Deppmann and his graduate student, Kanchana Gamage, the study's lead author, believe that
axons communicate the death message to each other during
injury as a leftover activity, «borrowed» from the nervous
system's developmental period when
axons are overproduced and then improper or unnecessary connections are eliminated by a similar communication between
axons.
The Yale team found more than 580 different genes that may play a role in regeneration of
axons in nerve cells, something that rarely occurs in adult mammals but is of vital interest to scientists hoping to repair
injuries to the central nervous
system.