The origin of the mouse as the principal model
system for biomedical research dates back to the start of human civilization.
Not exact matches
Then, this past April, she teamed up with three other scientific superstars — Bruce Alberts, former president of the National Academy of Sciences and former editor - in - chief of Science; Marc W. Kirschner, founding chair of the Department of
Systems Biology at Harvard Medical School; and Harold Varmus, Nobel laureate, former director of NIH, and current director of the National Cancer Institute — to publish «Rescuing US
biomedical research from its systemic flaws,» a critique and call
for reform that seems already to have altered the course of the workforce debate, in the Proceedings of the National Academy of Sciences (PNAS).
«The misalignment of resources in
biomedical research could be likened to poor budgeting of household finances,» said senior study author Andrey Rzhetsky, PhD, professor of genetic medicine and senior fellow at the Institute
for Genomics and
Systems Biology at the University of Chicago.
The MDC researchers are fascinated by the new opportunities the CRISPR - Cas9
system offers
for biomedical research, but strictly reject genetic modification of the human germline.
Yet even as teams developed the CRISPR / Cas9 gene - editing
system for biomedical and basic
research purposes, multiple groups have been on the lookout
for better versions of the molecular scalpel.
«With Teresa Woodruff's
research using Draper's human organ
system platform, we have a compelling demonstration of the importance of a microenvironment that permits cells to function in vitro as they would in vivo, and the power of being able to interconnect organ models on a platform and operate them in a stable and precise manner
for weeks to months,» said Jeffrey T. Borenstein, a
biomedical engineer at Draper.
Five researchers who study a cellular
system for fixing misfolded proteins, deep brain stimulation
for Parkinson's disease, and breast cancer genetics have won this year's prestigious Lasker Awards
for biomedical research.
The
research has important implications
for the fundamental understanding of translation in living
systems, as well as intriguing potential in the
biomedical arena.
The invention, called a «nonlinear mirror» by the researchers, could help advance nonlinear laser
systems that are used
for chemical sensing, explosives detection,
biomedical research and potentially many other applications.
The Institute
for Systems Biology is a nonprofit
biomedical research organization based in Seattle.
With her recent groundbreaking findings in the field of RNA - mediated regulation based on the CRISPR - Cas9
system, E. Charpentier has laid the foundation
for the development of a novel, highly versatile and specific genome editing technology that is revolutionizing life sciences
research and could open up whole new opportunities in
biomedical gene therapies.
ABOUT LA JOLLA INSTITUTE Founded in 1988, the La Jolla Institute
for Allergy and Immunology is a
biomedical research nonprofit focused on improving human health through increased understanding of the immune
system.
The Institute
for Systems Biology is a nonprofit
biomedical research organization based in Seattle, Washington.
The ASHG Advocacy Award, new in 2015, honors individuals or groups who have exhibited excellence and achievement in applications of human genetics
for the common good, in areas such as facilitating public awareness of genetics issues, promoting funding
for biomedical research, and integrating genetics into health
systems.
In addition to caring
for the health needs of all animals they provide expertise to our global food
system, conduct
biomedical and agricultural
research, offer ecosystem management, and serve as public health officers.