division of Adult Translational Research and Treatment Development and coordinator of the Institute's Research Domain Criteria (RDoC) project, which is developing a mental disorders classification system for research based more on underlying causes.

«Because JAK3 has such an isolated role in the immune system, we believe that inhibiting it will lead to a suppression of immune responses which could be used to treat autoimmune disorders like psoriasis and rheumatoid arthritis.

«A growing body of evidence suggests that immune system activation, such as that caused by bacterial and viral infections, can play important roles in many brain disorders,» explained William Carlezon, PhD, chief of the Division of Basic Neuroscience at McLean Hospital, and senior author of the paper.

Disrupted fetal immune system development, such as that caused by viral infection in the mother, may be a key factor in the later appearance of certain neurodevelopmental disorders.

With an estimated 60,000 drug overdose deaths in 2016 alone, the researchers emphasize the need for the American health care system to embrace medications such as methadone to treat opioid use disorder, provide addiction treatment in primary care clinics and develop non-addictive alternatives for chronic pain.

The procedural memory system has previously been implicated in other developmental disorders, such as dyslexia and developmental language disorder, say the study's senior researcher, Michael T. Ullman, PhD, professor of neuroscience at Georgetown.

So far, DARPA has released two calls for grant applications, with at least one more likely: The first, called SUBNETS (Systems - Based Neurotechnology for Emerging Therapies), asks researchers to develop novel, wireless devices, such as deep brain stimulators, that can cure neurological disorders such as posttraumatic stress (PTS), major depression, and chronic pain.

Research has shown that the immune system is linked to certain psychiatric disorders, such as schizophrenia and bipolar disorder.

Because these batteryless sensors could also be used to stimulate nerves and muscles, the technology also opens the door to «electroceuticals» to treat disorders such as epilepsy or to stimulate the immune system or tamp down inflammation.

Such changes in bacteria triggered chronic colitis in mice genetically prone to this disorder, due to abnormal immune systems.

Others have previously speculated that the biological basis of psychiatric disorders such as PTSD includes a shift in the balance between different signalling systems in the brain but none has yet proved it.

This condition is characterized by central nervous system impairments — including cognitive and memory problems, mood dysfunction, sleep disorders and chronic fatigue — and systemic symptoms such as gastrointestinal problems and hypersensitive skin.

Mouse vocalizations are also used as a model system in research into neuropsychiatric disorders such as autism.

Many disorders, such blindness to paralysis, come down to a break in the flow of signals through our nervous system.

Such a system will enable ethical and more rapid and accurate testing of experimental drugs before the clinical trial stage and advance studies of genetic and environmental causes of central nervous system disorders.

He uses the paradigm of nuclear hormone receptor activation / signaling and the contribution of this process to myeloid cell differentiation, function, and to diseases, involving these cells, such as atherosclerosis, tissue regeneration, metabolic, and various inflammatory disorders, as his model systems.

Her aim is to understand, at the molecular level, the mechanisms that control communication between the brain, immune system, and blood vessels — with the ultimate goal of designing new therapies that slow, stop, or reverse the progression of a wide range of neurological disorders, such as MS. Recently, Dr. Akassoglou's lab identified how microglia — a type of immune cell that acts as the brain's first line of defense — are activated when fibrinogen enters the brain or spinal cord.

Newer CXCR4 antagonists are under clinical evaluation for therapeutic intervention in various cancers, hematologic and vascular disorders, HIV infection, and other immune system disorders involving the modulation of the SDF - 1 / CXCR4 axis, such as rheumatoid arthritis and lupus [54 - 56].

Overall, the research is intended to lead to a clearer understanding of the power and limitations of such modeling systems, while uncovering potential areas of convergence in different genetic forms of autism spectrum disorders.

McCormick said the spike timing is important for fine perception and may underlie problems in the nervous system and in psychiatric disorders, such as schizophrenia, where the timing problem might cause confusion.

Children with non-chromosomal birth defects, such as congenital heart malformations or nervous system disorders, are more than twice as likely to end up with childhood cancer as kids without a birth defect, according to a study presented today (April 15) at the annual meeting of the American Association for Cancer Research (AACR) in Chicago.

Applications in clinical neuroscience have been particularly useful, and have provided insights into systems - level cortical and subcortical anomalies of functional connectivity in neurodevelopmental disorders such as attention - deficit / hyperactivity disorder (ADHD, Castellanos and Proal, 2012) and schizophrenia (Yu et al., 2012).

Ms. Wojtal: I am looking at how we can apply the CRISPR / Cas9 system to treat monogenic disorders - specifically editing pathogenic mutations such as duplications, as well as modulating disease modifier genes.

However, they say the work at least proves the potential for mRNA therapy to successfully treat not only hemophilia B but also other human disorders, such as hemophilia A (caused by faulty clotting factor VIII) or a variety of diseases of the liver, central nervous system, lung and eyes.

Less commonly, a persistent infection may signal a more serious condition, such as diabetes or an immune system disorder.