Sentences with phrase «system genes from»

When the t - shirt wearer and sniffer had very different immune system genes from each other the t - shirts were rated as smelling very attractive or very sexy even.

As Wroblewski, Parham, and co-authors explain in a PLOS Biology study published online today, they analyzed stool samples dating back 15 years and sequenced immune system genes from 125 chimpanzees.

Not exact matches

They are seeking damages from former CEO Gene Isenberg and current CEO Anthony Petrello as well as members of the board of directors in a federal class action lawsuit filed by the Erie County Employees Retirement System.

This is the group of genes which act as the immune system markers on cells, protecting them from being attacked by the system's anti-bodies.

Genes related to the serotonin transporter, cardiac channelopathies, and the development of the autonomic nervous system are the subject of current investigation.44 The serotonin transporter recovers serotonin from the extracellular space and largely serves to regulate overall serotonin neuronal activity.

It has been estimated that 5 % to 10 % of infants who die from SIDS have novel mutations in the cardiac sodium or potassium channel genes that result in long QT syndrome as well as in other genes that regulate channel function.44 A recent report described important new molecular and functional evidence that implicates specific SCN5A (sodium channel gene) β subunits in SIDS pathogenesis.47 The identification of polymorphisms in genes pertinent to the embryologic origin of the autonomic nervous system in SIDS cases also lends support to the hypothesis that a genetic predisposition contributes to the etiology of SIDS.

A second area challenges teams who receive funding from Safe Genes to design systems for controlling and reversing gene editing tools like CRISPR — Cas9.

«Gene - delivery system prevents vision loss from inherited eye disease: Initial testing in animal models holds promise for treating Leber congenital amauroisis and other congenital visual disorders.»

«Steep funding cuts for the federal health agencies are counterproductive at a time when innovative research is moving us closer to identifying solutions for rare diseases, new prevention strategies to protect Americans from deadly and costly conditions, advances in gene therapy, new technologies for understanding the brain, and treatments that harness the ability of our immune system to fight cancer.»

The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to test the idea of stimulating the immune system's killer T cells to hunt for the virus more aggressively, in this case using a weakened form of the cold virus to carry three genes from HIV.

These two genes are crucial for tightening the reins on the immune system to prevent it from reacting to benign agents and triggering asthma symptoms.

One gene, she said, would shield its organs from attack by the human immune system; another would revamp its coagulation system to reduce the risk of clots.

«Same switches program taste, smell in fruit flies: Findings help explain how complex nervous systems arise from few genes.»

Researchers from Massachusetts General Hospital (MGH) led a large, international research team that has identified gene mutations associated with a rare congenital condition involving the absence of a nose and often accompanied by defects involving the eye and reproductive systems.

Other genes act like circuit breakers to keep the system from overloading.

Gene drive systems that use genetic approaches to kill mosquitoes, prevent them from breeding, or stop them from transmitting the malaria - causing parasite are under development, but a concern is that mosquitoes could evolve resistance to these techniques, too.

By studying infected cells grown in a laboratory, the team found that a large number of CMV's genes help it hide from the immune system by allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating immune cells to destroy the virus.

The international team used a common computer system so that researchers from around the world could analyze the gene sequences based on their areas of expertise.

Dr Ceri Fielding from Cardiff University's School of Medicine said: «The scale of the effect of CMV's genes on the immune system surprised us.

In a related paper published online today in Nature Biotechnology, Konrad Hochedlinger of the Harvard Stem Cell Institute in Cambridge and his colleagues compared the gene expression patterns in mouse iPS cells derived from white blood cells, muscle precursor cells, immune system cells called B cells, and fibroblasts taken from tail tips.

The system relies on admixture — a genetic principle that argues that when a family migrates across a geographic barrier into a new location, they start mating with the locals; new traits start blending into their gene pool, and this genetic diversity provides a ruler for gauging the distance from home.

Aedes has already been shown to possess extra genes for receptors that detect odors, for proteins that help it purge pesticides from its system, and for controlling the makeup of its outer shell.

When they sequenced the complete genomes of the Y. pestis DNA in those seven individuals, the team found that the bacterial genomes from the earliest samples lacked two genes that helped Y. pestis evade the immune systems of humans and fleas during the Black Death.

The phages» DNA contained some of the genes from another bacteria's immune system.

«This is the first gene drive system in a major worldwide crop pest,» said Akbari, who recently moved his lab to UC San Diego from UC Riverside, where the research began.

When a gene from a dangerous virus, such as rabies or measles, is spliced into the adenovirus genome, the immune system battles both the adenovirus and the inserted gene.

Women prefer the smell of T - shirts worn by men whose major histocompatability complex genes — which encode the proteins that make up an important part of our immune system — are different from their own, and vice versa.

If parasitic infestation occurs sufficiently early in development, it can produce minor deviations from symmetry — hence the adaptive advantage of using asymmetry as a marker to avoid potential mates with poor health, weak genes or a challenged immune system.

The researchers developed algorithms to use in a «systems biology modeling cycle,» in which they repeatedly fit a model to gene expression data obtained from laboratory experiments until a good fit was obtained between the predicted and the measured outcomes.

This webinar will provide an overview of amplicon resequencing — based approaches, from the perspective of investigating the complexity and diversity seen in immune system genes.

In addition, the analysis provided some hints about how chemotaxis evolved from a simple signaling network that responds slowly to environmental cues — primarily by turning on genes — to a multiprotein system that can quickly alter a cell's course.

Research from other scientists at Johns Hopkins, he says, had suggested that some tumors, particularly those that affect the nervous system, have mutations in the ATRX gene, which produces proteins that appear to maintain the length of telomeres, repetitive segments of DNA on the ends of chromosomes that typically shorten each time a cell divides.

Some proteins recycled from jumping gene parts have also proved extremely useful, especially for the immune system.

Factors such as eczema and rhinitis are associated with food allergy, possibly due to a certain gene defect that prevents the skin barrier from forming correctly, leading to possible exposure of the immune system to allergens.

It is surprising to find that a single gene (ESRP), through its ancestral biological role (cell adherence and motility) has been used throughout the animal scale for very different purposes: from the immune system of an echinoderm to the lips, lungs or inner ears of humans,» states professor Jordi Garcia - Fernàndez, of the University of Barcelona's Department of Genetics, Microbiology and Statistics and the IBUB.

Resistance to treatment can originate from many sources — the immune system, the complex landscape of a tumor, or a patient's own genes.

Because it is such a versatile player in the immune system, the gene appears to have been preserved in all animal lineages, from horseshoe crabs to humans.

Alexander Pletnev and colleagues at the National Institute of Allergy and Infectious Diseases in Bethesda, Maryland, and the nearby Walter Reed Army Institute of Research have taken two genes from West Nile virus that encode proteins that form the outer envelope of the virus, and spliced them into the dengue virus type 4, which does not attack the central nervous system.

Gene drives are systems of biased inheritance that enhance a genetic element's ability to pass from parent organism to offspring.

Many bacteria take DNA from other live microbes using a complex system of around 40 genes.

Perhaps that would mean a drug for people who carry the ApoE4 gene, one that would mimic the effects of a parasite without incurring the damage of an infection — a kind of muzzle for the brain's immune system that would keep cells like the astrocytes from attacking healthy neurons.

Research from NC State shows how common immune systems in microbes can be co-opted to turn different genes off at will.

«Our research team is the first to describe a high - throughput in vivo validation system to screen candidate disease genes identified from patients.

Researchers from North Carolina State University have developed a technique that co-opts an immune system already present in bacteria and archaea to turn off specific genes or sets of genes — creating a powerful tool for future research on genetics and related fields.

The reasons for this failing range from insufficient information from which to predict system behavior to the inability of a complex biologic system to be reductively explicable by the basal elements (genes, proteins) from which it emerges (Kim, 2006)(vide infra).

The researchers compared mice with a normal glymphatic system to those with a disabled gene that prevented glial cells from assisting in the fluid flow.

For example, when the researchers decoded the complete sequence of one extrachromosomal circular phage from a disease - causing Staphylococcus, they identified a number of genes that may help this strain evade a host's immune system and that could readily spread to other Staphylococcus bacteria.

Many life - saving products, such as recombinant therapeutic proteins, vaccines, and gene therapy vectors, are produced from large - scale cell culture systems.

While advancing this target discovery work, deCODE will also bring to the alliance its Clinical Genome Miner ™ system in order to validate and prioritize targets emerging from Merck's substantial research programs in mice and gene - expression.

Drawing upon the cell culture expertise of Noriyoshi Sakai, Ph.D., and Kayoko Kurita, of Fukui Prefectural University, the Japanese - U.S. team developed a system that enables immature sperm cells, or spermatagonia, taken from male zebrafish to survive long enough in vitro that they can receive foreign genes inserted by a retrovirus.